Publications by authors named "Ludger Scheja"

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Purinergic adipocyte-macrophage crosstalk promotes degeneration of thermogenic brown adipose tissue.
Michelle Y Jaeckstein, Alexander W Fischer, Björn Rissiek, Tobias Staehler, Markus Heine, Ludger Scheja

EMBO Rep· December 2025

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Fructose uptake by brown adipose tissue is independent of carbohydrate response element-binding protein and does not cause elevated lipogenesis.
Janina Behrens, Marceline Manka Fuh, Daniel T Haas, Michelle Y Jaeckstein, Markus Heine, Ludger Scheja

Acta Biochim Biophys Sin (Shanghai)· December 2025

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Single-nucleus mRNA-sequencing reveals dynamics of lipogenic and thermogenic adipocyte populations in murine brown adipose tissue in response to cold exposure.
Janina Behrens, Tongtong Wang, Christoph Kilian, Anna Worthmann, Mark A Herman, Ludger Scheja

Mol Metab· November 2025

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An efficient AAV vector system of Rec2 serotype for intravenous injection to study metabolism in brown adipocytes in vivo.
Janina Behrens, Ingke Braren, Michelle Y Jaeckstein, Luka Lilie, Markus Heine, Ludger Scheja

Mol Metab· October 2024

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From Planning Stage Towards FAIR Data: A Practical Metadatasheet For Biomedical Scientists.
Lea Seep, Stephan Grein, Iva Splichalova, Danli Ran, Mickel Mikhael, Ludger Scheja

Sci Data· May 2024

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Fatty acid synthesis suppresses dietary polyunsaturated fatty acid use.
Anna Worthmann, Julius Ridder, Sharlaine Y L Piel, Ioannis Evangelakos, Melina Musfeldt, Ludger Scheja

Nat Commun· January 2024

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Loss of hepatic SMLR1 causes hepatosteatosis and protects against atherosclerosis due to decreased hepatic VLDL secretion.
Willemien van Zwol, Antoine Rimbert, Justina C Wolters, Marieke Smit, Vincent W Bloks, Ludger Scheja

Hepatology· November 2023

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The lysosomal LAMTOR / Ragulator complex is essential for nutrient homeostasis in brown adipose tissue.
Gudrun Liebscher, Nemanja Vujic, Renate Schreiber, Markus Heine, Caroline Krebiehl, Ludger Scheja

Mol Metab· May 2023

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TREM2 Regulates the Removal of Apoptotic Cells and Inflammatory Processes during the Progression of NAFLD.
Imke Liebold, Simon Meyer, Markus Heine, Anastasia Kuhl, Jennifer Witt, Ludger Scheja

Cells· January 2023

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Role of Endothelial Cell Lipoprotein Lipase for Brown Adipose Tissue Lipid and Glucose Handling.
Ellen Thiemann, Gerburg K Schwaerzer, Ioannis Evangelakos, Marceline M Fuh, Michelle Y Jaeckstein, Ludger Scheja

Front Physiol· March 2022

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Novel Adipose Tissue Targets to Prevent and Treat Atherosclerosis.
Ludger Scheja, Joerg Heeren

Handb Exp Pharmacol· February 2022

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Replication of SARS-CoV-2 in adipose tissue determines organ and systemic lipid metabolism in hamsters and humans.
Martin Zickler, Stephanie Stanelle-Bertram, Sandra Ehret, Fabian Heinrich, Philine Lange, Ludger Scheja

Cell Metab· January 2022

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Isthmin 1 - a novel insulin-like adipokine.
Joerg Heeren, Ludger Scheja

Nat Rev Endocrinol· December 2021

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Oxysterol 7-α Hydroxylase (CYP7B1) Attenuates Metabolic-Associated Fatty Liver Disease in Mice at Thermoneutrality.
Ioannis Evangelakos, Dorothee Schwinge, Anna Worthmann, Clara John, Niklas Roeder, Ludger Scheja

Cells· October 2021

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Metabolic-associated fatty liver disease and lipoprotein metabolism.
Joerg Heeren, Ludger Scheja

Mol Metab· August 2021

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TFEB deficiency attenuates mitochondrial degradation upon brown adipose tissue whitening at thermoneutrality.
Frederike Sass, Christian Schlein, Michelle Y Jaeckstein, Paul Pertzborn, Michaela Schweizer, Ludger Scheja

Mol Metab· May 2021

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Lysosomal lipoprotein processing in endothelial cells stimulates adipose tissue thermogenic adaptation.
Alexander W Fischer, Michelle Y Jaeckstein, Kristina Gottschling, Markus Heine, Frederike Sass, Ludger Scheja

Cell Metab· March 2021

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Endothelial Lipase Is Involved in Cold-Induced High-Density Lipoprotein Turnover and Reverse Cholesterol Transport in Mice.
Nicola Schaltenberg, Clara John, Markus Heine, Friederike Haumann, Franz Rinninger, Ludger Scheja

Front Cardiovasc Med· March 2021

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Endogenous Fatty Acid Synthesis Drives Brown Adipose Tissue Involution.
Christian Schlein, Alexander W Fischer, Frederike Sass, Anna Worthmann, Klaus Tödter, Ludger Scheja

Cell Rep· January 2021

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Brown adipose tissue lipoprotein and glucose disposal is not determined by thermogenesis in uncoupling protein 1-deficient mice.
Alexander W Fischer, Janina Behrens, Frederike Sass, Christian Schlein, Markus Heine, Ludger Scheja

J Lipid Res· November 2020

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Therapeutic Targeting of Myeloperoxidase Attenuates NASH in Mice.
Anja Christina Koop, Nina Doreen Thiele, David Steins, Erik Michaëlsson, Malte Wehmeyer, Ludger Scheja

Hepatol Commun· October 2020

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Inulin Supplementation Disturbs Hepatic Cholesterol and Bile Acid Metabolism Independent from Housing Temperature.
Mira J Pauly, Julia K Rohde, Clara John, Ioannis Evangelakos, Anja Christina Koop, Ludger Scheja

Nutrients· October 2020

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A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism.
Marta Pradas-Juni, Nils R Hansmeier, Jenny C Link, Elena Schmidt, Bjørk Ditlev Larsen, Ludger Scheja

Nat Commun· January 2020

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The endocrine function of adipose tissues in health and cardiometabolic disease.
Ludger Scheja, Joerg Heeren

Nat Rev Endocrinol· September 2019

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