Publications by authors named "Lucas B Pontel"

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Emerging mechanisms underlying formaldehyde toxicity and response.
Marta Valverde-Santiago, Lucas B Pontel

Mol Cell· June 2025

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The SASP factor IL-6 sustains cell-autonomous senescent cells via a cGAS-STING-NFκB intracrine senescent noncanonical pathway.
Florencia Herbstein, Melanie Sapochnik, Alejandra Attorresi, Cora Pollak, Sergio Senin, Lucas B Pontel

Aging Cell· October 2024

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Distinct DNA repair mechanisms prevent formaldehyde toxicity during development, reproduction and aging.
Matthias Rieckher, Christian Gallrein, Natividad Alquezar-Artieda, Nour Bourached-Silva, Pavana Lakshmi Vaddavalli, Lucas B Pontel

Nucleic Acids Res· August 2024

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Formaldehyde regulates -adenosylmethionine biosynthesis and one-carbon metabolism.
Vanha N Pham, Kevin J Bruemmer, Joel D W Toh, Eva J Ge, Logan Tenney, Lucas B Pontel

Science· November 2023

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UHPLC-HRMS-Based Analysis of S-Hydroxymethyl-Glutathione, GSH, and GSSG in Human Cells.
María Eugenia Monge, Manuela R Martinefski, Mariela Bollini, Lucas B Pontel

Methods Mol Biol· June 2023

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Acute lymphoblastic leukemia necessitates GSH-dependent ferroptosis defenses to overcome FSP1-epigenetic silencing.
Lucas B Pontel, Alberto Bueno-Costa, Agustín E Morellato, Juliana Carvalho Santos, Gaël Roué

Redox Biol· September 2022

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Endogenous formaldehyde scavenges cellular glutathione resulting in redox disruption and cytotoxicity.
Carla Umansky, Agustín E Morellato, Matthias Rieckher, Marco A Scheidegger, Manuela R Martinefski, Lucas B Pontel

Nat Commun· February 2022

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The toxic side of one-carbon metabolism and epigenetics.
Agustín E Morellato, Carla Umansky, Lucas B Pontel

Redox Biol· April 2021

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Illuminating cellular formaldehyde.
Carla Umansky, Agustín E Morellato, Lucas B Pontel

Nat Commun· January 2021

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Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans.
Felix A Dingler, Meng Wang, Anfeng Mu, Christopher L Millington, Nina Oberbeck, Lucas B Pontel

Mol Cell· December 2020

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Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism.
Guillermo Burgos-Barragan, Niek Wit, Johannes Meiser, Felix A Dingler, Matthias Pietzke, Lucas B Pontel

Nature· August 2017

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Erratum: Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism.
Guillermo Burgos-Barragan, Niek Wit, Johannes Meiser, Felix A Dingler, Matthias Pietzke, Lucas B Pontel

Nature· August 2017

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Development of a General Aza-Cope Reaction Trigger Applied to Fluorescence Imaging of Formaldehyde in Living Cells.
Kevin J Bruemmer, Ryan R Walvoord, Thomas F Brewer, Guillermo Burgos-Barragan, Niek Wit, Lucas B Pontel

J Am Chem Soc· April 2017

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Xpf suppresses the mutagenic consequences of phagocytosis in Dictyostelium.
Lucas B Pontel, Judith Langenick, Ivan V Rosado, Xiao-Yin Zhang, David Traynor

J Cell Sci· December 2016

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Compartment and signal-specific codependence in the transcriptional control of Salmonella periplasmic copper homeostasis.
Alejandro Pezza, Lucas B Pontel, Carolina López, Fernando C Soncini

Proc Natl Acad Sci U S A· October 2016

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Endogenous Formaldehyde Is a Hematopoietic Stem Cell Genotoxin and Metabolic Carcinogen.
Lucas B Pontel, Ivan V Rosado, Guillermo Burgos-Barragan, Juan I Garaycoechea, Rui Yu

Mol Cell· October 2015

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A dimerization interface mediated by functionally critical residues creates interfacial disulfide bonds and copper sites in CueP.
Luciano A Abriata, Lucas B Pontel, Alejandro J Vila, Matteo Dal Peraro, Fernando C Soncini

J Inorg Biochem· November 2014

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Identification of a Salmonella ancillary copper detoxification mechanism by a comparative analysis of the genome-wide transcriptional response to copper and zinc excess.
Lucas B Pontel, Nadia L Scampoli, Steffen Porwollik, Susana K Checa, Michael McClelland

Microbiology (Reading)· August 2014

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Copper stress targets the rcs system to induce multiaggregative behavior in a copper-sensitive Salmonella strain.
Lucas B Pontel, Alejandro Pezza, Fernando C Soncini

J Bacteriol· December 2010

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Alternative periplasmic copper-resistance mechanisms in Gram negative bacteria.
Lucas B Pontel, Fernando C Soncini

Mol Microbiol· July 2009

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Regulation of magnesium homeostasis in Salmonella: Mg(2+) targets the mgtA transcript for degradation by RNase E.
Silvana V Spinelli, Lucas B Pontel, Eleonora García Véscovi, Fernando C Soncini

FEMS Microbiol Lett· March 2008

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GolS controls the response to gold by the hierarchical induction of Salmonella-specific genes that include a CBA efflux-coding operon.
Lucas B Pontel, María E Pérez Audero, Martín Espariz, Susana K Checa, Fernando C Soncini

Mol Microbiol· November 2007

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Dissecting the Salmonella response to copper.
Martín Espariz, Susana K Checa, María E Pérez Audero, Lucas B Pontel, Fernando C Soncini

Microbiology (Reading)· September 2007

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