Publications by authors named "Luyu Fan"

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Biased GPCR Signaling: Possible Mechanisms and Therapeutic Applications.
Luyu Fan, Sheng Wang

Biochemistry· March 2025

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Structural basis of psychedelic LSD recognition at dopamine D receptor.
Luyu Fan, Youwen Zhuang, Hongyu Wu, Huiqiong Li, Youwei Xu

Neuron· October 2024

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Flexible scaffold-based cheminformatics approach for polypharmacological drug design.
Zhangcheng Chen, Jing Yu, Huan Wang, Peiyu Xu, Luyu Fan

Cell· April 2024

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Transformation of a Dopamine D Receptor Agonist to Partial Agonists as Novel Antipsychotic Agents.
Ruiquan Liu, Jianzhong Qi, Huan Wang, Luyu Fan, Pei Zhang

J Med Chem· May 2023

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Structure-based design of a novel third-generation antipsychotic drug lead with potential antidepressant properties.
Zhangcheng Chen, Luyu Fan, Huan Wang, Jing Yu, Dengyu Lu

Nat Neurosci· January 2022

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Structure-based discovery of nonhallucinogenic psychedelic analogs.
Dongmei Cao, Jing Yu, Huan Wang, Zhipu Luo, Xinyu Liu, Luyu Fan

Science· January 2022

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Endocannabinoid system in the neurodevelopment of GABAergic interneurons: implications for neurological and psychiatric disorders.
Chang-Geng Song, Xin Kang, Fang Yang, Wan-Qing Du, Jia-Jia Zhang, Lu-Yu Fan, Fang Gao

Rev Neurosci· December 2021

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2-Phenylcyclopropylmethylamine Derivatives as Dopamine D Receptor Partial Agonists: Design, Synthesis, and Biological Evaluation.
Wenzhong Yan, Luyu Fan, Jing Yu, Ruiquan Liu, Huan Wang

J Med Chem· December 2021

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Haloperidol bound D dopamine receptor structure inspired the discovery of subtype selective ligands.
Luyu Fan, Liang Tan, Zhangcheng Chen, Jianzhong Qi, Fen Nie

Nat Commun· February 2020

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