Publications by authors named "Luca Scorrano"

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A guide to characterizing the dynamic mitochondria-endoplasmic reticulum contact sites.
Antigoni Diokmetzidou, Luca Scorrano

FEBS J· December 2025

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Increased mitochondrial fusion via systemic OPA1 overexpression promotes dyslipidemia and atherosclerosis in LDLR deficient mice.
Lorenzo Da Dalt, Francesca Fantini, Giulia Giancane, Annalisa Moregola, Silvia Roda, Luca Scorrano

Mol Metab· December 2025

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Key challenges and recommendations for defining organelle membrane contact sites.
Tito Calì, Emmanuelle M Bayer, Emily R Eden, György Hajnóczky, Benoit Kornmann, Luca Scorrano

Nat Rev Mol Cell Biol· October 2025

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Small-molecule OPA1 inhibitors reverse mitochondrial adaptations to overcome therapy resistance in acute myeloid leukemia.
Sofia La Vecchia, Saurav Doshi, Petros Antonoglou, Tanima Kundu, Wafa Al Santli, Luca Scorrano

Sci Adv· October 2025

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Author Correction: Endoplasmic reticulum-mitochondria contacts are prime hotspots of phospholipid peroxidation driving ferroptosis.
Maria Livia Sassano, Yulia Y Tyurina, Antigoni Diokmetzidou, Ellen Vervoort, Vladimir A Tyurin, Luca Scorrano

Nat Cell Biol· September 2025

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Opantimirs: A class of antagonizing microRNAs that upregulate Opa1 and improve mitochondrial and disuse myopathies.
Andre Djalalvandi, Keisuke Takeda, Francesca Grespi, Hualin Fan, Tiago Branco Fonseca, Luca Scorrano

Cell Rep Med· August 2025

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Iron Lion ZIPion: ZIP13 Zips Iron to Heart Mitochondria.
Hualin Fan, Luca Scorrano

Circ Res· August 2025

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Small molecule OPA1 inhibitors amplify cytochrome c release and reverse cancer cells resistance to Bcl-2 inhibitors.
Anna Pellattiero, Charlotte Quirin, Federico Magrin, Mattia Sturlese, Alberto Fracasso, Luca Scorrano

Sci Adv· July 2025

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Metastatic breast cancer cells are selectively dependent on the mitochondrial cristae-shaping protein OPA1.
Antigoni Diokmetzidou, Aurora Maracani, Anna Pellattiero, Mauricio Cardenas-Rodriguez, Erwan A Rivière, Luca Scorrano

Cell Death Dis· July 2025

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Endoplasmic reticulum-mitochondria contacts are prime hotspots of phospholipid peroxidation driving ferroptosis.
Maria Livia Sassano, Yulia Y Tyurina, Antigoni Diokmetzidou, Ellen Vervoort, Vladimir A Tyurin, Luca Scorrano

Nat Cell Biol· June 2025

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Mitochondria-membranous organelle contacts at a glance.
Antigoni Diokmetzidou, Luca Scorrano

J Cell Sci· May 2025

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MARIGOLD and MitoCIAO, two searchable compendia to visualize and functionalize protein complexes during mitochondrial remodeling.
Giovanni Rigoni, Enrique Calvo, Christina Glytsou, Marta Carro-Alvarellos, Masafumi Noguchi, Luca Scorrano

Cell Metab· April 2025

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Remodeling of Mitochondria-Endoplasmic Reticulum Contact Sites Accompanies LUHMES Differentiation.
Emad Norouzi Esfahani, Tomas Knedlik, Sang Hun Shin, Ana Paula Magalhães Rebelo, Agnese De Mario, Luca Scorrano

Biomolecules· January 2025

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Glutamine sensing licenses cholesterol synthesis.
Bruna Martins Garcia, Philipp Melchinger, Tania Medeiros, Sebastian Hendrix, Kavan Prabhu, Luca Scorrano

EMBO J· December 2024

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Sweetening mitochondria: Hexokinase shields mitochondria from fission when glucose is low.
Antigoni Diokmetzidou, Luca Scorrano

Mol Cell· July 2024

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The interplay between mitochondrial dynamics and autophagy: From a key homeostatic mechanism to a driver of pathology.
Alice Lacombe, Luca Scorrano

Semin Cell Dev Biol· April 2024

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The inhibition of inner mitochondrial fusion in hepatocytes reduces non-alcoholic fatty liver and improves metabolic profile during obesity by modulating bile acid conjugation.
Lorenzo Da Dalt, Annalisa Moregola, Monika Svecla, Silvia Pedretti, Francesca Fantini, Luca Scorrano

Cardiovasc Res· February 2024

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Activation of Ca phosphatase Calcineurin regulates Parkin translocation to mitochondria and mitophagy in flies.
Elena Marchesan, Alice Nardin, Sofia Mauri, Greta Bernardo, Vivek Chander, Luca Scorrano

Cell Death Differ· February 2024

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A RalA between high-fat diet and mitochondrial shape.
Ludovica Zambello, Luca Scorrano

Nat Metab· February 2024

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Correction: Cisplatin resistance can be curtailed by blunting Bnip3-mediated mitochondrial autophagy.
Caterina Vianello, Veronica Cocetta, Daniela Catanzaro, Gerald W Dorn, Angelo De Milito, Luca Scorrano

Cell Death Dis· January 2024

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Targeting mitochondrial shape: at the heart of cardioprotection.
Sauri Hernandez-Resendiz, Aishwarya Prakash, Sze Jie Loo, Martina Semenzato, Kroekkiat Chinda, Luca Scorrano

Basic Res Cardiol· November 2023

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IL-12/15/18-induced cell death and mitochondrial dynamics of human NK cells.
Iñigo Terrén, Víctor Sandá, Ainhoa Amarilla-Irusta, Ainara Lopez-Pardo, Arrate Sevilla, Luca Scorrano

Front Immunol· August 2023

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Correction: Cisplatin resistance can be curtailed by blunting Bnip3-mediated mitochondrial autophagy.
Caterina Vianello, Veronica Cocetta, Daniela Catanzaro, Gerald W Dorn, Angelo De Milito, Luca Scorrano

Cell Death Dis· August 2023

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Correction: Cisplatin resistance can be curtailed by blunting Bnip3-mediated mitochondrial autophagy.
Caterina Vianello, Veronica Cocetta, Daniela Catanzaro, Gerald W Dorn, Angelo De Milito, Luca Scorrano

Cell Death Dis· August 2023

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Splice variants of mitofusin 2 shape the endoplasmic reticulum and tether it to mitochondria.
Déborah Naón, María Isabel Hernández-Alvarez, Satoko Shinjo, Milosz Wieczor, Saska Ivanova, Luca Scorrano

Science· June 2023

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