Publications by authors named "Mandy van Brakel"

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CXCL10 Secreted by Pericytes Mediates TNFα-Induced Vascular Leakage in Tumors and Enhances Extravasation of Nanoparticle-Based Chemotherapeutics.
Ann L B Seynhaeve, Hui Liu, Marjolein I Priester, Mike Valentijn, Conny van Holten-Neelen, Mandy van Brakel

Cancer Res· May 2025

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TCR-Engineered T Cells Directed against Ropporin-1 Constitute a Safe and Effective Treatment for Triple-Negative Breast Cancer.
Dian Kortleve, Dora Hammerl, Mandy van Brakel, Rebecca Wijers, Daphne Roelofs

Cancer Discov· December 2024

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A blood-based immune marker for resistance to pembrolizumab in patients with metastatic urothelial cancer.
Maud Rijnders, Debbie G J Robbrecht, Astrid A M Oostvogels, Mandy van Brakel, Joost L Boormans

Cancer Immunol Immunother· March 2023

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Gene Engineering T Cells with T-Cell Receptor for Adoptive Therapy.
Dian Kortleve, Mandy van Brakel, Rebecca Wijers, Reno Debets, Dora Hammerl

Methods Mol Biol· May 2022

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Germline Variation in Is Associated with Overall Survival in Patients with Metastatic Melanoma Treated with Anti-PD-1 Monotherapy.
Mirjam de With, Daan P Hurkmans, Esther Oomen-de Hoop, Ayoub Lalouti, Sander Bins, Mandy van Brakel

Cancers (Basel)· March 2021

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Blood-based kinase activity profiling: a potential predictor of response to immune checkpoint inhibition in metastatic cancer.
Daan P Hurkmans, Els M E Verdegaal, Sabrina A Hogan, Rik de Wijn, Lies Hovestad, Mandy van Brakel

J Immunother Cancer· December 2020

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T Cells Expressing a TCR-Like Antibody Selected Against the Heteroclitic Variant of a Shared MAGE-A Epitope Do Not Recognise the Cognate Epitope.
Mesha Saeed, Erik Schooten, Mandy van Brakel, David K Cole, Timo L M Ten Hagen

Cancers (Basel)· May 2020

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Lack of B and T cell reactivity towards IDH1 in blood and tumor tissue from LGG patients.
Bas Weenink, Mandy van Brakel, Rebecca Wijers, Peter A E Sillevis Smitt, Pim J French

J Neurooncol· August 2019

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CD45RACCR7 CD8 T cells lacking co-stimulatory receptors demonstrate enhanced frequency in peripheral blood of NSCLC patients responding to nivolumab.
Andre Kunert, Edwin A Basak, Daan P Hurkmans, Hayri E Balcioglu, Yarne Klaver, Mandy van Brakel

J Immunother Cancer· June 2019

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Targeting melanoma with immunoliposomes coupled to anti-MAGE A1 TCR-like single-chain antibody.
Mesha Saeed, Mandy van Brakel, Sara Zalba, Erik Schooten, Joost A P Rens

Int J Nanomedicine· October 2016

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MAGE-C2-Specific TCRs Combined with Epigenetic Drug-Enhanced Antigenicity Yield Robust and Tumor-Selective T Cell Responses.
Andre Kunert, Mandy van Brakel, Sabine van Steenbergen-Langeveld, Marvin da Silva, Pierre G Coulie

J Immunol· September 2016

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Enhanced recruitment of genetically modified CX3CR1-positive human T cells into Fractalkine/CX3CL1 expressing tumors: importance of the chemokine gradient.
Imran Siddiqui, Marco Erreni, Mandy van Brakel, Reno Debets, Paola Allavena

J Immunother Cancer· April 2016

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T cell receptor-engineered T cells to treat solid tumors: T cell processing toward optimal T cell fitness.
Cor H J Lamers, Sabine van Steenbergen-Langeveld, Mandy van Brakel, Corrien M Groot-van Ruijven, Pascal M M L van Elzakker

Hum Gene Ther Methods· December 2014

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TCRs genetically linked to CD28 and CD3ε do not mispair with endogenous TCR chains and mediate enhanced T cell persistence and anti-melanoma activity.
Coen Govers, Zsolt Sebestyén, János Roszik, Mandy van Brakel, Cor Berrevoets

J Immunol· November 2014

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TCR gene transfer: MAGE-C2/HLA-A2 and MAGE-A3/HLA-DP4 epitopes as melanoma-specific immune targets.
Trudy Straetemans, Mandy van Brakel, Sabine van Steenbergen, Marieke Broertjes, Joost Drexhage

Clin Dev Immunol· March 2013

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