Publications by authors named "Magnus Doverskog"

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Golexanolone affords sustained improvement of Parkinson's symptoms in rats by reducing microglia activation that restores the glutamate-GABA-dopamine pathway.
Maria A Pedrosa, Gergana Mincheva, Mar Martinez-Garcia, Lola Vazquez, Thomas P Blackburn, Magnus Doverskog

Neuropharmacology· February 2026

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Golexanolone Attenuates Neuroinflammation, Fatigue, and Cognitive and Motor Impairment in Diverse Neuroinflammatory Disorders.
Marta Llansola, Gergana Mincheva, Yaiza M Arenas, Paula Izquierdo-Altarejos, Maria A Pedrosa, Magnus Doverskog

Pharmaceuticals (Basel)· November 2025

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Golexanolone affords sustained microglia and astrocytes activation improvement in a rat model of Parkinson's disease.
Gergana Mincheva, Maria A Pedrosa, Mar Martínez-García Vázquez, Lola Vazquez, Thomas P Blackburn, Magnus Doverskog

Front Immunol· September 2025

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Allopregnanolone and its antagonist modulate neuroinflammation and neurological impairment.
Torbjörn Bäckström, Magnus Doverskog, Thomas P Blackburn, Bruce F Scharschmidt, Vicente Felipo

Neurosci Biobehav Rev· June 2024

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Golexanolone reduces glial activation in the striatum and improves non-motor and some motor alterations in a rat model of Parkinson's disease.
Paula Izquierdo-Altarejos, Yaiza M Arenas, Mar Martínez-García, Lola Vázquez, Gergana Mincheva, Magnus Doverskog

Front Aging Neurosci· June 2024

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Neuroinflammation alters GABAergic neurotransmission in hyperammonemia and hepatic encephalopathy, leading to motor incoordination. Mechanisms and therapeutic implications.
Marta Llansola, Yaiza M Arenas, María Sancho-Alonso, Gergana Mincheva, Andrea Palomares-Rodriguez, Magnus Doverskog

Front Pharmacol· March 2024

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Golexanolone improves fatigue, motor incoordination and gait and memory in rats with bile duct ligation.
Yaiza M Arenas, Paula Izquierdo-Altarejos, Mar Martinez-García, Carla Giménez-Garzó, Gergana Mincheva, Magnus Doverskog

Liver Int· February 2024

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Extra-Synaptic GABA Receptor Potentiation and Neurosteroid-Induced Learning Deficits Are Inhibited by GR3027, a GABA Modulating Steroid Antagonist.
Sara K S Bengtsson, Jessica Sjöstedt, Evgenya Malinina, Roshni Das, Magnus Doverskog

Biomolecules· October 2023

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The GABA system, a new target for medications against cognitive impairment-Associated with neuroactive steroids.
Torbjörn Bäckström, Sahruh Turkmen, Roshni Das, Magnus Doverskog, Thomas P Blackburn

J Intern Med· September 2023

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Neurosteroid Activation of GABA-A Receptors: A Potential Treatment Target for Symptoms in Primary Biliary Cholangitis?
Aaron Wetten, Laura Ogle, George Mells, Vinod S Hegade, Laura Jopson, Magnus Doverskog

Can J Gastroenterol Hepatol· December 2022

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Golexanolone, a GABA receptor modulating steroid antagonist, restores motor coordination and cognitive function in hyperammonemic rats by dual effects on peripheral inflammation and neuroinflammation.
Gergana Mincheva, Carla Gimenez-Garzo, Paula Izquierdo-Altarejos, Mar Martinez-Garcia, Magnus Doverskog

CNS Neurosci Ther· November 2022

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A pilot study of golexanolone, a new GABA-A receptor-modulating steroid antagonist, in patients with covert hepatic encephalopathy.
Sara Montagnese, Mette Lauridsen, Hendrik Vilstrup, Lisa Zarantonello, Géza Lakner, Magnus Doverskog

J Hepatol· July 2021

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GR3027 reversal of neurosteroid-induced, GABA-A receptor-mediated inhibition of human brain function: an allopregnanolone challenge study.
Maja Johansson, Maria Månsson, Lars-Eric Lins, Bruce Scharschmidt, Magnus Doverskog

Psychopharmacology (Berl)· May 2018

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Acceleration of Amyloidosis by Inflammation in the Amyloid-Beta Marmoset Monkey Model of Alzheimer's Disease.
Ingrid H Philippens, Paul R Ormel, Guus Baarends, Maja Johansson, Ed J Remarque, Magnus Doverskog

J Alzheimers Dis· February 2018

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GABAA receptor modulating steroid antagonists (GAMSA) are functional in vivo.
Maja Johansson, Jessica Strömberg, Gianna Ragagnin, Magnus Doverskog, Torbjörn Bäckström

J Steroid Biochem Mol Biol· June 2016

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GR3027 antagonizes GABAA receptor-potentiating neurosteroids and restores spatial learning and motor coordination in rats with chronic hyperammonemia and hepatic encephalopathy.
Maja Johansson, Ana Agusti, Marta Llansola, Carmina Montoliu, Jessica Strömberg, Magnus Doverskog

Am J Physiol Gastrointest Liver Physiol· September 2015

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Baculovirus-mediated gene transfer and recombinant protein expression do not interfere with insulin dependent phosphorylation of PKB/Akt in human SHSY-5Y and C3A cells.
Monica Andersson, Malin Warolén, Joakim Nilsson, Martin Selander, Catharina Sterky, Magnus Doverskog

BMC Cell Biol· February 2007

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Production of a truncated soluble human semicarbazide-sensitive amine oxidase mediated by a GST-fusion protein secreted from HEK293 cells.
Johan Ohman, Emma Jakobsson, Ulla Källström, Annette Elmblad, Akbar Ansari, Magnus Doverskog

Protein Expr Purif· April 2006

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Membrane protein isolation by in situ solubilization, partitioning and affinity adsorption in aqueous two-phase systems. Purification of the human type 1 11beta-hydroxysteroid dehydrogenase.
Margrit Roobol-Bóza, Viveka Dolby, Magnus Doverskog, Asa Barrefelt, Fredrik Lindqvist

J Chromatogr A· July 2004

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Effect of glycine on the cell yield and growth rate of Escherichia coli: evidence for cell-density-dependent glycine degradation as determined by (13)C NMR spectroscopy.
Ling Han, Magnus Doverskog, Sven-Olof Enfors, Lena Häggström

J Biotechnol· January 2002

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