Publications by authors named "Louise D Johnson"

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Discovery of an Chemical Probe for BCL6 Inhibition by Optimization of Tricyclic Quinolinones.
Alice C Harnden, Owen A Davis, Gary M Box, Angela Hayes, Louise D Johnson

J Med Chem· April 2023

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Improved Binding Affinity and Pharmacokinetics Enable Sustained Degradation of BCL6 .
Rosemary Huckvale, Alice C Harnden, Kwai-Ming J Cheung, Olivier A Pierrat, Rachel Talbot, Louise D Johnson

J Med Chem· June 2022

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Into Deep Water: Optimizing BCL6 Inhibitors by Growing into a Solvated Pocket.
Matthew G Lloyd, Rosemary Huckvale, Kwai-Ming J Cheung, Matthew J Rodrigues, Gavin W Collie, Louise D Johnson

J Med Chem· December 2021

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Achieving Target Depletion through the Discovery and Optimization of Benzimidazolone BCL6 Degraders.
Benjamin R Bellenie, Kwai-Ming J Cheung, Ana Varela, Olivier A Pierrat, Gavin W Collie, Louise D Johnson

J Med Chem· April 2020

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Dual blockade of the PI3K/AKT/mTOR (AZD8055) and RAS/MEK/ERK (AZD6244) pathways synergistically inhibits rhabdomyosarcoma cell growth in vitro and in vivo.
Jane Renshaw, Kathryn R Taylor, Ryan Bishop, Melanie Valenti, Alexis De Haven Brandon, Louise D Johnson

Clin Cancer Res· November 2013

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