Publications by authors named "Malcolm White"

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An updated evolutionary classification of CRISPR-Cas systems including rare variants.
Kira S Makarova, Sergey A Shmakov, Yuri I Wolf, Pascal Mutz, Han Altae-Tran, Malcolm F White

Nat Microbiol· December 2025

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Structure and mechanism of the broad spectrum CRISPR-associated ring nuclease Crn4.
Haotian Chi, Ville Hoikkala, Stephen McMahon, Shirley Graham, Tracey Gloster, Malcolm F White

Nat Commun· December 2025

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Bacteria use a decoy defence molecule to set a trap for viruses.
Malcolm F White

Nature· November 2025

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A viral SAVED protein with ring nuclease activity degrades the CRISPR second messenger cA4.
Marta Orzechowski, Ville Hoikkala, Haotian Chi, Stephen McMahon, Tracey Gloster, Malcolm F White

Biochem J· November 2025

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Understanding internet-supported self-management for low back pain in primary care: a qualitative process evaluation of the SupportBack 2 randomised controlled trial.
Adam W A Geraghty, Stephanie Hughes, Lisa Roberts, Jonathan C Hill, Nadine E Foster, Malcolm White

BMJ Open· October 2025

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Solanum bulbocastanum nucleotide-binding leucine-rich repeat receptor evolution reveals functional variants and critical residues in Rpi-blb1/RB.
Jie Li, Sophie Mantelin, Miles Armstrong, Amanpreet Kaur, Sonia Gomez, Malcolm F White

J Integr Plant Biol· September 2025

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Diversity and abundance of ring nucleases in type III CRISPR-Cas loci.
Ville Hoikkala, Haotian Chi, Sabine Grüschow, Shirley Graham, Malcolm F White

Philos Trans R Soc Lond B Biol Sci· September 2025

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SAM-AMP lyases in type III CRISPR defence.
Haotian Chi, Stephen McMahon, Lukas Daniel-Pedersen, Shirley Graham, Tracey M Gloster, Malcolm F White

Nucleic Acids Res· July 2025

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Supporting self-management with an internet intervention for low back pain in primary care: a RCT (SupportBack 2).
Adam W A Geraghty, Taeko Becque, Lisa C Roberts, Jonathan Hill, Nadine E Foster, Malcolm White

Health Technol Assess· April 2025

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Reply to: Natively expressed AcrIII-1 does not function as an anti-CRISPR protein.
Januka S Athukoralage, Stephen A McMahon, Changyi Zhang, Sabine Grüschow, Shirley Graham, Malcolm F White

Nature· April 2025

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Cas10 based 7SL-sRNA diagnostic for the detection of active trypanosomosis.
Sabine Grüschow, Pieter C Steketee, Edith Paxton, Keith R Matthews, Liam J Morrison, Malcolm F White

PLoS Negl Trop Dis· March 2025

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Induced seismicity and geothermal energy production in the Salton Sea Geothermal Field, California.
Malcolm C A White, Nori Nakata

Sci Rep· January 2025

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Bioinformatic analysis of type III CRISPR systems reveals key properties and new effector families.
Ville Hoikkala, Shirley Graham, Malcolm F White

Nucleic Acids Res· July 2024

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Supporting self-management of low back pain with an internet intervention with and without telephone support in primary care (SupportBack 2): a randomised controlled trial of clinical and cost-effectiveness.
Adam W A Geraghty, Taeko Becque, Lisa C Roberts, Jonathan C Hill, Nadine E Foster, Malcolm White

Lancet Rheumatol· July 2024

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Reversible conjugation of a CBASS nucleotide cyclase regulates bacterial immune response to phage infection.
Larissa Krüger, Laura Gaskell-Mew, Shirley Graham, Sally Shirran, Robert Hertel, Malcolm F White

Nat Microbiol· June 2024

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RNA processing by the CRISPR-associated NYN ribonuclease.
Haotian Chi, Malcolm F White

Biochem J· June 2024

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Multi-layered genome defences in bacteria.
Aleksei Agapov, Kate S Baker, Paritosh Bedekar, Rama P Bhatia, Tim R Blower, Malcolm F White

Curr Opin Microbiol· April 2024

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CRISPR antiphage defence mediated by the cyclic nucleotide-binding membrane protein Csx23.
Sabine Grüschow, Stuart McQuarrie, Katrin Ackermann, Stephen McMahon, Bela E Bode, Malcolm F White

Nucleic Acids Res· April 2024

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Activation of Csm6 ribonuclease by cyclic nucleotide binding: in an emergency, twist to open.
Stuart McQuarrie, Januka S Athukoralage, Stephen A McMahon, Shirley Graham, Katrin Ackermann, Malcolm F White

Nucleic Acids Res· October 2023

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Antiviral type III CRISPR signalling via conjugation of ATP and SAM.
Haotian Chi, Ville Hoikkala, Sabine Grüschow, Shirley Graham, Sally Shirran, Malcolm F White

Nature· October 2023

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Repurposing the atypical type I-G CRISPR system for bacterial genome engineering.
Qilin Shangguan, Malcolm F White

Microbiology (Reading)· August 2023

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Antiviral signalling by a cyclic nucleotide activated CRISPR protease.
Christophe Rouillon, Niels Schneberger, Haotian Chi, Katja Blumenstock, Stefano Da Vela, Malcolm F White

Nature· February 2023

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Author Correction: Cyclic nucleotide-induced helical structure activates a TIR immune effector.
Gaëlle Hogrel, Abbie Guild, Shirley Graham, Hannah Rickman, Sabine Grüschow, Malcolm F White

Nature· February 2023

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Structure of the type III-D CRISPR effector.
Giuseppe Cannone, Dmytro Kompaniiets, Shirley Graham, Malcolm F White, Laura Spagnolo

Curr Res Struct Biol· February 2023

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Structure and mechanism of the type I-G CRISPR effector.
Qilin Shangguan, Shirley Graham, Ramasubramanian Sundaramoorthy, Malcolm F White

Nucleic Acids Res· October 2022

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