Publications by authors named "Lyn Huff"

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The Methyltransferases METTL7A and METTL7B Confer Resistance to Thiol-Based Histone Deacetylase Inhibitors.
Robert W Robey, Christina M Fitzsimmons, Wilfried M Guiblet, William J E Frye, José M González Dalmasy, Lyn M Huff

Mol Cancer Ther· April 2024

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The multidrug resistance transporter P-glycoprotein confers resistance to ferroptosis inducers.
William J E Frye, Lyn M Huff, José M González Dalmasy, Paula Salazar, Rachel M Carter

Cancer Drug Resist· July 2023

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The Multidrug Resistance Transporter P-glycoprotein Confers Resistance to Ferroptosis Inducers.
William J E Frye, Lyn M Huff, José M González Dalmasy, Paula Salazar, Rachel M Carter

bioRxiv· February 2023

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Characterization and tissue localization of zebrafish homologs of the human ABCB1 multidrug transporter.
Robert W Robey, Andrea N Robinson, Fatima Ali-Rahmani, Lyn M Huff, Sabrina Lusvarghi

Sci Rep· December 2021

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Genomic stability at the coding regions of the multidrug transporter gene : insights into the development of alternative drug resistance mechanisms in human leukemia cells.
Kevin G Chen, George E Duran, Mark J Mogul, Yan C Wang, Kevin L Ross, Lyn M Huff

Cancer Drug Resist· November 2020

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Metastatic and recurrent adrenocortical cancer is not defined by its genomic landscape.
Tito Fojo, Lyn Huff, Thomas Litman, Kate Im, Maureen Edgerly

BMC Med Genomics· November 2020

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Leptin Signaling Affects Survival and Chemoresistance of Estrogen Receptor Negative Breast Cancer.
Crystal C Lipsey, Adriana Harbuzariu, Robert W Robey, Lyn M Huff, Michael M Gottesman

Int J Mol Sci· May 2020

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Mycoplasma Infection Mediates Sensitivity of Multidrug-Resistant Cell Lines to Tiopronin: A Cautionary Tale.
Lyn M Huff, Sachi Horibata, Robert W Robey, Matthew D Hall, Michael M Gottesman

J Med Chem· February 2020

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Coexpression of ABCB1 and ABCG2 in a Cell Line Model Reveals Both Independent and Additive Transporter Function.
Andrea N Robinson, Bethelihem G Tebase, Sonia C Francone, Lyn M Huff, Hanna Kozlowski

Drug Metab Dispos· July 2019

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Correction: Screening of cancer tissue arrays identifies CXCR4 on adrenocortical carcinoma: correlates with expression and quantification on metastases using Cu-plerixafor PET.
Ido D Weiss, Lyn M Huff, Moses O Evbuomwan, Xin Xu, Hong Duc Dang

Oncotarget· October 2018

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Screening of cancer tissue arrays identifies CXCR4 on adrenocortical carcinoma: correlates with expression and quantification on metastases using Cu-plerixafor PET.
Ido D Weiss, Lyn M Huff, Moses O Evbuomwan, Xin Xu, Hong Duc Dang

Oncotarget· September 2017

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Microtubule-disrupting chemotherapeutics result in enhanced proteasome-mediated degradation and disappearance of tubulin in neural cells.
Lyn M Huff, Dan L Sackett, Marianne S Poruchynsky, Tito Fojo

Cancer Res· July 2010

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A phase II clinical trial of ixabepilone (Ixempra; BMS-247550; NSC 710428), an epothilone B analog, in patients with metastatic renal cell carcinoma.
Hui Huang, Michael Menefee, Maureen Edgerly, Sen Zhuang, Herb Kotz, Lyn Mickley Huff

Clin Cancer Res· March 2010

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Histone modifications at the ABCG2 promoter following treatment with histone deacetylase inhibitor mirror those in multidrug-resistant cells.
Kenneth K W To, Orsolya Polgar, Lyn M Huff, Kuniaki Morisaki, Susan E Bates

Mol Cancer Res· January 2008

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Relationship of EGFR mutations, expression, amplification, and polymorphisms to epidermal growth factor receptor inhibitors in the NCI60 cell lines.
Wanqing Liu, Xiaolin Wu, Wei Zhang, Raquel C Montenegro, Donna Lee Fackenthal, Lyn Mickley Huff

Clin Cancer Res· November 2007

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Characterization of gene rearrangements leading to activation of MDR-1.
Lyn M Huff, Jong-Seok Lee, Robert W Robey, Tito Fojo

J Biol Chem· December 2006

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Aberrant transcription from an unrelated promoter can result in MDR-1 expression following drug selection in vitro and in relapsed lymphoma samples.
Lyn Mickley Huff, Zheng Wang, Angel Iglesias, Tito Fojo, Jong-Seok Lee

Cancer Res· December 2005

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Genetic and epigenetic modeling of the origins of multidrug-resistant cells in a human sarcoma cell line.
Kevin G Chen, Yan C Wang, Marci E Schaner, Brian Francisco, George E Durán, Lyn M Huff

Cancer Res· October 2005

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Characterization of ABCG2 gene amplification manifesting as extrachromosomal DNA in mitoxantrone-selected SF295 human glioblastoma cells.
V Koneti Rao, Darawalee Wangsa, Robert W Robey, Lyn Huff, Yasumasa Honjo

Cancer Genet Cytogenet· July 2005

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Single-nucleotide polymorphism (SNP) analysis in the ABC half-transporter ABCG2 (MXR/BCRP/ABCP1).
Yasumasa Honjo, Kuniaki Morisaki, Lyn Mickley Huff, Robert W Robey, Jeffrey Hung

Cancer Biol Ther· June 2003

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