Publications by authors named "Luke A O'Neill"

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Author Correction: Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways.
Naziia Kurmasheva, Aida Said, Boaz Wong, Priscilla Kinderman, Xiaoying Han, Luke A O'Neill

Nat Commun· December 2024

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Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways.
Naziia Kurmasheva, Aida Said, Boaz Wong, Priscilla Kinderman, Xiaoying Han, Luke A O'Neill

Nat Commun· May 2024

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Two for the price of one: itaconate and its derivatives as an anti-infective and anti-inflammatory immunometabolite.
Anne F McGettrick, Luke Aj O'Neill

Curr Opin Immunol· February 2023

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Choice of SARS-CoV-2 diagnostic test: challenges and key considerations for the future.
Fausto Baldanti, Nirmal K Ganguly, Guiqiang Wang, Martin Möckel, Luke A O'Neill

Crit Rev Clin Lab Sci· November 2022

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Signaling metabolite L-2-hydroxyglutarate activates the transcription factor HIF-1α in lipopolysaccharide-activated macrophages.
Niamh C Williams, Dylan G Ryan, Ana S H Costa, Evanna L Mills, Mark P Jedrychowski, Luke A O'Neill

J Biol Chem· February 2022

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The role of itaconate in host defense and inflammation.
Christian G Peace, Luke Aj O'Neill

J Clin Invest· January 2022

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Immune-mediated inflammation across disease boundaries: breaking down research silos.
Christopher D Buckley, Lorna Chernajovsky, Yuti Chernajovsky, Louise K Modis, Luke A O'Neill

Nat Immunol· November 2021

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TCA cycle signalling and the evolution of eukaryotes.
Dylan G Ryan, Christian Frezza, Luke Aj O'Neill

Curr Opin Biotechnol· April 2021

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Desferrioxamine Supports Metabolic Function in Primary Human Macrophages Infected With .
James Joseph Phelan, Kate McQuaid, Colin Kenny, Karl Michael Gogan, Dónal J Cox, Luke A O'Neill

Front Immunol· March 2021

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Bridging the gap - a new role for STAT3 in TLR4-mediated metabolic reprogramming.
Hauke J Weiss, Luke Aj O'Neill

Immunol Cell Biol· February 2021

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Author Correction: A guiding map for inflammation.
Mihai G Netea, Frances Balkwill, Michel Chonchol, Fabio Cominelli, Marc Y Donath, Luke A O'Neill

Nat Immunol· February 2021

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ACLY-matizing Macrophages to Histone Modification during Immunometabolic Reprogramming.
Niamh C Williams, Luke A O'Neill

Trends Immunol· February 2020

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Specific Inhibition of the NLRP3 Inflammasome as an Antiinflammatory Strategy in Cystic Fibrosis.
Oliver J McElvaney, Zbigniew Zaslona, Katrin Becker-Flegler, Eva M Palsson-McDermott, Fiona Boland, Luke A O'Neill

Am J Respir Crit Care Med· December 2019

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Malonylation of GAPDH is an inflammatory signal in macrophages.
Silvia Galván-Peña, Richard G Carroll, Carla Newman, Elizabeth C Hinchy, Eva Palsson-McDermott, Luke A O'Neill

Nat Commun· January 2019

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Coupling Krebs cycle metabolites to signalling in immunity and cancer.
Dylan G Ryan, Michael P Murphy, Christian Frezza, Hiran A Prag, Edward T Chouchani, Luke A O'Neill

Nat Metab· January 2019

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A Defective Pentose Phosphate Pathway Reduces Inflammatory Macrophage Responses during Hypercholesterolemia.
Jeroen Baardman, Sanne G S Verberk, Koen H M Prange, Michel van Weeghel, Saskia van der Velden, Luke A O'neill

Cell Rep· November 2018

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Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice.
Richard Gordon, Eduardo A Albornoz, Daniel C Christie, Monica R Langley, Vinod Kumar, Luke A O'Neill

Sci Transl Med· October 2018

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Nrf2 negatively regulates STING indicating a link between antiviral sensing and metabolic reprogramming.
David Olagnier, Aske M Brandtoft, Camilla Gunderstofte, Nikolaj L Villadsen, Christian Krapp, Luke A O'Neill

Nat Commun· August 2018

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Dimethyl fumarate: targeting glycolysis to treat MS.
Stefano Angiari, Luke A O'Neill

Cell Res· June 2018

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An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation.
Richard G Carroll, Zbigniew Zasłona, Silvia Galván-Peña, Emma L Koppe, Daniel C Sévin, Luke A O'Neill

J Biol Chem· April 2018

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Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
Evanna L Mills, Dylan G Ryan, Hiran A Prag, Dina Dikovskaya, Deepthi Menon, Luke A O'Neill

Nature· April 2018

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GOTcha: lncRNA-ACOD1 targets metabolism during viral infection.
Marah C Runtsch, Luke Aj O'Neill

Cell Res· February 2018

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Canakinumab for Atherosclerotic Disease.
Luke A O'Neill, Matthew A Cooper

N Engl J Med· January 2018

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Pyruvate Kinase M2 Is Required for the Expression of the Immune Checkpoint PD-L1 in Immune Cells and Tumors.
Eva M Palsson-McDermott, Lydia Dyck, Zbigniew Zasłona, Deepthi Menon, Anne F McGettrick, Luke A O'Neill

Front Immunol· October 2017

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A guiding map for inflammation.
Mihai G Netea, Frances Balkwill, Michel Chonchol, Fabio Cominelli, Marc Y Donath, Luke A O'Neill

Nat Immunol· July 2017

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