Publications by authors named "Lydia Qian"

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A paREDOX in the control of cholesterol biosynthesis: Does the NADPH sensor and E3 ubiquitin ligase MARCHF6 protect mammalian cells during oxidative stress by controlling sterol biosynthesis?
Nicole M Fenton, Lydia Qian, Eloise G Paine, Laura J Sharpe, Andrew J Brown

Bioessays· July 2024

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SC5D is the sixth enzyme in cholesterol biosynthesis targeted by the E3 ubiquitin ligase MARCHF6.
Nicole M Fenton, Lydia Qian, Nicola A Scott, Eloise G Paine, Laura J Sharpe

Biochim Biophys Acta Mol Cell Biol Lipids· May 2024

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Cholesterol synthesis enzyme SC4MOL is fine-tuned by sterols and targeted for degradation by the E3 ligase MARCHF6.
Lydia Qian, Nicola A Scott, Isabelle M Capell-Hattam, Eliza A Draper, Nicole M Fenton

J Lipid Res· May 2023

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Controlling an E3 ligase and its substrate: A function for MARCHF6 circRNA.
Lydia Qian, Laura J Sharpe, Akira Gokool, Irina Voineagu, Andrew J Brown

Biochim Biophys Acta Mol Cell Biol Lipids· January 2023

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Twin enzymes, divergent control: The cholesterogenic enzymes DHCR14 and LBR are differentially regulated transcriptionally and post-translationally.
Isabelle M Capell-Hattam, Laura J Sharpe, Lydia Qian, Gene Hart-Smith, Anika V Prabhu

J Biol Chem· February 2020

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