Publications by authors named "Manfred Wuhrer"

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Altered glycosylation profile of anti-HPA-1a-specific antibodies: insights from a prospective fetal and neonatal alloimmune thrombocytopenia cohort.
Janita J Oosterhoff, Arthur E H Bentlage, David Falck, Wenjun Wang, Jan Nouta, Manfred Wuhrer

Haematologica· December 2025

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Plasma proteomic profiles of patients during oral anti-coagulant treatment with vitamin K antagonists.
Eleonora Camilleri, Bart J M van Vlijmen, Mettine H A Bos, Manfred Wuhrer, David R Goodlett

Br J Haematol· December 2025

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Patient-derived organoids to study glycosylation dynamics during gastric disease.
Liliana Santos-Ferreira, Álvaro M Martins, Henrique O Duarte, Eva Moia, Ana F Costa, Manfred Wuhrer

Cell Rep· November 2025

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Short Mucin-Type O-Glycans in Cancer: Biomarker and Therapeutic Potential amid Analytical Barriers.
Henrique Sousa, Inês A B Ribeiro, Marta Falcão, Daniela F Barreira, Mariana Barbosa, Manfred Wuhrer

Glycobiology· November 2025

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Decreased Fc fucosylation aligns with enhanced RSV-specific antibody functionality in adults compared to young children.
Anke J Lakerveld, Wenjun Wang, Rutger M Schepp, Jan Nouta, Steinar Gijze, Manfred Wuhrer

Commun Med (Lond)· November 2025

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Mass spectrometric analysis of lipid-linked oligosaccharide heterogeneity in genetically modified E. coli used for glycoconjugate bacterial vaccine production.
Ieva Palubeckaite, Alan B Moran, Dario A T Cramer, Anabel Torrente-López, Wiep Klaas Smits, Manfred Wuhrer

Carbohydr Polym· October 2025

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Anti-tumor vaccine efficacy depends on adjuvant type and associates with induced IgG subclass and glycosylation profiles.
Selina Lehrian, Anna Wasynczuk, Janina Petry, Melanie Guderian, Jan Nouta, Manfred Wuhrer

Exp Hematol Oncol· October 2025

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IgG-Fc Glycosylation and a Novel Flowcytometric Assay to Predict Hemolytic Disease of the Fetus and Newborn.
Derek P de Winter, Thijs L J van Osch, Remco Visser, Tessa Vreeswijk, Zoltán Szittner, Manfred Wuhrer

Transfus Med Hemother· October 2025

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Structural characterization of intact polysaccharides by MALDI-in-source decay-Fourier transform ion cyclotron resonance (FTICR) MS.
Yasmin van der Velden, Christoph Gstöttner, Constantin Blöchl, Leon Coulier, Adriana Carvalho de Souza, Manfred Wuhrer

Carbohydr Polym· September 2025

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Plasma -Glycan Signatures Are Associated With a First Event of Venous Thromboembolism.
Ruifang Li-Gao, Marco R Bladergroen, Frits R Rosendaal, Manfred Wuhrer, Astrid van Hylckama Vlieg

Arterioscler Thromb Vasc Biol· September 2025

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Modulation of immunoglobulin G oligomerization by variable domain glycans: A mechanism to regulate complement activation.
Roxane Biersteker, Leoni Abendstein, Sanne van de Bovenkamp, Hugo J van Dooren, Sebastiaan M W R Hamers, Manfred Wuhrer

PNAS Nexus· July 2025

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Intra-Host Evolution During Relapsing Parvovirus B19 Infection in Immunocompromised Patients.
Anne Russcher, Yassene Mohammed, Margriet E M Kraakman, Xavier Chow, Stijn T Kok, Manfred Wuhrer

Viruses· July 2025

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Enhancing activity of FcαRI-bispecific antibodies using glycoengineering.
Céline A N Sewnath, Timon Damelang, Arthur E H Bentlage, Luuk Ten Kroode, Cornelis W Tuk, Manfred Wuhrer

J Immunol· June 2025

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Variable domain glycosylation as a marker and modulator of immune responses: Insights into autoimmunity and B-cell malignancies.
Roxane Biersteker, Oliver F Larsen, Manfred Wuhrer, Tom W J Huizinga, René E M Toes

Semin Immunol· June 2025

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Systems analysis unravels a common rural-urban gradient in immunological profile, function, and metabolic dependencies.
Mikhael D Manurung, Graham A Heieis, Marion König, Shohreh Azimi, Malick Ndao, Manfred Wuhrer

Sci Adv· May 2025

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Protein N-Glycosylation Traits Combined with CA19-9 Accurately Distinguish Pancreatic Cancer Cases From Healthy Controls and Benign Pancreatic Diseases.
Aleksander M Bogdanski, Derk C F Klatte, Monique E van Leerdam, Christa M Cobbaert, Bart E P B Ballieux, Manfred Wuhrer

Pancreas· May 2025

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Sera contributing to mycobacterial growth restriction display enhanced Fc-mediated phagocytosis.
Krista E van Meijgaarden, Patricia S Grace, Wenjun Wang, Delia Goletti, Fabrizio Palmieri, Manfred Wuhrer

iScience· May 2025

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Fc Proteoforms of ACPA IgG Discriminate Autoimmune Responses in Plasma and Synovial Fluid of Rheumatoid Arthritis Patients and Associate with Disease Activity.
Constantin Blöchl, Eva Maria Stork, Hans Ulrich Scherer, Rene E M Toes, Manfred Wuhrer

Adv Sci (Weinh)· April 2025

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Insight into distribution and composition of nonhuman N-Glycans in mammalian organs via MALDI-TOF and MALDI-MSI.
Rui-Rui Guo, Bram Heijs, Wen-Jun Wang, Manfred Wuhrer, Li Liu

Carbohydr Polym· March 2025

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Comprehensive Immunoglobulin G, A, and M Glycopeptide Profiling for Large-Scale Biomedical Research.
Bianca D M van Tol, Anna M Wasynczuk, Steinar Gijze, Oleg A Mayboroda, Jan Nouta, Manfred Wuhrer

Mol Cell Proteomics· March 2025

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Tumor-Expressed SPPL3 Supports Innate Antitumor Immune Responses.
Tamara Verkerk, Antonius A de Waard, Sofie J I Koomen, Jasper Sanders, Tineke Jorritsma, Manfred Wuhrer

Eur J Immunol· February 2025

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IgA displays site- and subclass-specific glycoform differences despite equal glycoenzyme expression.
David Falck, Maria V Sokolova, Carolien A M Koeleman, Vanessa Irumva, Philipp Kirchner, Manfred Wuhrer

Cell Commun Signal· February 2025

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Acquisition of Fc-afucosylation of PfEMP1-specific IgG is age-dependent and associated with clinical protection against malaria.
Mary Lopez-Perez, Zakaria Seidu, Mads Delbo Larsen, Wenjun Wang, Jan Nouta, Manfred Wuhrer

Nat Commun· January 2025

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Parasitic infections during pregnancy in Gabon affect glycosylation patterns of maternal and child antibodies.
Yabo J Honkpehedji, Anna O Kildemoes, Koen A Stam, Dieu L Nguyen, Tom Veldhuizen, Manfred Wuhrer

Sci Rep· December 2024

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ASGR1 deficiency improves atherosclerosis but alters liver metabolism in ApoE mice.
Monika Svecla, Annalisa Moregola, Lorenzo Da Dalt, Jasmine Nour, Andrea Baragetti, Manfred Wuhrer

Cardiovasc Diabetol· November 2024

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