Publications by authors named "Luke Alvey"

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Discovery of GLPG1972/S201086, a Potent, Selective, and Orally Bioavailable ADAMTS-5 Inhibitor for the Treatment of Osteoarthritis.
Franck Brebion, Romain Gosmini, Pierre Deprez, Marie Varin, Christophe Peixoto, Luke Alvey

J Med Chem· March 2021

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Discovery of 9-Cyclopropylethynyl-2-(()-1-[1,4]dioxan-2-ylmethoxy)-6,7-dihydropyrimido[6,1-]isoquinolin-4-one (GLPG1205), a Unique GPR84 Negative Allosteric Modulator Undergoing Evaluation in a Phase II Clinical Trial.
Frédéric Labéguère, Sonia Dupont, Luke Alvey, Florilène Soulas, Gregory Newsome

J Med Chem· November 2020

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The Flexiscope: a low cost, flexible, convertible and modular microscope with automated scanning and micromanipulation.
Amy Courtney, Luke M Alvey, George O T Merces, Niamh Burke, Mark Pickering

R Soc Open Sci· March 2020

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Bands of Fontana are caused exclusively by the sinusoidal path of axons in peripheral nerves and predict axon path; evidence from rodent nerves and physical models.
Luke M Alvey, James F X Jones, Cathal Tobin-O'Brien, Mark Pickering

J Anat· February 2019

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Identification of a 4-(hydroxymethyl)diarylhydantoin as a selective androgen receptor modulator.
François Nique, Séverine Hebbe, Nicolas Triballeau, Christophe Peixoto, Jean-Michel Lefrançois, Luke Alvey

J Med Chem· October 2012

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Diversity-oriented synthesis of furo[3,2-f]chromanes with antimycobacterial activity.
Luke Alvey, Soizic Prado, Brigitte Saint-Joanis, Sylvie Michel, Michel Koch

Eur J Med Chem· June 2009

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A new synthetic access to furo[3,2-f]chromene analogues of an antimycobacterial.
Luke Alvey, Soizic Prado, Valérie Huteau, Brigitte Saint-Joanis, Sylvie Michel

Bioorg Med Chem· September 2008

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Inhibitory effects of a series of 7-substituted-indazoles toward nitric oxide synthases: particular potency of 1H-indazole-7-carbonitrile.
Betty Cottyn, Francine Acher, Booma Ramassamy, Luke Alvey, Michel Lepoivre

Bioorg Med Chem· June 2008

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Additions of PH(3) to Monosubstituted Alkenes of the Formula H(2)C=CH(CH(2))(x)()(CF(2))(y)()CF(3): Convenient, Multigram Syntheses of a Family of Partially Fluorinated Trialkylphosphines with Modulated Electronic Properties and Fluorous Phase Affinities.
Luke J. Alvey, Drew Rutherford, Jerrick J. J. Juliette, J. A. Gladysz

J Org Chem· September 1998

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