Publications by authors named "Lukas Heukamp"

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Editorial Expression of Concern: Rationale for co-targeting IGF-1R and ALK in ALK fusion-positive lung cancer.
Christine M Lovly, Nerina T McDonald, Heidi Chen, Sandra Ortiz-Cuaran, Lukas C Heukamp

Nat Med· December 2025

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Intergroup-statement: statement of the german ovarian cancer commission, the North-Eastern German Society of gynecological Oncology (NOGGO), AGO Austria and AGO Swiss regarding the use of homologous repair deficiency (HRD) assays in advanced ovarian cancer.
Lukas Chinczewski, Philipp Harter, Lukas Heukamp, Doris Mayr, Christoph Grimm

Arch Gynecol Obstet· May 2025

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Detection of Mutations in Tissue and Liquid Biopsy with Novel Next-Generation Sequencing and Digital Droplet PCR Assays: Insights from Multi-Center Real Life Data of Almost 6000 Patients.
Srushti Borkar, Fenja Markus, Agnes Oetting, Stefanie Schmidt, Christine Vössing, Lukas C Heukamp

Cancers (Basel)· April 2025

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Targeting KDM1A in Neuroblastoma with NCL-1 Induces a Less Aggressive Phenotype and Suppresses Angiogenesis.
Annika Sprüssel, Takayoshi Suzuki, Naoki Miyata, Kathy Astrahantseff, Annabell Szymansky, Lukas C Heukamp

J Clin Med· October 2024

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Cell-free tumor DNA, CA125 and HE4 for the objective assessment of tumor burden in patients with advanced high-grade serous ovarian cancer.
Florian Heitz, Sotirios Lakis, Philipp Harter, Sebastian Heikaus, Jalid Sehouli, Lukas C Heukamp

PLoS One· July 2024

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Intracranial response to capmatinib after progression on crizotinib in a patient with exon 14 skipping non-small cell lung cancer-a case report.
Balázs Jóri, Otto Bundschuh, Markus Falk, Lukas C Heukamp, Alexander Kluge

Transl Lung Cancer Res· July 2024

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High Concordance of Different Assays in the Determination of Homologous Recombination Deficiency-Associated Genomic Instability in Ovarian Cancer.
Nicole Pfarr, Karin von Schwarzenberg, Dario Zocholl, Sabine Merkelbach-Bruse, Janna Siemanowski, Lukas C Heukamp

JCO Precis Oncol· March 2024

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Evaluation of the Prognostic Impact of SP263-Evaluated PD-L1 Expression in Patients with Stage III Non-Small Cell Lung Cancer (NSLC) Treated with Radio-Chemotherapy.
Jan Nicolai Wagner, Julia Roeper, Lukas Heukamp, Markus Falk, Kay Willborn

Biomedicines· March 2024

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Synaptopodin-2 Isoforms Have Specific Binding Partners and Display Distinct, Muscle Cell Type-Specific Expression Patterns.
Keerthika Lohanadan, Marvin Assent, Anja Linnemann, Julia Schuld, Lukas C Heukamp

Cells· December 2023

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The Combined Therapy of Cabozantinib, Crizotinib, and Osimertinib in a Lung Cancer Patient with Acquired MET Amplification and Resistance Mutations.
Balázs Jóri, Christine Vössing, Judith Pirngruber, Eva Maria Willing, Kathrin Arndt, Lukas C Heukamp

Curr Oncol· September 2023

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Development of the NOGGO GIS v1 Assay, a Comprehensive Hybrid-Capture-Based NGS Assay for Therapeutic Stratification of Homologous Repair Deficiency Driven Tumors and Clinical Validation.
Eva-Maria Willing, Claudia Vollbrecht, Christine Vössing, Peggy Weist, Simon Schallenberg, Lukas C Heukamp

Cancers (Basel)· June 2023

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Response to (K)RAS and EGFR Inhibition in a Patient With -Mutated Rectal Cancer.
Lino Möhrmann, Ani Cuberi, Sascha Brückmann, Sebastian Stasik, Lukas C Heukamp

JCO Precis Oncol· May 2023

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Acquired G2032R Resistance Mutation in ROS1 to Lorlatinib Therapy Detected with Liquid Biopsy.
Balázs Jóri, Markus Falk, Iris Hövel, Peggy Weist, Markus Tiemann, Lukas C Heukamp

Curr Oncol· September 2022

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The ADP-Ribosylation Factor 4d Restricts Regulatory T-Cell Induction via Control of IL-2 Availability.
Bernd Geers, Julia Hagenstein, Jessica Endig, Hanna Ulrich, Laura Fleig, Lukas Heukamp

Cells· August 2022

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Notch1 Deficiency Induces Tumor Cell Accumulation Inside the Bronchiolar Lumen and Increases TAZ Expression in an Autochthonous Driven Lung Cancer Mouse Model.
Lydia Meder, Alexandra Florin, Luka Ozretić, Marieke Nill, Mirjam Koker, Lukas C Heukamp

Pathol Oncol Res· January 2022

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co-mutations as an independent prognostic factor in 2nd and further line therapy- mutated non-small cell lung cancer IV patients treated with osimertinib.
Julia Roeper, Petros Christopoulos, Markus Falk, Lukas C Heukamp, Markus Tiemann

Transl Lung Cancer Res· January 2022

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Smad7 Deficiency in Myeloid Cells Does Not Affect Liver Injury, Inflammation or Fibrosis after Chronic CCl Exposure in Mice.
Ludmilla Unrau, Jessica Endig, Diane Goltz, Paulina Sprezyna, Hanna Ulrich, Lukas Carl Heukamp

Int J Mol Sci· October 2021

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NOX2 Deficiency Permits Sustained Survival of in Macrophages and Contributes to Severity of Infection.
Bettina Tosetti, Beate Ward, Daniela Grumme, Marc Herb, Michael Schramm, Lukas C Heukamp

Front Immunol· September 2021

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Corrigendum to "Biomarker testing in non-small cell lung cancer in routine care: Analysis of the first 3,717 patients in the German prospective, observational, nation-wide CRISP registry (AIO-TRK-0315)" [Lung Cancer 152 (2021) 174-184].
Frank Griesinger, Wilfried Eberhardt, Arnd Nusch, Marcel Reiser, Mark-Oliver Zahn, Lukas C Heukamp

Lung Cancer· July 2021

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Neuroblastoma Risk Assessment and Treatment Stratification with Hybrid Capture-Based Panel Sequencing.
Annabell Szymansky, Louisa-Marie Kruetzfeldt, Lukas C Heukamp, Falk Hertwig, Jessica Theissen

J Pers Med· July 2021

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Comparison of Resistance Spectra after First and Second Line Osimertinib Treatment Detected by Liquid Biopsy.
Balázs Jóri, Stefanie Schatz, Len Kaller, Bettina Kah, Julia Roeper, Lukas C Heukamp

Cancers (Basel)· June 2021

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BRAF mutations and BRAF mutation functional class have no negative impact on the clinical outcome of advanced NSCLC and associate with susceptibility to immunotherapy.
Marcel Wiesweg, Cedric Preuß, Julia Roeper, Martin Metzenmacher, Wilfried Eberhardt, Lukas Heukamp

Eur J Cancer· May 2021

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KRAS G12C-mutated advanced non-small cell lung cancer: A real-world cohort from the German prospective, observational, nation-wide CRISP Registry (AIO-TRK-0315).
Martin Sebastian, Wilfried E E Eberhardt, Petra Hoffknecht, Martin Metzenmacher, Thomas Wehler, Lukas C Heukamp

Lung Cancer· April 2021

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Lorlatinib in pretreated ALK- or ROS1-positive lung cancer and impact of TP53 co-mutations: results from the German early access program.
Nikolaj Frost, Petros Christopoulos, Diego Kauffmann-Guerrero, Jan Stratmann, Richard Riedel, Lukas Heukamp

Ther Adv Med Oncol· February 2021

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Inflammatory myofibroblastic tumour of the central airways: treatment and molecular analysis.
Aparna Iyer, Teodora Radonic, Lukas C Heukamp, Erik Thunnissen, Johannes M A Daniels

ERJ Open Res· January 2021

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