Publications by authors named "Manfred Windisch"

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Randomized phase 2a trial assessing a novel septin molecular glue in Alzheimer's disease.
Mieke Nuytten, Marieke Voets, Eveline Debroux, Katrien Princen, Lentel Pringels, Manfred Windisch

Alzheimers Dement· September 2025

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p75 neurotrophin receptor modulation in mild to moderate Alzheimer disease: a randomized, placebo-controlled phase 2a trial.
Hayley R C Shanks, Kewei Chen, Eric M Reiman, Kaj Blennow, Jeffrey L Cummings, Manfred Windisch

Nat Med· June 2024

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Translational animal models for Alzheimer's disease: An Alzheimer's Association Business Consortium Think Tank.
Michael P Vitek, Joseph A Araujo, Michael Fossel, Barry D Greenberg, Gareth R Howell, Manfred Windisch

Alzheimers Dement (N Y)· January 2021

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Safety and pharmacokinetics of the orally available antiprionic compound PRI-002: A single and multiple ascending dose phase I study.
Janine Kutzsche, Dagmar Jürgens, Antje Willuweit, Knut Adermann, Carola Fuchs, Manfred Windisch

Alzheimers Dement (N Y)· March 2020

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BACE1-cleavage of Sez6 and Sez6L is elevated in Niemann-Pick type C disease mouse brains.
Mirsada Causevic, Kristina Dominko, Martina Malnar, Lea Vidatic, Stjepko Cermak, Manfred Windisch

PLoS One· January 2019

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Development of GMP-1 a molecular chaperone network modulator protecting mitochondrial function and its assessment in fly and mice models of Alzheimer's disease.
Pavel F Pavlov, Birgit Hutter-Paier, Daniel Havas, Manfred Windisch, Bengt Winblad

J Cell Mol Med· July 2018

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Adamantane - A Lead Structure for Drugs in Clinical Practice.
Katarina Spilovska, Filip Zemek, Jan Korabecny, Eugenie Nepovimova, Ondrej Soukup, Manfred Windisch

Curr Med Chem· February 2017

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Scopolamine disrupts place navigation in rats and humans: a translational validation of the Hidden Goal Task in the Morris water maze and a real maze for humans.
Jan Laczó, Hana Markova, Veronika Lobellova, Ivana Gazova, Martina Parizkova, Manfred Windisch

Psychopharmacology (Berl)· February 2017

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Preface.
Abraham Fisher, Roger M Nitsch, Manfred Windisch

Neurodegener Dis· September 2016

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Brain cortical cholesterol metabolism is highly affected by human APP overexpression in mice.
Tina Löffler, Cornelia Schweinzer, Stefanie Flunkert, Miklós Sántha, Manfred Windisch

Mol Cell Neurosci· July 2016

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Influence of Lentiviral β-Synuclein Overexpression in the Hippocampus of a Transgenic Mouse Model of Alzheimer's Disease on Amyloid Precursor Protein Metabolism and Pathology.
Stefanie Krassnig, Cornelia Schweinzer, Nicole Taub, Daniel Havas, Ewald Auer, Manfred Windisch

Neurodegener Dis· April 2016

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Late-stage α-synuclein accumulation in TNWT-61 mouse model of Parkinson's disease detected by diffusion kurtosis imaging.
Amit Khairnar, Jana Ruda-Kucerova, Eva Drazanova, Nikoletta Szabó, Peter Latta, Manfred Windisch

J Neurochem· March 2016

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Diffusion Kurtosis Imaging Detects Microstructural Alterations in Brain of α-Synuclein Overexpressing Transgenic Mouse Model of Parkinson's Disease: A Pilot Study.
Amit Khairnar, Peter Latta, Eva Drazanova, Jana Ruda-Kucerova, Nikoletta Szabó, Manfred Windisch

Neurotox Res· November 2015

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Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers I: Abeta 42 oligomer binding to specific neuronal receptors is displaced by drug candidates that improve cognitive deficits.
Nicholas J Izzo, Agnes Staniszewski, Lillian To, Mauro Fa, Andrew F Teich, Manfred Windisch

PLoS One· July 2015

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L-type calcium channel blockers and substance P induce angiogenesis of cortical vessels associated with beta-amyloid plaques in an Alzheimer mouse model.
Nina Daschil, Kathrin M Kniewallner, Gerald J Obermair, Birgit Hutter-Paier, Manfred Windisch

Neurobiol Aging· March 2015

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Tracking of magnetite labeled nanoparticles in the rat brain using MRI.
Naira P Martínez Vera, Reinhold Schmidt, Klaus Langer, Iavor Zlatev, Robert Wronski, Manfred Windisch

PLoS One· November 2014

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We can treat Alzheimer's disease successfully in mice but not in men: failure in translation? A perspective.
Manfred Windisch

Neurodegener Dis· September 2014

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Increased efflux of amyloid-β peptides through the blood-brain barrier by muscarinic acetylcholine receptor inhibition reduces pathological phenotypes in mouse models of brain amyloidosis.
Paolo Paganetti, Katia Antoniello, Kavi Devraj, Nicolas Toni, Dairin Kieran, Manfred Windisch

J Alzheimers Dis· August 2014

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Nanoparticulate flurbiprofen reduces amyloid-β42 generation in an in vitro blood-brain barrier model.
Sabrina Meister, Iavor Zlatev, Julia Stab, Dominic Docter, Sandra Baches, Manfred Windisch

Alzheimers Res Ther· May 2014

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Neuroinflammation and related neuropathologies in APPSL mice: further value of this in vivo model of Alzheimer's disease.
Tina Löffler, Stefanie Flunkert, Daniel Havas, Cornelia Schweinzer, Marni Uger, Manfred Windisch

J Neuroinflammation· May 2014

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CaV1.2 calcium channel expression in reactive astrocytes is associated with the formation of amyloid-β plaques in an Alzheimer's disease mouse model.
Nina Daschil, Gerald J Obermair, Bernhard E Flucher, Nadia Stefanova, Birgit Hutter-Paier, Manfred Windisch

J Alzheimers Dis· April 2014

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Impact of ApoB-100 expression on cognition and brain pathology in wild-type and hAPPsl mice.
Tina Löffler, Stefanie Flunkert, Daniel Havas, Miklós Sántha, Birgit Hutter-Paier, Manfred Windisch

Neurobiol Aging· October 2013

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Non-selective calcium channel blocker bepridil decreases secondary pathology in mice after photothrombotic cortical lesion.
Anu Lipsanen, Stefanie Flunkert, Kristina Kuptsova, Mikko Hiltunen, Manfred Windisch

PLoS One· September 2013

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The bivalent ligand approach as a tool for improving the in vitro anti-Alzheimer multitarget profile of dimebon.
Michela Rosini, Elena Simoni, Manuela Bartolini, Elena Soriano, José Marco-Contelles, Manfred Windisch

ChemMedChem· August 2013

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Time course and progression of wild type α-synuclein accumulation in a transgenic mouse model.
David Amschl, Jörg Neddens, Daniel Havas, Stefanie Flunkert, Roland Rabl, Manfred Windisch

BMC Neurosci· January 2013

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