Publications by authors named "Luke O'Neill"

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Targeting complex IV to alter the tumor microenvironment and boost macrophage antitumor immunity.
Thomas Pfefer, Luke A J O'Neill

Life Metab· December 2025

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Mitochondrial glutathione transporter SLC25A40 regulates macrophage cytokine production.
Maureen Yin, Eva M Palsson-McDermott, Órlaith C Henry, Ziqian Ge, Juliana E Toller-Kawahisa, Luke A J O'Neill

Sci Rep· December 2025

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Impact of antibiotic side effects and allergies on patient adherence and attitudes: a mixed methods study in England.
Liam Michael Clayton, Catherine V Hayes, Luke O'Neill, Fionna Pursey, Libby Eastwood

BJGP Open· December 2025

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Anatomic Location of the Bowel in Different Surgical Positions: Implications for Lateral Access in Prone Single-Position Surgery.
S Harrison Farber, Robert F Rudy, James J Zhou, Nima Alan, Joseph D DiDomenico, Luke K O'Neill

Spine (Phila Pa 1976)· November 2025

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Association of operative-level segmental lordosis correction with reciprocal changes in sagittal and spinopelvic parameters after single-level lateral lumbar interbody fusion at L4-5.
Nafis B Eghrari, Jonathan J Lee, Winward Choy, Juan P Giraldo, Gabriella P Williams, Luke K O'Neill

Eur Spine J· November 2025

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In vitro protocol demonstrating five functional steps of trained immunity in mice: Implications on biomarker discovery and translational research.
Maria González-Pérez, Jana Baranda, Leticia Pérez-Rodríguez, Patricia Conde, Carlos de la Calle-Fabregat, Luke A J O'Neill

Cell Rep· October 2025

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Adenosine 2A receptor-dependent activation of AMPK represses T17 cell pathogenicity through epigenetic and metabolic reprogramming.
Gina Papadopoulou, Dimitrios Valakos, Ioanna Polydouri, Afroditi Moulara, Giannis Vatsellas, Luke A J O'Neill

Sci Signal· September 2025

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Methodologies for label free Raman microspectroscopic monitoring of viral replication processes in vitro.
Iqra Chaudary, Judit Barabas, Ultan F Power, Luke O'Neill, Hugh J Byrne

Methods· August 2025

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Lessons from Glucocorticoids, Metformin, and Dimethyl Fumarate: Could Targeting Immunometabolism Lead to Better Anti-Inflammatory Therapies?
Victoria A Evans, Luke A J O'Neill

Annu Rev Pharmacol Toxicol· July 2025

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Low Posterior Electromyographic Threshold and Functional Outcomes After L4-5 Lateral Lumbar Interbody Fusion.
Robert F Rudy, S Harrison Farber, Juan P Giraldo, Nima Alan, James J Zhou, Luke K O'Neill

Oper Neurosurg· July 2025

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Chitinase-1 inhibition attenuates metabolic dysregulation and restores homeostasis in MASH animal models.
Katarzyna Drzewicka, Katarzyna M Głuchowska, Michal Mlącki, Bartłomiej Hofman, Irina Tuszyńska, Luke A J O'Neill

Front Immunol· June 2025

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"Floating Island" Technique: Case Series of a Novel Technique for Surgical Management of Interdigitating Calcified Thoracic Disc Herniations.
Nima Alan, Luke K O'Neill, S Harrison Farber, James J Zhou, Juan P Giraldo

World Neurosurg· May 2025

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Gang of 3: How the Krebs cycle-linked metabolites itaconate, succinate, and fumarate regulate macrophages and inflammation.
Eva M Pålsson-McDermott, Luke A J O'Neill

Cell Metab· May 2025

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MAVS is a sensor of fumarate during antiviral immunity.
Yukun Min, Luke A J O'Neill

Nat Microbiol· May 2025

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4-octyl itaconate reduces human NLRP3 inflammasome constitutive activation with the cryopyrin-associated periodic syndrome p.R262W, p.D305N and p.T350M variants.
Cristina Molina-Lopez, Laura Hurtado-Navarro, Luke A J O'Neill, Pablo Pelegrin

Cell Mol Life Sci· May 2025

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Recycling dead bacteria to fuel macrophage immunometabolism.
Shane M O'Carroll, Luke A J O'Neill

Nat Immunol· April 2025

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Metabolic Reprogramming in Stromal and Immune Cells in Rheumatoid Arthritis and Osteoarthritis: Therapeutic Possibilities.
Órlaith C Henry, Luke A J O'Neill

Eur J Immunol· April 2025

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Computed Tomography Assessment of Long-Term Fusion and Subsidence for Anterior Lumbar Interbody Fusion Performed at the Lumbosacral Junction.
S Harrison Farber, Michael D White, Robert K Dugan, Luke K O'Neill, Kurt V Shaffer

Clin Spine Surg· April 2025

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Intramedullary spinal aspergillosis in an immunocompetent host with no extraspinal infection: illustrative case.
Siddhartha Srivastava, Juan P Giraldo, S Harrison Farber, Ahmad Aldeiri, Nima Alan, Luke K O'Neill

J Neurosurg Case Lessons· April 2025

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Obesity and Clinical, Radiographic, and Surgical Outcomes After Minimally Invasive Single-Level Transforaminal versus Lateral Lumbar Interbody Fusion.
Nafis B Eghrari, Jonathan J Lee, Juan P Giraldo, Winward Choy, Gabriella P Williams, Luke K O'Neill

World Neurosurg· March 2025

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Trained immunity causes myeloid cell hypercoagulability.
Aisling M Rehill, Seán McCluskey, Anna E Ledwith, Tristram A J Ryan, Betül Ünlü, Luke A J O'Neill

Sci Adv· March 2025

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Preventing and managing urinary tract infections: Exploring interventions and strategies implemented by NHS commissioning organisations in English primary care, 2017-2022.
Eirwen Sides, Donna M Lecky, Esther Taborn, Luke O'Neill, Emily Cooper

J Infect Prev· March 2025

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Metabolic reprogramming of macrophages by PKM2 promotes IL-10 production via adenosine.
Juliana Escher Toller-Kawahisa, Paula Ramos Viacava, Eva Margareta Palsson-McDermott, Daniele Carvalho Nascimento, Mariana Patricia Cervantes-Silva, Luke Anthony John O'Neill

Cell Rep· January 2025

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Mitochondrial respiratory complex III sustains IL-10 production in activated macrophages and promotes tumor-mediated immune evasion.
Alessia Zotta, Juliana Toller-Kawahisa, Eva M Palsson-McDermott, Shane M O'Carroll, Órlaith C Henry, Luke A J O'Neill

Sci Adv· January 2025

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T-Bar Angular Offset: A Novel Angle for Predicting Postoperative Coronal Balance Using Intraoperative Stitched Radiographs.
James J Zhou, S Harrison Farber, Timothy C Gooldy, Charuta G Furey, Steve S Cho, Luke K O'Neill

Oper Neurosurg· November 2024

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