Publications by authors named "Lynn Neff"

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Characterization of unique functionalities in c-Src domains required for osteoclast podosome belt formation.
Takuma Matsubara, William N Addison, Shoichiro Kokabu, Lynn Neff, William Horne

J Biol Chem· August 2021

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Cathepsin K-deficient osteocytes prevent lactation-induced bone loss and parathyroid hormone suppression.
Sutada Lotinun, Yoshihito Ishihara, Kenichi Nagano, Riku Kiviranta, Vincent T Carpentier, Lynn Neff

J Clin Invest· May 2019

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The Actin-Binding Protein Cofilin and Its Interaction With Cortactin Are Required for Podosome Patterning in Osteoclasts and Bone Resorption In Vivo and In Vitro.
Detina Zalli, Lynn Neff, Kenichi Nagano, Nah Young Shin, Walter Witke

J Bone Miner Res· September 2016

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The Crosstalk between Osteoclasts and Osteoblasts Is Dependent upon the Composition and Structure of Biphasic Calcium Phosphates.
Yukari Shiwaku, Lynn Neff, Kenichi Nagano, Ken-Ichi Takeyama, Joost de Bruijn

PLoS One· April 2016

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Dynamin and endocytosis are required for the fusion of osteoclasts and myoblasts.
Nah-Young Shin, Hyewon Choi, Lynn Neff, Yumei Wu, Hiroaki Saito

J Cell Biol· October 2014

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Microtubule dynamic instability controls podosome patterning in osteoclasts through EB1, cortactin, and Src.
Martin Biosse Duplan, Detina Zalli, Sebastien Stephens, Serhan Zenger, Lynn Neff

Mol Cell Biol· January 2014

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Osteoclast-specific cathepsin K deletion stimulates S1P-dependent bone formation.
Sutada Lotinun, Riku Kiviranta, Takuma Matsubara, Jorge A Alzate, Lynn Neff

J Clin Invest· February 2013

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SLC4A2-mediated Cl-/HCO3- exchange activity is essential for calpain-dependent regulation of the actin cytoskeleton in osteoclasts.
Fabienne Coury, Serhan Zenger, Andrew K Stewart, Sebastien Stephens, Lynn Neff

Proc Natl Acad Sci U S A· February 2013

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Deletion of Zfp521 rescues the growth plate phenotype in a mouse model of Jansen metaphyseal chondrodysplasia.
Dutmanee Seriwatanachai, Michael J Densmore, Tadatoshi Sato, Diego Correa, Lynn Neff

FASEB J· September 2011

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Zfp521 controls bone mass by HDAC3-dependent attenuation of Runx2 activity.
Eric Hesse, Hiroaki Saito, Riku Kiviranta, Diego Correa, Kei Yamana, Lynn Neff

J Cell Biol· December 2010

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Zfp521 is a target gene and key effector of parathyroid hormone-related peptide signaling in growth plate chondrocytes.
Diego Correa, Eric Hesse, Dutmanee Seriwatanachai, Riku Kiviranta, Hiroaki Saito, Lynn Neff

Dev Cell· October 2010

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c-Cbl and Cbl-b act redundantly to protect osteoclasts from apoptosis and to displace HDAC6 from beta-tubulin, stabilizing microtubules and podosomes.
Enkhtsetseg Purev, Lynn Neff, William C Horne, Roland Baron

Mol Biol Cell· September 2009

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Loss of Cbl-b increases osteoclast bone-resorbing activity and induces osteopenia.
Arata Nakajima, Archana Sanjay, Riccardo Chiusaroli, Naga Suresh Adapala, Lynn Neff

J Bone Miner Res· July 2009

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Dynamin reduces Pyk2 Y402 phosphorylation and SRC binding in osteoclasts.
Angela Bruzzaniti, Lynn Neff, Amanda Sandoval, Liping Du, William C Horne

Mol Cell Biol· July 2009

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Zfp521 antagonizes Runx2, delays osteoblast differentiation in vitro, and promotes bone formation in vivo.
Meilin Wu, Eric Hesse, Frederic Morvan, Jian-Ping Zhang, Diego Correa, Lynn Neff

Bone· April 2009

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Increased energy expenditure and insulin sensitivity in the high bone mass DeltaFosB transgenic mice.
Glenn C Rowe, Cheol Soo Choi, Lynn Neff, William C Horne, Gerald I Shulman

Endocrinology· January 2009

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Doubly truncated FosB isoform (Delta2DeltaFosB) induces osteosclerosis in transgenic mice and modulates expression and phosphorylation of Smads in osteoblasts independent of intrinsic AP-1 activity.
George Sabatakos, Glenn C Rowe, Marie Kveiborg, Meilin Wu, Lynn Neff

J Bone Miner Res· May 2008

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Defective microtubule-dependent podosome organization in osteoclasts leads to increased bone density in Pyk2(-/-) mice.
Hava Gil-Henn, Olivier Destaing, Natalie A Sims, Kazuhiro Aoki, Neil Alles, Lynn Neff

J Cell Biol· September 2007

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Calpain is required for normal osteoclast function and is down-regulated by calcitonin.
Marilena Marzia, Riccardo Chiusaroli, Lynn Neff, Na-Young Kim, Athar H Chishti

J Biol Chem· April 2006

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Dynamin forms a Src kinase-sensitive complex with Cbl and regulates podosomes and osteoclast activity.
Angela Bruzzaniti, Lynn Neff, Archana Sanjay, William C Horne, Pietro De Camilli

Mol Biol Cell· July 2005

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Src kinase activity is essential for osteoclast function.
Tsuyoshi Miyazaki, Archana Sanjay, Lynn Neff, Sakae Tanaka, William C Horne

J Biol Chem· April 2004

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Regulation of cytochrome c oxidase activity by c-Src in osteoclasts.
Tsuyoshi Miyazaki, Lynn Neff, Sakae Tanaka, William C Horne, Roland Baron

J Cell Biol· March 2003

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