Publications by authors named "Manching Ku"

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Dynamic WNT signaling controls differentiation of hematopoietic progenitor cells from human pluripotent stem cells.
Mo Li, Keiichiro Suzuki, Mengge Wang, Christopher Benner, Manching Ku

Sci China Life Sci· October 2025

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Characterisation of an autochthonous mouse ccRCC model of immune checkpoint inhibitor therapy resistance.
Asin Peighambari, Hsin Huang, Patrick Metzger, Mojca Adlesic, Kyra Zodel, Manching Ku

Sci Rep· June 2025

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TGF-β signaling redirects Sox11 gene regulatory activity to promote partial EMT and collective invasion of oncogenically transformed intestinal organoids.
Yu-Hsiang Teng, Bismark Appiah, Geoffroy Andrieux, Monika Schrempp, Katja Rose, Manching Ku

Oncogenesis· May 2025

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Integrative metabolomics-genomics analysis identifies key networks in a stem cell-based model of schizophrenia.
Angeliki Spathopoulou, Gabriella A Sauerwein, Valentin Marteau, Martina Podlesnic, Theresa Lindlbauer, Marja Koskuvi, Manching Ku, Markku Lähteenvuo

Mol Psychiatry· October 2024

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Exhaustion of CD39-Expressing CD8 T Cells in Crohn's Disease Is Linked to Clinical Outcome.
Anna-Maria Globig, Lena Sophie Mayer, Maximilian Heeg, Geoffroy Andrieux, Manching Ku, Armin Kuellmer

Gastroenterology· October 2022

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Author Correction: Wiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicing.
Baolei Yuan, Xuan Zhou, Keiichiro Suzuki, Gerardo Ramos-Mandujano, Mengge Wang, Manching Ku

Nat Commun· September 2022

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Spatially resolved multi-omics deciphers bidirectional tumor-host interdependence in glioblastoma.
Vidhya M Ravi, Paulina Will, Jan Kueckelhaus, Na Sun, Kevin Joseph, Ugne Kuliesiute, Manching Ku

Cancer Cell· June 2022

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Wiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicing.
Baolei Yuan, Xuan Zhou, Keiichiro Suzuki, Gerardo Ramos-Mandujano, Mengge Wang, Manching Ku

Nat Commun· June 2022

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Publisher Correction: Clinical evolution, genetic landscape and trajectories of clonal hematopoiesis in SAMD9/SAMD9L syndromes.
Sushree S Sahoo, Victor B Pastor, Charnise Goodings, Rebecca K Voss, Emilia J Kozyra, Markus Schmugge, Manching Ku

Nat Med· December 2021

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Dynamic transcriptome analysis reveals signatures of paradoxical effect of vemurafenib on human dermal fibroblasts.
Eyleen Corrales, Ella Levit-Zerdoun, Patrick Metzger, Silke Kowar, Manching Ku

Cell Commun Signal· December 2021

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Clinical evolution, genetic landscape and trajectories of clonal hematopoiesis in SAMD9/SAMD9L syndromes.
Sushree S Sahoo, Victor B Pastor, Charnise Goodings, Rebecca K Voss, Emilia J Kozyra, Markus Schmugge, Manching Ku

Nat Med· October 2021

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Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer's patients.
Jerome Mertens, Joseph R Herdy, Larissa Traxler, Simon T Schafer, Johannes C M Schlachetzki, Manching Ku

Cell Stem Cell· September 2021

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Negative correlation of single-cell expression with tumorigenicity in rhabdomyosarcoma.
Carla Regina, Ebrahem Hamed, Geoffroy Andrieux, Sina Angenendt, Michaela Schneider, Manching Ku, Ken Kikuchi

Life Sci Alliance· September 2021

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Prediabetes Induced by a Single Autoimmune B Cell Clone.
Nathaniel Phillips, Eugene Ke, Amy Nham, Maximilian Seidl, Brent Freeman, Manching Ku

Front Immunol· March 2021

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Single-cell transcriptomics uncover distinct innate and adaptive cell subsets during tissue homeostasis and regeneration.
Kevin Y Yang, Manching Ku, Kathy O Lui

J Leukoc Biol· November 2020

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Single-Cell RNA-Seq Reveals that CD9 Is a Negative Marker of Glucose-Responsive Pancreatic β-like Cells Derived from Human Pluripotent Stem Cells.
Xisheng Li, Kevin Y Yang, Vicken W Chan, Kam Tong Leung, Xiao-Bing Zhang, Manching Ku

Stem Cell Reports· November 2020

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Premature Activation of Immune Transcription Programs in Autoimmune-Predisposed Mouse Embryonic Stem Cells and Blastocysts.
Oktay Kirak, Eugene Ke, Kevin Y Yang, Anna Schwarz, Lars Plate, Manching Ku

Int J Mol Sci· August 2020

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Extraction of Distinct Neuronal Cell Types from within a Genetically Continuous Population.
Euiseok J Kim, Zhuzhu Zhang, Ling Huang, Tony Ito-Cole, Matthew W Jacobs, Manching Ku

Neuron· July 2020

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MicroRNA-146a regulates immune-related adverse events caused by immune checkpoint inhibitors.
Dominik Marschner, Martina Falk, Nora Rebeka Javorniczky, Kathrin Hanke-Müller, Justyna Rawluk, Manching Ku

JCI Insight· March 2020

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Chemical modulation of transcriptionally enriched signaling pathways to optimize the conversion of fibroblasts into neurons.
Joseph Herdy, Simon Schafer, Yongsung Kim, Zoya Ansari, Dina Zangwill, Manching Ku

Elife· May 2019

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Pathological priming causes developmental gene network heterochronicity in autistic subject-derived neurons.
Simon T Schafer, Apua C M Paquola, Shani Stern, David Gosselin, Manching Ku, Thomas J M Kuret

Nat Neurosci· February 2019

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Deconstructive somatic cell nuclear transfer reveals novel regulatory T-cell subsets.
Manching Ku, Eugene Ke, Mohsen Sabouri-Ghomi, Justin R Abadejos, Brent Freeman

J Allergy Clin Immunol· September 2018

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Single-cell transcriptomics reveal that PD-1 mediates immune tolerance by regulating proliferation of regulatory T cells.
Cherry S Leung, Kevin Y Yang, Xisheng Li, Vicken W Chan, Manching Ku

Genome Med· September 2018

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Regulatory T Cells Promote Apelin-Mediated Sprouting Angiogenesis in Type 2 Diabetes.
Oscar M Leung, Jiatao Li, Xisheng Li, Vicken W Chan, Kevin Y Yang, Manching Ku

Cell Rep· August 2018

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Mitochondrial Aging Defects Emerge in Directly Reprogrammed Human Neurons due to Their Metabolic Profile.
Yongsung Kim, Xinde Zheng, Zoya Ansari, Mark C Bunnell, Joseph R Herdy, Manching Ku

Cell Rep· May 2018

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