Publications by authors named "Luca Barbero"

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Evolving bioanalytical strategies in the wake of pioneering biotherapeutics.
Federico Riccardi Sirtori, Andrea Di Ianni, Claudio Crosasso, Elisa Bertotti, Francesco Molinaro, Luca Barbero

Bioanalysis· August 2025

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Unlocking the Complexity of Antibody-Drug Conjugates: A Cutting-Edge LC-HRMS Approach to Refine Drug-to-Antibody Ratio Measurements with Highly Reactive Payloads.
Andrea Di Ianni, Kyra J Cowan, Federico Riccardi Sirtori, Luca Barbero

Int J Mol Sci· March 2025

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2023 White Paper on Recent Issues in Bioanalysis: Deuterated Drugs; LNP; Tumor/FFPE Biopsy; Targeted Proteomics; Small Molecule Covalent Inhibitors; Chiral Bioanalysis; Remote Regulatory Assessments; Sample Reconciliation/Chain of Custody - Recommendations on Mass Spectrometry, Chromatography, Sample Preparation Latest Developments, Challenges, and Solutions and BMV/Regulated Bioanalysis - Regulatory Agencies' Inputs on Regulated Bioanalysis/BMV, Biomarkers/IVD/CDx/BAV, Immunogenicity, Gene & Cell Therapy and Vaccine).
Mike Baratta, Wenying Jian, Shawna Hengel, Surinder Kaur, Jennifer Cunliffe, Luca Barbero

Bioanalysis· June 2024

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Leveraging Cross-Linking Mass Spectrometry for Modeling Antibody-Antigen Complexes.
Andrea Di Ianni, Alessio Di Ianni, Kyra Cowan, Luca M Barbero, Federico Riccardi Sirtori

J Proteome Res· March 2024

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Assessing MAPPs assay as a tool to predict the immunogenicity potential of protein therapeutics.
Andrea Di Ianni, Tiziana Fraone, Piercesare Balestra, Kyra Cowan, Federico Riccardi Sirtori, Luca Barbero

Life Sci Alliance· January 2024

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Decorated DNA-Based Scaffolds as Lateral Flow Biosensors.
Simone Brannetti, Serena Gentile, Alejandro Chamorro-Garcia, Luca Barbero, Erica Del Grosso

Angew Chem Int Ed Engl· November 2023

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Bispecific Antibody Detection Using Antigen-Conjugated Synthetic Nucleic Acid Strands.
Davide Mariottini, Sara Bracaglia, Luca Barbero, Sebastian W Fuchs, Christoph Saal

ACS Sens· November 2023

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Preclinical risk assessment strategy to mitigate the T-cell dependent immunogenicity of protein biotherapeutics: State of the art, challenges and future perspectives.
Andrea Di Ianni, Luca Barbero, Tiziana Fraone, Kyra Cowan, Federico Riccardi Sirtori

J Pharm Biomed Anal· September 2023

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Hybrid liquid chromatography high resolution and accuracy mass spectrometry approach for quantification of antibody-drug conjugates at the intact protein level in biological samples.
Luca M Barbero, Andrea Di Ianni, Francesco Molinaro, Kyra J Cowan, Federico Riccardi Sirtori

Eur J Pharm Sci· September 2023

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FEM Simulation of AlSi10Mg Artifact for Additive Manufacturing Process Calibration with Industrial-Computed Tomography Validation.
Cesare Patuelli, Enrico Cestino, Giacomo Frulla, Federico Valente, Guido Servetti, Luca Barbero

Materials (Basel)· June 2023

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Development of a Liquid Chromatography and High-Resolution and -Accuracy Mass Spectrometry Method to Evaluate New Biotherapeutic Entity Processing in Human Liver Lysosomes.
Gabriele Sergio Colangelo, Andrea Di Ianni, Kyra Cowan, Federico Riccardi Sirtori, Luca Maria Barbero

Immunohorizons· June 2022

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Time- and NADPH-dependent inhibition of cytochrome P450 3A4 by the cyclopentapeptide cilengitide: significance of the guanidine group and accompanying spectral changes.
Mirza Bojić, Luca Barbero, Hugues Dolgos, Achim Freisleben, Dieter Gallemann

Drug Metab Dispos· September 2014

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NMR structure of two novel polyethylene glycol conjugates of the human growth hormone-releasing factor, hGRF(1-29)-NH2.
Giuseppe Digilio, Luca Barbero, Chiara Bracco, Davide Corpillo, Pierandrea Esposito

J Am Chem Soc· March 2003

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NMR conformational analysis of antide, a potent antagonist of the gonadotropin releasing hormone.
Giuseppe Digilio, Chiara Bracco, Luca Barbero, Daniela Chicco, Maria D Del Curto

J Am Chem Soc· April 2002

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