Publications by authors named "Luke Springer"

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Adipose-derived leptin and complement factor D mediate osteoarthritis severity and pain.
Kelsey H Collins, Kristin L Lenz, Hope D Welhaven, Erica Ely, Luke E Springer

Sci Adv· April 2025

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Engineered self-regulating macrophages for targeted anti-inflammatory drug delivery.
Molly Klimak, Amanda Cimino, Kristin L Lenz, Luke E Springer, Kelsey H Collins

Arthritis Res Ther· November 2024

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Safety Evaluations of Rapamycin Perfluorocarbon Nanoparticles in Ovarian Tumor-Bearing Mice.
Qingyu Zhou, John C Harding, Ping Fan, Ivan Spasojevic, Attila Kovacs, Luke E Springer

Nanomaterials (Basel)· October 2024

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Mucosal signatures of pathogenic T cells in HLA-B*27+ anterior uveitis and axial spondyloarthritis.
Michael A Paley, Xinbo Yang, Lynn M Hassman, Frank Penkava, Lee I Garner, Luke E Springer

JCI Insight· July 2024

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Engineered Self-Regulating Macrophages for Targeted Anti-inflammatory Drug Delivery.
Molly Klimak, Amanda Cimino, Kristin Lenz, Luke Springer, Kelsey Collins

Res Sq· May 2024

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Hydrogel Encapsulation of Genome-Engineered Stem Cells for Long-Term Self-Regulating Anti-Cytokine Therapy.
Kelsey H Collins, Lara Pferdehirt, Leila S Saleh, Alireza Savadipour, Luke E Springer

Gels· February 2023

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Side-chain modification of collagen-targeting peptide prevents dye aggregation for improved molecular imaging of arthritic joints.
Megan S Michie, Baogang Xu, Gail Sudlow, Luke E Springer, Christine T N Pham

J Photochem Photobiol A Chem· February 2022

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Safety Profile of Rapamycin Perfluorocarbon Nanoparticles for Preventing Cisplatin-Induced Kidney Injury.
Qingyu Zhou, Justin Doherty, Antonina Akk, Luke E Springer, Ping Fan

Nanomaterials (Basel)· January 2022

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Non-invasive monitoring of arthritis treatment response via targeting of tyrosine-phosphorylated annexin A2 in chondrocytes.
Shaw-Wei D Tsen, Luke E Springer, Krishna Sharmah Gautam, Rui Tang, Kexian Liang

Arthritis Res Ther· October 2021

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A genome-engineered bioartificial implant for autoregulated anticytokine drug delivery.
Yun-Rak Choi, Kelsey H Collins, Luke E Springer, Lara Pferdehirt, Alison K Ross

Sci Adv· September 2021

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Clinicomolecular Identification of Conserved and Individualized Features of Granulomatous Uveitis.
Lynn M Hassman, Michael A Paley, Ekaterina Esaulova, Grace L Paley, Philip A Ruzycki, Luke Springer

Ophthalmol Sci· March 2021

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Adipose tissue is a critical regulator of osteoarthritis.
Kelsey H Collins, Kristin L Lenz, Eleanor N Pollitt, Daniel Ferguson, Irina Hutson, Luke E Springer

Proc Natl Acad Sci U S A· January 2021

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Complement activation on neutrophils initiates endothelial adhesion and extravasation.
Antonina Akk, Luke E Springer, Lihua Yang, Samantha Hamilton-Burdess, John D Lambris

Mol Immunol· October 2019

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Nanotherapy Targeting NF-κB Attenuates Acute Pain After Joint Injury.
Huimin Yan, Xin Duan, Kelsey H Collins, Luke E Springer, Farshid Guilak

Precis Nanomed· January 2019

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Anti-JNK2 peptide-siRNA nanostructures improve plaque endothelium and reduce thrombotic risk in atherosclerotic mice.
Hua Pan, Rohun U Palekar, Kirk K Hou, John Bacon, Huimin Yan, Luke E Springer

Int J Nanomedicine· October 2018

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Suppression of NF-κB activity via nanoparticle-based siRNA delivery alters early cartilage responses to injury.
Huimin Yan, Xin Duan, Hua Pan, Nilsson Holguin, Muhammad Farooq Rai, Luke E Springer

Proc Natl Acad Sci U S A· October 2016

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Neutrophil Extracellular Traps Enhance Early Inflammatory Response in Sendai Virus-Induced Asthma Phenotype.
Antonina Akk, Luke E Springer, Christine T N Pham

Front Immunol· September 2016

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Neutrophil Proteases Promote Experimental Abdominal Aortic Aneurysm via Extracellular Trap Release and Plasmacytoid Dendritic Cell Activation.
Huimin Yan, Hui-Fang Zhou, Antonina Akk, Ying Hu, Luke E Springer

Arterioscler Thromb Vasc Biol· August 2016

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Peptide-siRNA nanocomplexes targeting NF-κB subunit p65 suppress nascent experimental arthritis.
Hui-fang Zhou, Huimin Yan, Hua Pan, Kirk K Hou, Antonina Akk, Luke E Springer

J Clin Invest· October 2014

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Fumagillin prodrug nanotherapy suppresses macrophage inflammatory response via endothelial nitric oxide.
Hui-fang Zhou, Huimin Yan, Ying Hu, Luke E Springer, Xiaoxia Yang

ACS Nano· July 2014

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Fibrinogen-specific antibody induces abdominal aortic aneurysm in mice through complement lectin pathway activation.
Hui-fang Zhou, Huimin Yan, Paula Bertram, Ying Hu, Luke E Springer

Proc Natl Acad Sci U S A· November 2013

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CD43-mediated IFN-γ production by CD8+ T cells promotes abdominal aortic aneurysm in mice.
Hui-fang Zhou, Huimin Yan, Judy L Cannon, Luke E Springer, Jonathan M Green

J Immunol· May 2013

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