Publications by authors named "Manfred Grabner"

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Skeletal muscle delimited myopathy and verapamil toxicity in SUR2 mutant mouse models of AIMS.
Conor McClenaghan, Maya A Mukadam, Jacob Roeglin, Robert C Tryon, Manfred Grabner

EMBO Mol Med· June 2023

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The distal C terminus of the dihydropyridine receptor β subunit is essential for tetrad formation in skeletal muscle.
Anamika Dayal, Stefano Perni, Clara Franzini-Armstrong, Kurt G Beam, Manfred Grabner

Proc Natl Acad Sci U S A· May 2022

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Pore mutation N617D in the skeletal muscle DHPR blocks Ca influx due to atypical high-affinity Ca binding.
Anamika Dayal, Monica L Fernández-Quintero, Klaus R Liedl, Manfred Grabner

Elife· June 2021

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The mechanism underlying transient weakness in myotonia congenita.
Jessica H Myers, Kirsten Denman, Chris DuPont, Ahmed A Hawash, Kevin R Novak, Manfred Grabner

Elife· April 2021

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Divalent cations permeation in a Ca non-conducting skeletal muscle dihydropyridine receptor mouse model.
Romane Idoux, Clarisse Fuster, Vincent Jacquemond, Anamika Dayal, Manfred Grabner

Cell Calcium· November 2020

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Ca-activated Cl channel TMEM16A/ANO1 identified in zebrafish skeletal muscle is crucial for action potential acceleration.
Anamika Dayal, Shu Fun J Ng, Manfred Grabner

Nat Commun· January 2019

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Calcium Influx and Release Cooperatively Regulate AChR Patterning and Motor Axon Outgrowth during Neuromuscular Junction Formation.
Mehmet Mahsum Kaplan, Nasreen Sultana, Ariane Benedetti, Gerald J Obermair, Nina F Linde, Manfred Grabner

Cell Rep· June 2018

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The Ca influx through the mammalian skeletal muscle dihydropyridine receptor is irrelevant for muscle performance.
Anamika Dayal, Kai Schrötter, Yuan Pan, Karl Föhr, Werner Melzer, Manfred Grabner

Nat Commun· September 2017

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The mammalian skeletal muscle DHPR has larger Ca conductance and is phylogenetically ancient to the early ray-finned fish sterlet (Acipenser ruthenus).
Kai Schrötter, Anamika Dayal, Manfred Grabner

Cell Calcium· January 2017

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Two distinct voltage-sensing domains control voltage sensitivity and kinetics of current activation in CaV1.1 calcium channels.
Petronel Tuluc, Bruno Benedetti, Pierre Coste de Bagneaux, Manfred Grabner, Bernhard E Flucher

J Gen Physiol· June 2016

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Domain cooperativity in the β1a subunit is essential for dihydropyridine receptor voltage sensing in skeletal muscle.
Anamika Dayal, Vinayakumar Bhat, Clara Franzini-Armstrong, Manfred Grabner

Proc Natl Acad Sci U S A· April 2013

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Crosstalk via the Sarcoplasmic Gap: The DHPR-RyR Interaction.
Manfred Grabner, Anamika Dayal

Curr Top Membr· October 2012

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Identification and functional characterization of malignant hyperthermia mutation T1354S in the outer pore of the Cavalpha1S-subunit.
Antonella Pirone, Johann Schredelseker, Petronel Tuluc, Elvira Gravino, Giuliana Fortunato, Manfred Grabner

Am J Physiol Cell Physiol· December 2010

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Skeletal muscle excitation-contraction coupling is independent of a conserved heptad repeat motif in the C-terminus of the DHPRbeta(1a) subunit.
Anamika Dayal, Johann Schredelseker, Clara Franzini-Armstrong, Manfred Grabner

Cell Calcium· June 2010

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Non-Ca2+-conducting Ca2+ channels in fish skeletal muscle excitation-contraction coupling.
Johann Schredelseker, Manisha Shrivastav, Anamika Dayal, Manfred Grabner

Proc Natl Acad Sci U S A· March 2010

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Proper restoration of excitation-contraction coupling in the dihydropyridine receptor beta1-null zebrafish relaxed is an exclusive function of the beta1a subunit.
Johann Schredelseker, Anamika Dayal, Thorsten Schwerte, Clara Franzini-Armstrong, Manfred Grabner

J Biol Chem· January 2009

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The alpha(1S) III-IV loop influences 1,4-dihydropyridine receptor gating but is not directly involved in excitation-contraction coupling interactions with the type 1 ryanodine receptor.
Roger A Bannister, Manfred Grabner, Kurt G Beam

J Biol Chem· August 2008

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The role of auxiliary dihydropyridine receptor subunits in muscle.
Bernhard E Flucher, Gerald J Obermair, Petronel Tuluc, Johann Schredelseker, Georg Kern, Manfred Grabner

J Muscle Res Cell Motil· June 2006

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The beta 1a subunit is essential for the assembly of dihydropyridine-receptor arrays in skeletal muscle.
Johann Schredelseker, Valentina Di Biase, Gerald J Obermair, E Tatiana Felder, Bernhard E Flucher, Manfred Grabner

Proc Natl Acad Sci U S A· November 2005

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Functional interaction of CaV channel isoforms with ryanodine receptors studied in dysgenic myotubes.
Ralph Peter Schuhmeier, Elodie Gouadon, Daniel Ursu, Nicole Kasielke, Bernhard E Flucher, Manfred Grabner

Biophys J· March 2005

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The Ca2+ channel alpha2delta-1 subunit determines Ca2+ current kinetics in skeletal muscle but not targeting of alpha1S or excitation-contraction coupling.
Gerald J Obermair, Gerlinde Kugler, Sabine Baumgartner, Petronel Tuluc, Manfred Grabner

J Biol Chem· January 2005

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Differential contribution of skeletal and cardiac II-III loop sequences to the assembly of dihydropyridine-receptor arrays in skeletal muscle.
Hiroaki Takekura, Cecilia Paolini, Clara Franzini-Armstrong, Gerlinde Kugler, Manfred Grabner

Mol Biol Cell· December 2004

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Functional analysis of the R1086H malignant hyperthermia mutation in the DHPR reveals an unexpected influence of the III-IV loop on skeletal muscle EC coupling.
Regina G Weiss, Kristen M S O'Connell, Bernhard E Flucher, Paul D Allen, Manfred Grabner

Am J Physiol Cell Physiol· October 2004

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The monoclonal antibody mAB 1A binds to the excitation--contraction coupling domain in the II-III loop of the skeletal muscle calcium channel alpha(1S) subunit.
Gerlinde Kugler, Manfred Grabner, Josef Platzer, Jörg Striessnig, Bernhard E Flucher

Arch Biochem Biophys· July 2004

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Structural requirements of the dihydropyridine receptor alpha1S II-III loop for skeletal-type excitation-contraction coupling.
Gerlinde Kugler, Regina G Weiss, Bernhard E Flucher, Manfred Grabner

J Biol Chem· February 2004

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