Publications by authors named "Maiko Iida"

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Discovery of 2-(6-{[(1R,2R)-2-hydroxycyclohexyl]amino}-4,5-dimethylpyridazin-3-yl)-5-(trifluoromethyl)phenol (ASP0965): A potent, orally active and brain-penetrable NLRP3 inflammasome inhibitor with a novel scaffold for the treatment of α-synucleinopathy.
Yusuke Inagaki, Takashi Kamikubo, Ikumi Kuriwaki, Junko Watanabe, Susumu Yamaki, Maiko Iida

Bioorg Med Chem· February 2025

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Structure-activity relationship studies of ME1111, a novel antifungal agent for topical treatment of onychomycosis.
Naomi Takei-Masuda, Maiko Iida, Makoto Ohyama, Kaori Kaneda, Kenji Ueda

J Antibiot (Tokyo)· January 2025

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Fusion of breast cancer MCF-7 cells with mesenchymal stem cells rearranges interallelic gene expression and enhances cancer malignancy.
Shuuji Mawaribuchi, Maiko Iida, Yoshikazu Haramoto

Biochem Biophys Res Commun· December 2024

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Liquid chromatography-mass spectrometry analyses of polyprenyl phosphates in Escherichia coli cells in which genes for isoprenoid synthesis are amplified.
Yoshimitsu Murata, Tomotaka Jitsukawa, Maiko Iida, Toshiaki Furuta, Yoshikazu Haramoto

J Biosci Bioeng· May 2023

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Suppression of phenotype of Escherichia coli mutant defective in farnesyl diphosphate synthase by overexpression of gene for octaprenyl diphosphate synthase.
Hiroshi Takahashi, Yuta Aihara, Yukihiro Ogawa, Yoshimitsu Murata, Ken-Ichi Nakajima, Maiko Iida

Biosci Biotechnol Biochem· June 2018

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The Open Form Inducer Approach for Structure-Based Drug Design.
Daniel Ken Inaoka, Maiko Iida, Toshiyuki Tabuchi, Teruki Honma, Nayoung Lee

PLoS One· July 2017

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Design and synthesis of potent substrate-based inhibitors of the Trypanosoma cruzi dihydroorotate dehydrogenase.
Daniel Ken Inaoka, Maiko Iida, Satoshi Hashimoto, Toshiyuki Tabuchi, Takefumi Kuranaga

Bioorg Med Chem· February 2017

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Characterization of Antifungal Activity and Nail Penetration of ME1111, a New Antifungal Agent for Topical Treatment of Onychomycosis.
Yuji Tabata, Naomi Takei-Masuda, Natsuki Kubota, Sho Takahata, Makoto Ohyama, Maiko Iida

Antimicrob Agents Chemother· February 2016

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Functional analysis of synthetic substructures of polytheonamide B: a transmembrane channel-forming peptide.
Shigeru Matsuoka, Naoki Shinohara, Tomoaki Takahashi, Maiko Iida, Masayuki Inoue

Angew Chem Int Ed Engl· May 2011

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Total synthesis of the large non-ribosomal peptide polytheonamide B.
Masayuki Inoue, Naoki Shinohara, Shintaro Tanabe, Tomoaki Takahashi, Ken Okura, Maiko Iida

Nat Chem· April 2010

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Crystal structure of enoyl-acyl carrier protein reductase (FabK) from Streptococcus pneumoniae reveals the binding mode of an inhibitor.
Jun Saito, Mototsugu Yamada, Takashi Watanabe, Maiko Iida, Hideo Kitagawa

Protein Sci· April 2008

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Phenylimidazole derivatives as specific inhibitors of bacterial enoyl-acyl carrier protein reductase FabK.
Tomohiro Ozawa, Hideo Kitagawa, Yasuo Yamamoto, Sho Takahata, Maiko Iida

Bioorg Med Chem· December 2007

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Phenylimidazole derivatives as new inhibitors of bacterial enoyl-ACP reductase FabK.
Hideo Kitagawa, Tomohiro Ozawa, Sho Takahata, Maiko Iida

Bioorg Med Chem Lett· September 2007

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Phenylimidazole derivatives of 4-pyridone as dual inhibitors of bacterial enoyl-acyl carrier protein reductases FabI and FabK.
Hideo Kitagawa, Tomohiro Ozawa, Sho Takahata, Maiko Iida, Jun Saito

J Med Chem· September 2007

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Discovery of 4-Pyridone derivatives as specific inhibitors of enoyl-acyl carrier protein reductase (FabI) with antibacterial activity against Staphylococcus aureus.
Sho Takahata, Maiko Iida, Takuji Yoshida, Ko Kumura, Hideo Kitagawa

J Antibiot (Tokyo)· February 2007

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4-Pyridone derivatives as new inhibitors of bacterial enoyl-ACP reductase FabI.
Hideo Kitagawa, Ko Kumura, Sho Takahata, Maiko Iida, Kunio Atsumi

Bioorg Med Chem· January 2007

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AG205, a novel agent directed against FabK of Streptococcus pneumoniae.
Sho Takahata, Maiko Iida, Yumi Osaki, Jun Saito, Hideo Kitagawa

Antimicrob Agents Chemother· August 2006

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Role of fosfomycin in a synergistic combination with ofloxacin against Pseudomonas aeruginosa growing in a biofilm.
Koichi Monden, Eiichi Ando, Maiko Iida, Hiromi Kumon

J Infect Chemother· September 2002

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