Publications by authors named "Manabu Koike"

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Canine Ku70 requires binding between its nuclear localization signal and nuclear pore-targeting complex for nuclear localization.
Manabu Koike, Togo Ikuta, Aki Koike

J Vet Med Sci· September 2025

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Molecular cloning, subcellular localization, and rapid recruitment to DNA damage sites of chicken Ku70.
Manabu Koike, Hideji Yamashita, Yasutomo Yutoku, Aki Koike

Sci Rep· January 2024

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Acetylation of the nuclear localization signal in Ku70 diminishes the interaction with importin-α.
Hirofumi Fujimoto, Togo Ikuta, Aki Koike, Manabu Koike

Biochem Biophys Rep· March 2023

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Combined ataxia telangiectasia mutated and DNA-dependent protein kinase inhibition radiosensitizes Madin-Darby canine kidney cells.
Manabu Koike, Yasutomo Yutoku, Aki Koike

J Vet Med Sci· November 2022

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Feline XRCC4 undergoes rapid Ku-dependent recruitment to DNA damage sites.
Manabu Koike, Yasutomo Yutoku, Aki Koike

FEBS Open Bio· April 2022

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Detection of double-stranded DNA breaks and apoptosis induced by bleomycin in mouse intestine.
Togo Ikuta, Aki Koike, Manabu Koike

J Toxicol Sci· January 2022

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Inhibition of Crandell-Rees Feline Kidney cell proliferation by X-ray-induced senescence.
Manabu Koike, Yasutomo Yutoku, Aki Koike

J Vet Med Sci· May 2021

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Combined deletions of IHH and NHEJ1 cause chondrodystrophy and embryonic lethality in the Creeper chicken.
Keiji Kinoshita, Takayuki Suzuki, Manabu Koike, Chizuko Nishida, Aki Koike

Commun Biol· March 2020

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Feline XLF accumulates at DNA damage sites in a Ku-dependent manner.
Manabu Koike, Yasutomo Yutoku, Aki Koike

FEBS Open Bio· June 2019

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ATF7 mediates TNF-α-induced telomere shortening.
Toshio Maekawa, Binbin Liu, Daisuke Nakai, Keisuke Yoshida, Ken-Ichi Nakamura, Manabu Koike

Nucleic Acids Res· May 2018

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Novel function of HATs and HDACs in homologous recombination through acetylation of human RAD52 at double-strand break sites.
Takeshi Yasuda, Wataru Kagawa, Tomoo Ogi, Takamitsu A Kato, Takehiro Suzuki, Manabu Koike

PLoS Genet· March 2018

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Cloning of canine Ku80 and its localization and accumulation at DNA damage sites.
Manabu Koike, Yasutomo Yutoku, Aki Koike

FEBS Open Bio· December 2017

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Cloning, localization and focus formation at DNA damage sites of canine Ku70.
Manabu Koike, Yasutomo Yutoku, Aki Koike

J Vet Med Sci· March 2017

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Cloning, localization and focus formation at DNA damage sites of canine XRCC4.
Manabu Koike, Yasutomo Yutoku, Aki Koike

J Vet Med Sci· January 2017

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Cloning, localization and focus formation at DNA damage sites of canine XLF.
Manabu Koike, Yasutomo Yutoku, Aki Koike

J Vet Med Sci· January 2017

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Dynamic changes in subcellular localization of cattle XLF during cell cycle, and focus formation of cattle XLF at DNA damage sites immediately after irradiation.
Manabu Koike, Yasutomo Yutoku, Aki Koike

J Vet Med Sci· September 2015

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Nuclear localization of mouse Ku70 in interphase cells and focus formation of mouse Ku70 at DNA damage sites immediately after irradiation.
Manabu Koike, Yasutomo Yutoku, Aki Koike

J Vet Med Sci· September 2015

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Impact of amino acid substitutions in two functional domains of Ku80: DNA-damage-sensing ability of Ku80 and survival after irradiation.
Manabu Koike, Yasutomo Yutoku, Aki Koike

J Vet Med Sci· January 2014

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Ku80 attentuates cytotoxicity induced by green fluorescent protein transduction independently of non-homologous end joining.
Manabu Koike, Yasutomo Yutoku, Aki Koike

FEBS Open Bio· June 2013

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The defect of Ku70 affects sensitivity to x-ray and radiation-induced caspase-dependent apoptosis in lung cells.
Manabu Koike, Yasutomo Yutoku, Aki Koike

J Vet Med Sci· May 2013

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The C-terminal region of Rad52 is essential for Rad52 nuclear and nucleolar localization, and accumulation at DNA damage sites immediately after irradiation.
Manabu Koike, Yasutomo Yutoku, Aki Koike

Biochem Biophys Res Commun· May 2013

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Establishment of hamster cell lines with EGFP-tagged human XRCC4 and protection from low-dose X-ray radiation.
Manabu Koike, Yasutomo Yutoku, Aki Koike

J Vet Med Sci· October 2012

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A possible overestimation of the effect of acetylation on lysine residues in KQ mutant analysis.
Hirofumi Fujimoto, Mariko Higuchi, Manabu Koike, Hirotaka Ode, Miroslav Pinak

J Comput Chem· January 2012

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Accumulation of Ku70 at DNA double-strand breaks in living epithelial cells.
Manabu Koike, Yasutomo Yutoku, Aki Koike

Exp Cell Res· October 2011

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Accumulation of p21 proteins at DNA damage sites independent of p53 and core NHEJ factors following irradiation.
Manabu Koike, Yasutomo Yutoku, Aki Koike

Biochem Biophys Res Commun· August 2011

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