Publications by authors named "MJ Dyer"

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The BH3-only protein NOXA is essential for apoptosis induction by BH3-mimetics targeting BCL2 or BCL-X in DLBCL.
Nahide Yildirim, Marius Anders, Victoria M Smith, Sandrine Jayne, Moritz Assmann, Martin J S Dyer

Br J Haematol· October 2025

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The unfolded protein response influences therapy outcome and disease progression in chronic lymphocytic leukaemia.
Umair Tahir Khan, Kim Clarke, Gina Eagle, Melanie Oates, Peter Hillmen, Martin J S Dyer

Sci Rep· July 2025

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In vitro comparison of CD20xCD3 bispecific antibodies against diffuse large B-cell lymphoma (DLBCL) cell lines with different levels of expression of CD20.
Joshua S Bray, Gethin R Thomas, Victoria M Smith, Adam Wright, Sandrine Jayne, Martin J S Dyer

Br J Haematol· May 2025

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Long-term outcomes of chemoimmunotherapy with obinutuzumab/chlorambucil in chronic lymphocytic leukemia.
Valentin Goede, Kirsten Fischer, Sandra Robrecht, Adam Giza, Martin J S Dyer

Blood Adv· May 2025

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The BCL2 family: from apoptosis mechanisms to new advances in targeted therapy.
Meike Vogler, Yannick Braun, Victoria M Smith, Mike-Andrew Westhoff, Raquel S Pereira, Martin Js Dyer

Signal Transduct Target Ther· March 2025

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The chromosomal translocation t(1;6)(p35.3;p25.2), recurrent in chronic lymphocytic leukaemia, leads to RCC1::IRF4 fusion.
Sandrine Jayne, Cristina López, Natalie Put, Inga Nagel, Els Lierman, Martin J S Dyer

Br J Haematol· December 2024

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Impact of the clinically approved BTK inhibitors on the conformation of full-length BTK and analysis of the development of BTK resistance mutations in chronic lymphocytic leukemia.
Raji E Joseph, Thomas E Wales, Sandrine Jayne, Robert G Britton, D Bruce Fulton, Martin J S Dyer

Elife· December 2024

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Impact of the clinically approved BTK inhibitors on the conformation of full-length BTK and analysis of the development of BTK resistance mutations in chronic lymphocytic leukemia.
Raji E Joseph, Thomas E Wales, Sandrine Jayne, Robert G Britton, D Bruce Fulton, Martin J S Dyer

bioRxiv· October 2024

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Monitoring of molecular responses to tirabrutinib in a cohort of exceptional responders with relapsed/refractory mantle cell lymphoma.
Abdullah N M Alqahtani, Sandrine Jayne, Matthew J Ahearne, Christopher S Trethewey, Sai S Duraisingham, Martin J S Dyer

EJHaem· August 2024

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BCL2 inhibition: back to the future!
Martin J S Dyer, Harriet S Walter

Blood· May 2024

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Identification of a novel form of caspase-independent cell death triggered by BH3-mimetics in diffuse large B-cell lymphoma cell lines.
Nahide Yildirim, Lakshmi Sarojam, Victoria M Smith, Nadja M Pieper, Marius Anders, Martin J S Dyer

Cell Death Dis· April 2024

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Heavy-element production in a compact object merger observed by JWST.
Andrew J Levan, Benjamin P Gompertz, Om Sharan Salafia, Mattia Bulla, Eric Burns, Martin J Dyer

Nature· February 2024

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A rotating white dwarf shows different compositions on its opposite faces.
Ilaria Caiazzo, Kevin B Burdge, Pier-Emmanuel Tremblay, James Fuller, Lilia Ferrario, Martin J Dyer

Nature· August 2023

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Highly variable hearing loss due to POU4F3 (c.37del) is revealed by longitudinal, frequency specific analyses.
Sushma Singh, Cindy Penney, Anne Griffin, Geoffrey Woodland, Salem Werdyani, Matthew J Dyer

Eur J Hum Genet· July 2023

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BTK mutations in patients with chronic lymphocytic leukemia receiving tirabrutinib.
Ross A Jackson, Robert G Britton, Sandrine Jayne, Susann Lehmann, Caroline M Cowley, Martin J S Dyer

Blood Adv· July 2023

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Obinutuzumab Versus Rituximab Immunochemotherapy in Previously Untreated iNHL: Final Results From the GALLIUM Study.
William Townsend, Wolfgang Hiddemann, Christian Buske, Guillaume Cartron, David Cunningham, Martin J S Dyer

Hemasphere· July 2023

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Computational modeling of DLBCL predicts response to BH3-mimetics.
Ielyaas Cloete, Victoria M Smith, Ross A Jackson, Andrea Pepper, Chris Pepper, Martin J S Dyer

NPJ Syst Biol Appl· June 2023

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Venetoclax retreatment of patients with chronic lymphocytic leukemia after a previous venetoclax-based regimen.
Meghan C Thompson, Rosemary A Harrup, Catherine C Coombs, Lindsey E Roeker, Jeffrey J Pu, Martin J S Dyer

Blood Adv· August 2022

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Successful Retreatment With Venetoclax in a Patient With Chronic Lymphocytic Leukemia.
Ross A Jackson, Victoria M Smith, Sandrine Jayne, Cosima Drewes, Susanne Bens, Martin J S Dyer

Hemasphere· August 2022

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Chronic lymphocytic leukaemia therapy: is less more?
Harriet S Walter, Martin J S Dyer

Lancet Haematol· March 2022

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Limitations of Monitoring Disease Progression Using Circulating Tumor DNA in Lymphoma: An Example From Primary Cutaneous DLBCL Leg-type.
Christopher S Trethewey, Harriet S Walter, Abdullah N M Alqahtani, Ralf Schmid, David S Guttery, Martin J S Dyer

Hemasphere· March 2022

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Pooled analysis of safety data from clinical trials evaluating acalabrutinib monotherapy in mature B-cell malignancies.
Richard R Furman, John C Byrd, Roger G Owen, Susan M O'Brien, Jennifer R Brown, Martin J S Dyer

Leukemia· November 2021

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Acalabrutinib for treatment of diffuse large B-cell lymphoma: results from a phase Ib study.
Paolo Strati, Sven De Vos, Jia Ruan, Kami J Maddocks, Christopher R Flowers, Martin J S Dyer

Haematologica· October 2021

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Therapy-related leukaemias with balanced translocations can arise from pre-existing clonal haematopoiesis.
Richard Dillon, Matthew J Ahearne, Lynn Quek, Nicola Potter, Jelena Jovanovic, Martin J S Dyer

Leukemia· August 2021

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A Phase 1b Study to Evaluate the Safety and Efficacy of Durvalumab in Combination With Tremelimumab or Danvatirsen in Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma.
Vincent Ribrag, Seung Tae Lee, David Rizzieri, Martin J S Dyer, Luis Fayad

Clin Lymphoma Myeloma Leuk· May 2021

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