Publications by authors named "Luke A Miles"

Claim this Profile
T
The structural foundations of anti-amyloid-β immunotherapies: Unravelling antibody-antigen interactions in Alzheimer's disease treatment.
Luke A Miles, Colin L Masters

J Alzheimers Dis· September 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Correction: Abeta targets of the biosimilar antibodies of Bapineuzumab, Crenezumab, Solanezumab in comparison to an antibody against N-truncted Abeta in sporadic Alzheimer disease cases and mouse models.
Yvonne Bouter, Jose Socrates Lopez Noguerola, Petra Tucholla, Gabriela A N Crespi, Michael W Parker, Luke A Miles

Acta Neuropathol· March 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Pre-targeting amyloid-β with antibodies for potential molecular imaging of Alzheimer's disease.
Katherine A Morgan, Michael de Veer, Luke A Miles, Cormac A A Kelderman, Catriona A McLean

Chem Commun (Camb)· February 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Associations of plasma soluble CD22 levels with brain amyloid burden and cognitive decline in Alzheimer's disease.
Xian-Le Bu, Pu-Yang Sun, Dong-Yu Fan, Jun Wang, Hao-Lun Sun, Luke A Miles

Sci Adv· April 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Genomics of Alzheimer's disease implicates the innate and adaptive immune systems.
Yihan Li, Simon M Laws, Luke A Miles, James S Wiley, Xin Huang

Cell Mol Life Sci· December 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Small Molecule Binding to Alzheimer Risk Factor CD33 Promotes Aβ Phagocytosis.
Luke A Miles, Stefan J Hermans, Gabriela A N Crespi, Jonathan H Gooi, Larissa Doughty

iScience· September 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Promiscuous DNA-binding of a mutant zinc finger protein corrupts the transcriptome and diminishes cell viability.
Kevin R Gillinder, Melissa D Ilsley, Danitza Nébor, Ravi Sachidanandam, Mathieu Lajoie, Luke A Miles

Nucleic Acids Res· February 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Ex vivo O-labeling mass spectrometry identifies a peripheral amyloid β clearance pathway.
Erik Portelius, Niklas Mattsson, Josef Pannee, Henrik Zetterberg, Magnus Gisslén, Luke A Miles

Mol Neurodegener· February 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Transitional changes in the CRP structure lead to the exposure of proinflammatory binding sites.
David Braig, Tracy L Nero, Hans-Georg Koch, Benedict Kaiser, Xiaowei Wang, Luke A Miles

Nat Commun· January 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Abeta targets of the biosimilar antibodies of Bapineuzumab, Crenezumab, Solanezumab in comparison to an antibody against N‑truncated Abeta in sporadic Alzheimer disease cases and mouse models.
Yvonne Bouter, Jose Socrates Lopez Noguerola, Petra Tucholla, Gabriela A N Crespi, Michael W Parker, Luke A Miles

Acta Neuropathol· November 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Do current therapeutic anti-Aβ antibodies for Alzheimer's disease engage the target?
Andrew D Watt, Gabriela A N Crespi, Russell A Down, David B Ascher, Adam Gunn, Luke A Miles

Acta Neuropathol· August 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Molecular basis for mid-region amyloid-β capture by leading Alzheimer's disease immunotherapies.
Gabriela A N Crespi, Stefan J Hermans, Michael W Parker, Luke A Miles

Sci Rep· April 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Anti-Aβ antibody target engagement: a response to Siemers et al.
Andrew D Watt, Gabriela A N Crespi, Russell A Down, David B Ascher, Adam Gunn, Luke A Miles

Acta Neuropathol· October 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Crystallization and preliminary X-ray diffraction analysis of the Fab portion of the Alzheimer's disease immunotherapy candidate bapineuzumab complexed with amyloid-β.
Gabriela A N Crespi, David B Ascher, Michael W Parker, Luke A Miles

Acta Crystallogr F Struct Biol Commun· March 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Bapineuzumab captures the N-terminus of the Alzheimer's disease amyloid-beta peptide in a helical conformation.
Luke A Miles, Gabriela A N Crespi, Larissa Doughty, Michael W Parker

Sci Rep· August 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structural approaches to probing metal interaction with proteins.
Lorien J Parker, David B Ascher, Chen Gao, Luke A Miles, Hugh H Harris

J Inorg Biochem· October 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
An Escherichia coli cell-free system for recombinant protein synthesis on a milligram scale.
Luke A Miles, Gabriela A N Crespi, Sen Han, Andrew F Hill, Michael W Parker

Methods Mol Biol· October 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Solid-phase synthesis of homodimeric peptides: preparation of covalently-linked dimers of amyloid beta peptide.
W Mei Kok, Denis B Scanlon, John A Karas, Luke A Miles, Deborah J Tew

Chem Commun (Camb)· November 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Cu2+ binding modes of recombinant alpha-synuclein--insights from EPR spectroscopy.
Simon C Drew, Su Ling Leong, Chi L L Pham, Deborah J Tew, Colin L Masters, Luke A Miles

J Am Chem Soc· June 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Crystallization and preliminary X-ray diffraction analysis of the Fab fragment of WO2, an antibody specific for the Abeta peptides associated with Alzheimer's disease.
Kwok S Wun, Luke A Miles, Gabriela A N Crespi, Kaye Wycherley, David B Ascher

Acta Crystallogr Sect F Struct Biol Cryst Commun· May 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Copper binding to the Alzheimer's disease amyloid precursor protein.
Geoffrey K-W Kong, Luke A Miles, Gabriela A N Crespi, Craig J Morton, Hooi Ling Ng

Eur Biophys J· March 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope.
Luke A Miles, Kwok S Wun, Gabriela A N Crespi, Michelle T Fodero-Tavoletti, Denise Galatis

J Mol Biol· March 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structures of phage-display peptides that bind to the malarial surface protein, apical membrane antigen 1, and block erythrocyte invasion.
David W Keizer, Luke A Miles, Felomena Li, Margie Nair, Robin F Anders

Biochemistry· August 2003

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structure of a novel P-superfamily spasmodic conotoxin reveals an inhibitory cystine knot motif.
Luke A Miles, Catherine Y Dy, Jake Nielsen, Kevin J Barnham, Mark G Hinds

J Biol Chem· November 2002

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis