Publications by authors named "Malcolm Dunlop"

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Global trends in incidence, death, burden and risk factors of early-onset cancer from 1990 to 2019.
Jianhui Zhao, Liying Xu, Jing Sun, Mingyang Song, Lijuan Wang, Shuai Yuan, Yingshuang Zhu, Zhengwei Wan, Susanna Larsson, Konstantinos Tsilidis

BMJ Oncol· September 2023

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Promises under pressure: the modest predictive power of polygenic risk scores.
Rachel Horton, Malcolm Dunlop, Margaret McCartney, Amit Sud, Richard Sullivan

Eur J Hum Genet· January 2026

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Accelerated biological aging and its hallmarks in DNA methylation drive the association between unhealthy lifestyles and the onset of colorectal cancer.
Jing Sun, Min Liu, Xiaoqian Zhang, Xinxuan Li, Jingyu Ye, Malcolm G Dunlop

EBioMedicine· December 2025

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Genome-wide gene-environment interaction study uncovers 162 vitamin D status variants using a precise ambient UVB measure.
Rasha Shraim, Maria Timofeeva, Cathy Wyse, Jos van Geffen, Michiel van Weele, Malcolm G Dunlop

Nat Commun· November 2025

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Association between methylation quantitative trait loci and colorectal cancer risk, survival and cancer recurrence.
Ines Mesa-Eguiagaray, Andrii Iakovliev, Xue Li, Maria Timofeeva, Yazhou He, Malcolm G Dunlop

Br J Cancer· September 2025

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Risk factors and clinical consequences of interval cancers arising within faecal immunochemical testing-based colorectal cancer screening programme.
Adam D Gerrard, Roberta Garau, Yasuko Maeda, Alastair Thomson, Evropi Theodoratou, Malcolm G Dunlop

BJS Open· September 2025

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Clinical impact of double-faecal immunochemical testing following implementation into standard triage and investigation of primary care referrals in patients with lower gastrointestinal symptoms.
Adam D Gerrard, Yasuko Maeda, Colin Noble, Frances Gunn, Lorna Porteous, Malcolm G Dunlop

BJS Open· September 2025

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Single and double faecal immunochemical test strategies are effective in risk stratification for patients with symptoms of per rectal bleeding suggestive of colorectal cancer.
Fatima Shah, Frances Gunn, Malcolm G Dunlop, , Farhat V N Din

BJS Open· September 2025

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Loss of colonic fidelity enables multilineage plasticity and metastasis.
Patrizia Cammareri, Michela Raponi, Yourae Hong, Caroline V Billard, Nat Peckett, Malcolm G Dunlop

Nature· August 2025

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A genome-wide association study in 10,000 individuals links plasma N-glycome to liver disease and anti-inflammatory proteins.
Sodbo Sharapov, Anna Timoshchuk, Olga Zaytseva, Denis E Maslov, Anna Soplenkova, Malcolm Dunlop

Nat Commun· July 2025

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The Increased Early Onset Colorectal Cancer in South East Scotland Is Indicative of a Wider UK Problem.
Adam D Gerrard, Hannah Garside, Yasuko Maeda, Evropi Theodoratou, Malcolm G Dunlop

Cancers (Basel)· June 2025

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Decoding the genetic and environmental forces in propelling the surge of early-onset colorectal cancer.
Jianhui Zhao, Haosen Ji, Kangning Li, Guirong Yu, Siyun Zhou, Malcolm Dunlop

Chin Med J (Engl)· May 2025

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Author Correction: Deep learning and genome-wide association meta-analyses of bone marrow adiposity in the UK Biobank.
Wei Xu, Ines Mesa-Eguiagaray, David M Morris, Chengjia Wang, Calum D Gray, Malcolm G Dunlop

Nat Commun· May 2025

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Author Correction: Trans-ancestry transcriptome-wide association and functional studies to uncover novel susceptibility genes and therapeutic targets for colorectal cancer.
Lijuan Wang, Lidan Hu, Jing Sun, Jianhui Zhao, Siyun Zhou, Malcolm Dunlop

NPJ Precis Oncol· May 2025

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Genetic variation at 11q23.1 confers colorectal cancer risk by dysregulation of colonic tuft cell transcriptional activator .
Vidya Rajasekaran, Bradley T Harris, Ruby T Osborn, Claire Smillie, Kevin Donnelly, Malcolm G Dunlop

Gut· April 2025

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Trans-ancestry transcriptome-wide association and functional studies to uncover novel susceptibility genes and therapeutic targets for colorectal cancer.
Lijuan Wang, Lidan Hu, Jing Sun, Jianhui Zhao, Siyun Zhou, Malcolm Dunlop

NPJ Precis Oncol· April 2025

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Integration of multi-omics data to unveil the molecular landscape and role of piRNAs in early-onset colorectal cancer.
Siyun Zhou, Lili Yu, Jianhui Zhao, Qian Xiao, Jing Sun, Malcolm G Dunlop

BMC Med· April 2025

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Deep learning and genome-wide association meta-analyses of bone marrow adiposity in the UK Biobank.
Wei Xu, Ines Mesa-Eguiagaray, David M Morris, Chengjia Wang, Calum D Gray, Malcolm G Dunlop

Nat Commun· January 2025

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Exposure to air pollution increases susceptibility to ulcerative colitis through epigenetic alterations in CXCR2 and MHC class III region.
Jie Chen, Han Zhang, Tian Fu, Jianhui Zhao, Jan Krzysztof Nowak, Malcolm G Dunlop

EBioMedicine· December 2024

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Systematic prioritization of functional variants and effector genes underlying colorectal cancer risk.
Philip J Law, James Studd, James Smith, Jayaram Vijayakrishnan, Bradley T Harris, Malcolm G Dunlop

Nat Genet· October 2024

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Diagnostic Performance of Faecal Immunochemical Testing (FIT) in Patients with Lynch Syndrome Scheduled for Colonoscopic Surveillance.
Adam D Gerrard, Yasuko Maeda, Judith Strachan, Doug Speake, Malcolm G Dunlop

Diagnostics (Basel)· October 2024

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Repeat Faecal Immunochemical Testing for Colorectal Cancer Detection in Symptomatic and Screening Patients: A Systematic Review and Meta-Analysis.
Adam D Gerrard, Roberta Garau, Wei Xu, Yasuko Maeda, Malcolm G Dunlop

Cancers (Basel)· September 2024

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Colorectal cancer prevalence in faecal immunochemical test non-returners: potential for health inequality in symptomatic referral pathways.
Adam D Gerrard, Jonty Coxon, Yasuko Maeda, Evropi Theodoratou, Malcolm G Dunlop

BJS Open· September 2024

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Systematic investigation of genetically determined plasma and urinary metabolites to discover potential interventional targets for colorectal cancer.
Jing Sun, Jianhui Zhao, Siyun Zhou, Xinxuan Li, Tengfei Li, Malcolm G Dunlop

J Natl Cancer Inst· August 2024

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Impact of ambient air pollution on colorectal cancer risk and survival: insights from a prospective cohort and epigenetic Mendelian randomization study.
Fangyuan Jiang, Jianhui Zhao, Jing Sun, Wenxi Chen, Yuyuan Zhao, Malcolm G Dunlop

EBioMedicine· May 2024

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Fine-mapping analysis including over 254,000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes.
Zhishan Chen, Xingyi Guo, Ran Tao, Jeroen R Huyghe, Philip J Law, Malcolm G Dunlop

Nat Commun· April 2024

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