Publications by authors named "Luca Biasco"

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In vivo gene editing of human hematopoietic stem and progenitor cells using envelope-engineered virus-like particles.
Vladimir V Botchkarev, Sean Harrington, Matteo Stoppato, Alexander Justen, Casey Kimber, Luca Biasco

Nat Biotechnol· December 2025

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Preclinical lentiviral hematopoietic stem cell gene therapy corrects Pompe disease-related muscle and neurological manifestations.
John K Yoon, Jeffrey W Schindler, Mariana Loperfido, Cristina Baricordi, Mark P DeAndrade, Luca Biasco

Mol Ther· November 2024

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Improving the Assessment of Risk Factors Relevant to Potential Carcinogenicity of Gene Therapies: A Consensus Article.
Jan C Klapwijk, Alberto Del Rio Espinola, Silvana Libertini, Philippe Collin, Mick D Fellows, Luca Biasco

Hum Gene Ther· August 2024

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Tumor immunogenicity dictates reliance on TCF1 in CD8 T cells for response to immunotherapy.
Giulia Escobar, Katherine Tooley, Joan Pagès Oliveras, Linglin Huang, Hanning Cheng, Luca Biasco

Cancer Cell· September 2023

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IS-Seq: a bioinformatics pipeline for integration sites analysis with comprehensive abundance quantification methods.
Aimin Yan, Cristina Baricordi, Quoc Nguyen, Luigi Barbarossa, Mariana Loperfido, Luca Biasco

BMC Bioinformatics· July 2023

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High-throughput analysis of hematopoietic stem cell engraftment after intravenous and intracerebroventricular dosing.
Robert N Plasschaert, Mark P DeAndrade, Fritz Hull, Quoc Nguyen, Tara Peterson, Luca Biasco

Mol Ther· October 2022

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Clonal expansion of T memory stem cells determines early anti-leukemic responses and long-term CAR T cell persistence in patients.
Luca Biasco, Natalia Izotova, Christine Rivat, Sara Ghorashian, Rachel Richardson

Nat Cancer· June 2021

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Long-term lymphoid progenitors independently sustain naïve T and NK cell production in humans.
Natalia Izotova, Christine Rivat, Cristina Baricordi, Elena Blanco, Danilo Pellin, Luca Biasco

Nat Commun· March 2021

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Lentiviral gene therapy for X-linked chronic granulomatous disease.
Donald B Kohn, Claire Booth, Elizabeth M Kang, Sung-Yun Pai, Kit L Shaw, Luca Biasco

Nat Med· February 2020

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A comprehensive single cell transcriptional landscape of human hematopoietic progenitors.
Danilo Pellin, Mariana Loperfido, Cristina Baricordi, Samuel L Wolock, Annita Montepeloso, Luca Biasco

Nat Commun· June 2019

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Highly efficient therapeutic gene editing of human hematopoietic stem cells.
Yuxuan Wu, Jing Zeng, Benjamin P Roscoe, Pengpeng Liu, Qiuming Yao, Luca Biasco

Nat Med· May 2019

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Lentiviral haemopoietic stem/progenitor cell gene therapy for treatment of Wiskott-Aldrich syndrome: interim results of a non-randomised, open-label, phase 1/2 clinical study.
Francesca Ferrua, Maria Pia Cicalese, Stefania Galimberti, Stefania Giannelli, Francesca Dionisio, Luca Biasco

Lancet Haematol· May 2019

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CRISPR-SURF: discovering regulatory elements by deconvolution of CRISPR tiling screen data.
Jonathan Y Hsu, Charles P Fulco, Mitchel A Cole, Matthew C Canver, Danilo Pellin, Luca Biasco

Nat Methods· December 2018

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Dynamics of genetically engineered hematopoietic stem and progenitor cells after autologous transplantation in humans.
Serena Scala, Luca Basso-Ricci, Francesca Dionisio, Danilo Pellin, Stefania Giannelli, Luca Biasco

Nat Med· November 2018

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Successful hematopoietic stem cell mobilization and apheresis collection using plerixafor alone in sickle cell patients.
Erica B Esrick, John P Manis, Heather Daley, Cristina Baricordi, Hélène Trébéden-Negre, Luca Biasco

Blood Adv· October 2018

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Analyzing the Genotoxicity of Retroviral Vectors in Hematopoietic Cell Gene Therapy.
Luca Biasco, Michael Rothe, Hildegard Büning, Axel Schambach

Mol Ther Methods Clin Dev· March 2018

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Preclinical Efficacy and Safety Evaluation of Hematopoietic Stem Cell Gene Therapy in a Mouse Model of MNGIE.
Rana Yadak, Raquel Cabrera-Pérez, Javier Torres-Torronteras, Marianna Bugiani, Joost C Haeck, Luca Biasco

Mol Ther Methods Clin Dev· March 2018

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Integration Site Analysis in Gene Therapy Patients: Expectations and Reality.
Luca Biasco

Hum Gene Ther· December 2017

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Current Approaches and Future Perspectives for In Vivo Clonal Tracking of Hematopoietic Cells.
Serena Scala, Lorena Leonardelli, Luca Biasco

Curr Gene Ther· October 2017

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Multiparametric Whole Blood Dissection: A one-shot comprehensive picture of the human hematopoietic system.
Luca Basso-Ricci, Serena Scala, Raffaella Milani, Maddalena Migliavacca, Attilio Rovelli, Luca Biasco

Cytometry A· October 2017

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Integrating Vectors for Gene Therapy and Clonal Tracking of Engineered Hematopoiesis.
Luca Biasco, Michael Rothe, Juliane W Schott, Axel Schambach

Hematol Oncol Clin North Am· October 2017

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In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution Phases.
Luca Biasco, Danilo Pellin, Serena Scala, Francesca Dionisio, Luca Basso-Ricci

Cell Stem Cell· July 2016

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Safety of gene therapy: new insights to a puzzling case.
Michael Rothe, Axel Schambach, Luca Biasco

Curr Gene Ther· July 2015

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In vivo tracking of T cells in humans unveils decade-long survival and activity of genetically modified T memory stem cells.
Luca Biasco, Serena Scala, Luca Basso Ricci, Francesca Dionisio, Cristina Baricordi

Sci Transl Med· February 2015

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