Publications by authors named "Magda Opsomer"

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The IL-6 hypothesis in COVID-19: A phase 2, randomised, double-blind, placebo-controlled study to evaluate the efficacy and safety of free IL-6 sequestration by the monoclonal antibody sirukumab in severe and critical COVID-19.
Robert L Gottlieb, Meredith Clement, Paul Cook, Audra Deveikis, Kap Sum Foong, Magda Opsomer

J Infect· October 2024

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Etravirine in treatment-experienced HIV-1-infected children 1 year to less than 6 years of age.
Christine E MacBrayne, Richard M Rutstein, Andrew A Wiznia, Bobbie Graham, Carmelita G Alvero, Magda Opsomer

AIDS· July 2021

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The DIANA Study: Continued Access to Darunavir/Ritonavir (DRV/r) and Long-Term Safety Follow-Up in HIV-1-Infected Pediatric Patients Aged 3 to < 18 Years.
Avy Violari, Maysseb Masenya, Stephane Blanche, Simon Vanveggel, Veerle Hufkens, Magda Opsomer

Drug Saf· April 2021

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Week 96 results of a phase 3 trial of darunavir/cobicistat/emtricitabine/tenofovir alafenamide in treatment-naive HIV-1 patients.
Chloe Orkin, Joseph J Eron, Jürgen Rockstroh, Daniel Podzamczer, Stefan Esser, Magda Opsomer

AIDS· April 2020

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Week 48 Resistance Analyses of the Once-Daily, Single-Tablet Regimen Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (D/C/F/TAF) in Adults Living with HIV-1 from the Phase III Randomized AMBER and EMERALD Trials.
Erkki Lathouwers, Eric Y Wong, Kimberley Brown, Bryan Baugh, Anne Ghys, Magda Opsomer

AIDS Res Hum Retroviruses· January 2020

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Week 96 efficacy and safety results of the phase 3, randomized EMERALD trial to evaluate switching from boosted-protease inhibitors plus emtricitabine/tenofovir disoproxil fumarate regimens to the once daily, single-tablet regimen of darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) in treatment-experienced, virologically-suppressed adults living with HIV-1.
Joseph J Eron, Chloe Orkin, Douglas Cunningham, Federico Pulido, Frank A Post, Magda Opsomer

Antiviral Res· October 2019

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Bioequivalence of the Once-Daily Single-Tablet Regimen of Darunavir, Cobicistat, Emtricitabine, and Tenofovir Alafenamide Compared to Combined Intake of the Separate Agents and the Effect of Food on Bioavailability.
Herta M Crauwels, Bryan Baugh, Erika Van Landuyt, Simon Vanveggel, Anja Hijzen, Magda Opsomer

Clin Pharmacol Drug Dev· May 2019

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Evaluation of Cardiovascular Disease Risk in HIV-1-Infected Patients Treated with Darunavir.
Magda Opsomer, Dessislava Dimitrova, Johan Verspeelt, Amy Purrington, Abdul Mehbob

Drugs R D· September 2018

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Correction to: Evaluation of Cardiovascular Disease Risk in HIV‑1-Infected Patients Treated with Darunavir.
Magda Opsomer, Dessislava Dimitrova, Johan Verspeelt, Amy Purrington, Abdul Mehbob

Drugs R D· September 2018

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A week-48 randomized phase-3 trial of darunavir/cobicistat/emtricitabine/tenofovir alafenamide in treatment-naive HIV-1 patients.
Joseph J Eron, Chloe Orkin, Joel Gallant, Jean-Michel Molina, Eugenia Negredo, Magda Opsomer

AIDS· July 2018

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Assessment of etravirine resistance in HIV-1-infected paediatric patients using population and deep sequencing: final results of the PIANO study.
Lotke Tambuyzer, Kim Thys, Annemie Hoogstoel, Steven Nijs, Frank Tomaka, Magda Opsomer

Antivir Ther· January 2018

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Efficacy and safety of switching from boosted protease inhibitors plus emtricitabine and tenofovir disoproxil fumarate regimens to single-tablet darunavir, cobicistat, emtricitabine, and tenofovir alafenamide at 48 weeks in adults with virologically suppressed HIV-1 (EMERALD): a phase 3, randomised, non-inferiority trial.
Chloe Orkin, Jean-Michel Molina, Eugenia Negredo, José R Arribas, Joseph Gathe, Magda Opsomer

Lancet HIV· January 2018

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Etravirine combined with antiretrovirals other than darunavir/ritonavir for HIV-1-infected, treatment-experienced adults: Week 48 results of a phase IV trial.
Eduardo Arathoon, Asad Bhorat, Rodica Silaghi, Herta Crauwels, Ludo Lavreys, Magda Opsomer

SAGE Open Med· January 2017

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Pharmacokinetics and Pharmacokinetic/Pharmacodynamic Relationships of Etravirine in HIV-1-Infected, Treatment-Experienced Children and Adolescents in PIANO.
Thomas N Kakuda, Anne Brochot, Bruce Green, Steven Nijs, Peter Vis, Magda Opsomer

J Clin Pharmacol· November 2016

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Phase IIIb, open-label single-arm trial of darunavir/cobicistat (DRV/COBI): Week 48 subgroup analysis of HIV-1-infected treatment-nave adults.
Karen Tashima, Gordon Crofoot, Frank L Tomaka, Thomas N Kakuda, Anne Brochot, Magda Opsomer

J Int AIDS Soc· January 2016

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Week 48 results of a Phase IV trial of etravirine with antiretrovirals other than darunavir/ritonavir in HIV-1-infected treatment-experienced adults.
Eduardo Arathoon, Asad Bhorat, Rodica Silaghi, Herta Crauwels, Ludo Lavreys, Magda Opsomer

J Int AIDS Soc· January 2016

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Bioequivalence of a darunavir/cobicistat fixed-dose combination tablet versus single agents and food effect in healthy volunteers.
Thomas N Kakuda, Tom Van De Casteele, Romana Petrovic, Mark Neujens, Hiba Salih, Magda Opsomer

Antivir Ther· August 2015

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Darunavir/cobicistat once daily for the treatment of HIV.
Thomas N Kakuda, Herta Crauwels, Magda Opsomer, Frank Tomaka, Tom van de Casteele

Expert Rev Anti Infect Ther· June 2015

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Safety and efficacy of darunavir/ritonavir in treatment-experienced pediatric patients: week 48 results of the ARIEL trial.
Avy Violari, Rosa Bologna, Nagalingeswaran Kumarasamy, Jose Henrique Pilotto, Annemie Hendrickx, Magda Opsomer

Pediatr Infect Dis J· May 2015

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Cobicistat-boosted darunavir in HIV-1-infected adults: week 48 results of a Phase IIIb, open-label single-arm trial.
Karen Tashima, Gordon Crofoot, Frank L Tomaka, Thomas N Kakuda, Anne Brochot, Magda Opsomer

AIDS Res Ther· April 2015

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Efficacy and safety of darunavir/ritonavir at 48 weeks in treatment-naïve, HIV-1-infected adolescents: results from a phase 2 open-label trial (DIONE).
Patricia Flynn, Svitlana Komar, Stephane Blanche, Carlo Giaquinto, Antoni Noguera-Julian, Magda Opsomer

Pediatr Infect Dis J· September 2014

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Pharmacokinetics of darunavir in fixed-dose combination with cobicistat compared with coadministration of darunavir and ritonavir as single agents in healthy volunteers.
Thomas N Kakuda, Magda Opsomer, Maarten Timmers, Koen Iterbeke, Tom Van De Casteele

J Clin Pharmacol· August 2014

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