Publications by authors named "Malcolm Martin"

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Design and characterization of HIV-1 vaccine candidates to elicit antibodies targeting multiple epitopes.
Harry B Gristick, Harald Hartweger, Yoshiaki Nishimura, Edem Gavor, Kaito Nagashima, Malcolm A Martin

J Exp Med· October 2025

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Consistent Induction of Broadly Neutralizing HIV Antibodies by a Novel Two-Step Mechanism Informs Immunogen Design.
Ashwin N Skelly, Harry B Gristick, Hui Li, Edem Gavor, Andrew J Connell, Malcolm A Martin

bioRxiv· October 2025

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Clonal expansion and diversification of germinal center and memory B cell responses to booster immunization in primates.
Lachlan P Deimel, Yoshiaki Nishimura, Gabriela S Silva Santos, Viren A Baharani, Brianna Hernandez, Malcolm A Martin

Cell Rep· August 2025

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Design and characterization of HIV-1 vaccine candidates to elicit antibodies targeting multiple epitopes.
Harry B Gristick, Harald Hartweger, Yoshiaki Nishimura, Edem Gavor, Kaito Nagashima, Malcolm A Martin

bioRxiv· July 2025

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Impact of Delayed Early Antiretroviral Therapy Initiation on Treatment Outcomes in Infant Macaques Exposed to SHIVAD8.
Li Ma, Yoshiaki Nishimura, Xueling Wu, Olivia Donau, Eunice Vincent, Malcolm Martin

Viruses· June 2025

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Clonal Expansion and Diversification of Germinal Center and Memory B Cell Responses to Booster Immunization in Primates.
Lachlan P Deimel, Yoshiaki Nishimura, Gabriela S Silva Santos, Viren A Baharani, Brianna Hernandez, Malcolm A Martin

bioRxiv· June 2025

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Safety, pharmacokinetics, and biological activity of CD4-mimetic BNM-III-170 in SHIV-infected rhesus macaques.
Elise G Viox, Jonathan Richard, Andres G Grandea, Kevin Nguyen, Justin Harper, Malcolm A Martin

J Virol· May 2025

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Administration of anti-HIV-1 broadly neutralizing monoclonal antibodies with increased affinity to Fcγ receptors during acute SHIV infection.
Joana Dias, Giulia Fabozzi, Slim Fourati, Xuejun Chen, Cuiping Liu, Malcolm A Martin

Nat Commun· August 2024

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Induction of durable remission by dual immunotherapy in SHIV-infected ART-suppressed macaques.
So-Yon Lim, Jina Lee, Christa E Osuna, Pratik Vikhe, Dane R Schalk, Malcolm Martin

Science· March 2024

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A Multilingual Digital Mental Health and Well-Being Chatbot (ChatPal): Pre-Post Multicenter Intervention Study.
Courtney Potts, Frida Lindström, Raymond Bond, Maurice Mulvenna, Frederick Booth, Martin Malcolm

J Med Internet Res· July 2023

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Online art therapy pilot in the Western Isles of Scotland: a feasibility and acceptability study of a novel service in a rural community.
Ania Zubala, Nicola Kennell, Catriona MacInnes, Marion MacInnes, Martin Malcolm

Front Psychiatry· May 2023

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CD4 binding site immunogens elicit heterologous anti-HIV-1 neutralizing antibodies in transgenic and wild-type animals.
Harry B Gristick, Harald Hartweger, Maximilian Loewe, Jelle van Schooten, Victor Ramos, Malcolm A Martin

Sci Immunol· February 2023

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Gene Editing of Primary Rhesus Macaque B Cells.
Harald Hartweger, Rajeev Gautam, Yoshiaki Nishimura, Fabian Schmidt, Kai-Hui Yao, Malcolm A Martin

J Vis Exp· February 2023

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Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer.
Zhi Yang, Kim-Marie A Dam, Michael D Bridges, Magnus A G Hoffmann, Andrew T DeLaitsch, Malcolm A Martin

Nat Commun· February 2022

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Sequential immunization of macaques elicits heterologous neutralizing antibodies targeting the V3-glycan patch of HIV-1 Env.
Amelia Escolano, Harry B Gristick, Rajeev Gautam, Andrew T DeLaitsch, Morgan E Abernathy, Malcolm A Martin

Sci Transl Med· November 2021

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Antibody elicited by HIV-1 immunogen vaccination in macaques displaces Env fusion peptide and destroys a neutralizing epitope.
Morgan E Abernathy, Harry B Gristick, Jost Vielmetter, Jennifer R Keeffe, Priyanthi N P Gnanapragasam, Malcolm A Martin

NPJ Vaccines· October 2021

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Concordance of immunological events between intrarectal and intravenous SHIVAD8-EO infection when assessed by Fiebig-equivalent staging.
Joana Dias, Giulia Fabozzi, Kylie March, Mangaiarkarasi Asokan, Cassandra G Almasri, Malcolm A Martin

J Clin Invest· September 2021

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Immunotherapy during the acute SHIV infection of macaques confers long-term suppression of viremia.
Yoshiaki Nishimura, Olivia K Donau, Joana Dias, Sara Ferrando-Martinez, Eric Jesteadt, Malcolm A Martin

J Exp Med· January 2021

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A broadly neutralizing macaque monoclonal antibody against the HIV-1 V3-Glycan patch.
Zijun Wang, Christopher O Barnes, Rajeev Gautam, Julio C Cetrulo Lorenzi, Christian T Mayer, Malcolm Martin

Elife· October 2020

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Prevention and treatment of SHIVAD8 infection in rhesus macaques by a potent d-peptide HIV entry inhibitor.
Yoshiaki Nishimura, J Nicholas Francis, Olivia K Donau, Eric Jesteadt, Reza Sadjadpour, Malcolm A Martin

Proc Natl Acad Sci U S A· September 2020

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Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.
Amelia Escolano, Harry B Gristick, Morgan E Abernathy, Julia Merkenschlager, Rajeev Gautam, Malcolm A Martin

Nature· June 2019

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Loneliness and social isolation causal association with health-related lifestyle risk in older adults: a systematic review and meta-analysis protocol.
Martin Malcolm, Helen Frost, Julie Cowie

Syst Rev· February 2019

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A single injection of crystallizable fragment domain-modified antibodies elicits durable protection from SHIV infection.
Rajeev Gautam, Yoshiaki Nishimura, Natalie Gaughan, Anna Gazumyan, Till Schoofs, Malcolm A Martin

Nat Med· May 2018

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Potential of conventional & bispecific broadly neutralizing antibodies for prevention of HIV-1 subtype A, C & D infections.
Kshitij Wagh, Michael S Seaman, Marshall Zingg, Tomas Fitzsimons, Dan H Barouch, Malcolm A Martin

PLoS Pathog· March 2018

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Of Mice, Macaques, and Men: Broadly Neutralizing Antibody Immunotherapy for HIV-1.
Yoshiaki Nishimura, Malcolm A Martin

Cell Host Microbe· August 2017

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