Publications by authors named "Manfred Liebsch"

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The hen's egg test for micronucleus induction (HET-MN): validation data set.
Kerstin Reisinger, Dagmar Fieblinger, Andreas Heppenheimer, Jürgen Kreutz, Manfred Liebsch

Mutagenesis· May 2022

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Validation of the hen's egg test for micronucleus induction (HET-MN): detailed protocol including scoring atlas, historical control data and statistical analysis.
Katrin Maul, Dagmar Fieblinger, Andreas Heppenheimer, Juergen Kreutz, Manfred Liebsch

Mutagenesis· May 2022

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Evaluation of in vitro embryotoxicity tests for Chinese herbal medicines.
Lu Li, Ling Yin Tang, Bo Liang, Rongyun Wang, Qiuhua Sun, Manfred Liebsch

Reprod Toxicol· October 2019

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Fetal Bovine Serum (FBS): Past - Present - Future.
Jan van der Valk, Karen Bieback, Christiane Buta, Brett Cochrane, Wilhelm G Dirks, Manfred Liebsch

ALTEX· August 2018

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Validation of the 3D Skin Comet assay using full thickness skin models: Transferability and reproducibility.
Kerstin Reisinger, Veronika Blatz, Joep Brinkmann, Thomas R Downs, Anja Fischer, Manfred Liebsch

Mutat Res Genet Toxicol Environ Mutagen· March 2018

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Influence of massage and occlusion on the ex vivo skin penetration of rigid liposomes and invasomes.
Sindy Trauer, Heike Richter, Judith Kuntsche, Rolf Büttemeyer, Manfred Liebsch

Eur J Pharm Biopharm· February 2014

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Statistical analysis of the hen's egg test for micronucleus induction (HET-MN assay).
Ludwig A Hothorn, Kerstin Reisinger, Thorsten Wolf, Albrecht Poth, Dagmar Fieblinger, Manfred Liebsch

Mutat Res· September 2013

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Assessment of the predictive capacity of the 3T3 Neutral Red Uptake cytotoxicity test method to identify substances not classified for acute oral toxicity (LD50>2000 mg/kg): results of an ECVAM validation study.
Pilar Prieto, Thomas Cole, Rodger Curren, Rosemary M Gibson, Manfred Liebsch

Regul Toxicol Pharmacol· April 2013

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Skin phototoxicity of cosmetic formulations containing photounstable and photostable UV-filters and vitamin A palmitate.
Lorena R Gaspar, Julian Tharmann, Patricia M B G Maia Campos, Manfred Liebsch

Toxicol In Vitro· February 2013

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Metabolically competent human skin models: activation and genotoxicity of benzo[a]pyrene.
Joep Brinkmann, Kristin Stolpmann, Susanne Trappe, Timo Otter, Doris Genkinger, Manfred Liebsch

Toxicol Sci· February 2013

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Wind of change challenges toxicological regulators.
Tewes Tralau, Christian Riebeling, Ralph Pirow, Michael Oelgeschläger, Andrea Seiler, Manfred Liebsch

Environ Health Perspect· November 2012

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The 3T3 neutral red uptake phototoxicity test: practical experience and implications for phototoxicity testing--the report of an ECVAM-EFPIA workshop.
Mara Ceridono, Pär Tellner, Daniel Bauer, João Barroso, Nathalie Alépée, Manfred Liebsch

Regul Toxicol Pharmacol· August 2012

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Regulatory assessment of in vitro skin corrosion and irritation data within the European framework: Workshop recommendations.
Chantra Eskes, Véronique Detappe, Herman Koëter, Joachim Kreysa, Manfred Liebsch

Regul Toxicol Pharmacol· March 2012

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Developmental toxicity testing in the 21st century: the sword of Damocles shattered by embryonic stem cell assays?
Andrea Seiler, Michael Oelgeschläger, Manfred Liebsch, Ralph Pirow, Christian Riebeling

Arch Toxicol· November 2011

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Implementation and enforcement of the 3Rs principle in the field of transgenic animals used for scientific purposes. Report and recommendations of the BfR expert workshop, May 18-20, 2009, Berlin, Germany.
Ariane Kretlow, Daniel Butzke, Mario E Goetz, Barbara Grune, Marlies Halder, Manfred Liebsch

ALTEX· August 2011

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Alternatives to animal testing: current status and future perspectives.
Manfred Liebsch, Barbara Grune, Andrea Seiler, Daniel Butzke, Michael Oelgeschläger

Arch Toxicol· August 2011

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A knowledge-based search engine to navigate the information thicket of nanotoxicology.
Ursula G Sauer, Carsten Kneuer, Jutta Tentschert, Thomas Wächter, Michael Schroeder, Manfred Liebsch

Regul Toxicol Pharmacol· February 2011

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The current scientific and legal status of alternative methods to the LD50 test for botulinum neurotoxin potency testing. The report and recommendations of a ZEBET Expert Meeting.
Sarah Adler, Gerd Bicker, Hans Bigalke, Christopher Bishop, Jörg Blümel, Manfred Liebsch

Altern Lab Anim· August 2010

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Comparison of human skin irritation patch test data with in vitro skin irritation assays and animal data.
Dagmar Jírová, David Basketter, Manfred Liebsch, Hana Bendová, Kristina Kejlová

Contact Dermatitis· February 2010

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Permeation of topically applied caffeine through human skin--a comparison of in vivo and in vitro data.
Sindy Trauer, Alexa Patzelt, Nina Otberg, Fanny Knorr, Christel Rozycki, Manfred Liebsch

Br J Clin Pharmacol· August 2009

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In vitro models of inhalation toxicity and disease. The report of a FRAME workshop.
Kelly BéruBé, Michaela Aufderheide, Damien Breheny, Richard Clothier, Robert Combes, Manfred Liebsch

Altern Lab Anim· February 2009

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Points of reference in the validation process: the report and recommendations of ECVAM Workshop 66.
Sebastian Hoffmann, Lutz Edler, Ian Gardner, Laura Gribaldo, Thomas Hartung, Manfred Liebsch

Altern Lab Anim· July 2008

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Successful validation of in vitro methods in toxicology by ZEBET, the National Centre for Alternatives in Germany at the BfR (Federal Institute for Risk Assessment).
Horst Spielmann, Barbara Grune, Manfred Liebsch, Andrea Seiler, Richard Vogel

Exp Toxicol Pathol· June 2008

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The use of reconstructed human epidermis for skin absorption testing: Results of the validation study.
Monika Schäfer-Korting, Udo Bock, Walter Diembeck, Hans-Jürgen Düsing, Armin Gamer, Manfred Liebsch

Altern Lab Anim· May 2008

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The ECVAM international validation study on in vitro tests for acute skin irritation: report on the validity of the EPISKIN and EpiDerm assays and on the Skin Integrity Function Test.
Horst Spielmann, Sebastian Hoffmann, Manfred Liebsch, Phil Botham, Julia H Fentem

Altern Lab Anim· December 2007

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