Publications by authors named "Mandy Aust"

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Co-administration of the mTORC1/TORC2 inhibitor INK128 and the Bcl-2/Bcl-xL antagonist ABT-737 kills human myeloid leukemia cells through Mcl-1 down-regulation and AKT inactivation.
Mohamed Rahmani, Mandy Mayo Aust, Elisa Hawkins, Rebecca E Parker, Masey Ross

Haematologica· December 2015

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Depletion of the chromatin remodeler CHD4 sensitizes AML blasts to genotoxic agents and reduces tumor formation.
Justin Sperlazza, Mohamed Rahmani, Jason Beckta, Mandy Aust, Elisa Hawkins

Blood· September 2015

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PI3K/mTOR inhibition markedly potentiates HDAC inhibitor activity in NHL cells through BIM- and MCL-1-dependent mechanisms in vitro and in vivo.
Mohamed Rahmani, Mandy Mayo Aust, Elisa C Benson, LaShanale Wallace, Jonathan Friedberg

Clin Cancer Res· September 2014

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Dual inhibition of Bcl-2 and Bcl-xL strikingly enhances PI3K inhibition-induced apoptosis in human myeloid leukemia cells through a GSK3- and Bim-dependent mechanism.
Mohamed Rahmani, Mandy Mayo Aust, Elisa Attkisson, David C Williams, Andrea Ferreira-Gonzalez

Cancer Res· February 2013

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Inhibition of Bcl-2 antiapoptotic members by obatoclax potently enhances sorafenib-induced apoptosis in human myeloid leukemia cells through a Bim-dependent process.
Mohamed Rahmani, Mandy Mayo Aust, Elisa Attkisson, David C Williams, Andrea Ferreira-Gonzalez

Blood· June 2012

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