Publications by authors named "Manikandan Lakshmanan"

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Depletion of BLOC1S1 with splice-switching oligonucleotides in ALS motor neurons improves mitochondrial respiration and rescues disease phenotypes.
Jin-Hui Hor, Jin Rong Ow, Winanto Ng, Boominathan Ramasamy, Tommaso Tabaglio, Manikandan Lakshmanan

Mol Ther· December 2025

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Double-Network Bioadhesives from Sustainable Plant Precursors.
Animesh Ghosh, Wu X Vicki, Jie J Ng, Darien Kwek, Elwin W J Ang, Manikandan Lakshmanan

ACS Appl Mater Interfaces· October 2025

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Aggressive B cell lymphomas retain ATR-dependent determinants of T cell exclusion from the germinal center dark zone.
Valeria Cancila, Giorgio Bertolazzi, Allison Sy Chan, Giovanni Medico, Giulia Bastianello, Manikandan Lakshmanan

J Clin Invest· September 2025

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Developing splice-switching oligonucleotides for urea cycle disorder using an integrated diagnostic and therapeutic platform.
Jin Rong Ow, Eri Imagawa, Feng Chen, Wei Yuan Cher, Shermin Yu Tung Chan, Manikandan Lakshmanan

J Hepatol· August 2025

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Unveiling sequence-agnostic mixed-chemical modification patterns for splice-switching oligonucleotides using the NATURA platform.
Tommaso Tabaglio, Taniya Agarwal, Wei Yuan Cher, Jin Rong Ow, Ah Keng Chew, Manikandan Lakshmanan

Mol Ther Nucleic Acids· March 2025

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Super-silencer perturbation by EZH2 and REST inhibition leads to large loss of chromatin interactions and reduction in cancer growth.
Ying Zhang, Kaijing Chen, Seng Chuan Tang, Yichao Cai, Akiko Nambu, Manikandan Lakshmanan

Nat Struct Mol Biol· January 2025

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GNA13 suppresses proliferation of ER+ breast cancer cells via ERα dependent upregulation of the MYC oncogene.
Lalitha Vaishnavi Subramanyan, Suhail Ahmed Kabeer Rasheed, Lijin Wang, Sujoy Ghosh, Michelle Shi Ning Ong, Manikandan Lakshmanan

Breast Cancer Res· July 2024

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Color changing bioadhesive barrier for peripherally inserted central catheters.
Ivan Djordjevic, Elizabeth Ellis, Juhi Singh, Naziruddin Ali, Edgar M Pena, Lakshmanan Manikandan

Biomater Sci· March 2024

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Mono-2-ethylhexylphthalate (MEHP) is a potent agonist of human TRPA1 channel.
Megan Goh, Lin Fu, Wei-Guang Seetoh, Ann Koay, Huang Hua, Manikandan Lakshmanan

Chemosphere· February 2024

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WNTinib is a multi-kinase inhibitor with specificity against β-catenin mutant hepatocellular carcinoma.
Alex Rialdi, Mary Duffy, Alex P Scopton, Frank Fonseca, Julia Nanyi Zhao, Manikandan Lakshmanan

Nat Cancer· August 2023

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Dependency of NELF-E-SLUG-KAT2B epigenetic axis in breast cancer carcinogenesis.
Jieqiong Zhang, Zhenhua Hu, Hwa Hwa Chung, Yun Tian, Kah Weng Lau, Manikandan Lakshmanan

Nat Commun· April 2023

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Correction: PLK1 inhibition selectively induces apoptosis in ARID1A deficient cells through uncoupling of oxygen consumption from ATP production.
Upadhyayula S Srinivas, Norbert S C Tay, Patrick Jaynes, Akshaya Anbuselvan, Gokula K Ramachandran, Manikandan Lakshmanan

Oncogene· June 2022

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PLK1 inhibition selectively induces apoptosis in ARID1A deficient cells through uncoupling of oxygen consumption from ATP production.
Upadhyayula S Srinivas, Norbert S C Tay, Patrick Jaynes, Akshaya Anbuselvan, Gokula K Ramachandran, Manikandan Lakshmanan

Oncogene· March 2022

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A rare presentation of solitary pineal region metastasis in a case of lung cancer.
Banupriya Mohan, Suresh Bapu, Ranjan Kumar Mahapatra, Manikandan Lakshmanan

J Cancer Res Ther· August 2021

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H3K27me3-rich genomic regions can function as silencers to repress gene expression via chromatin interactions.
Yichao Cai, Ying Zhang, Yan Ping Loh, Jia Qi Tng, Mei Chee Lim, Lakshmanan Manikandan

Nat Commun· January 2021

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Study of tumor transglutaminase 2 expression in gallbladder cancer - ?
Sameer Gupta, Sudeep Garg, Vijay Kumar, Arun Chaturvedi, Sanjeev Misra, Manikandan Lakshmanan

Ann Hepatobiliary Pancreat Surg· November 2020

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Targeting N-myristoylation for therapy of B-cell lymphomas.
Erwan Beauchamp, Megan C Yap, Aishwarya Iyer, Maneka A Perinpanayagam, Jay M Gamma, Manikandan Lakshmanan

Nat Commun· October 2020

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Validation of the Brandwein Gensler Risk Model in Patients of Oral Cavity Squamous Cell Carcinoma in North India.
Arun Chaturvedi, Nuzhat Husain, Sanjeev Misra, Vijay Kumar, Sameer Gupta, Manikandan Lakshmanan

Head Neck Pathol· September 2020

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PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis.
Slim Mzoughi, Jia Yi Fong, David Papadopoli, Cheryl M Koh, Laura Hulea, Manikandan Lakshmanan

Nat Commun· July 2020

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Virilizing Steroid Cell Tumor of the Ovary: Successful Surgical Management of an Enigma.
Manikandan Lakshmanan, Sameer Gupta, Vijay Kumar, Naseem Akhtar, Shiv Rajan

Indian J Surg Oncol· March 2020

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Role of serum HE4 as a prognostic marker in carcinoma of the ovary.
Manikandan Lakshmanan, Vijay Kumar, Arun Chaturvedi, Sanjeev Misra, Sameer Gupta

Indian J Cancer· January 2020

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A Role of Agrin in Maintaining the Stability of Vascular Endothelial Growth Factor Receptor-2 during Tumor Angiogenesis.
Kizito Njah, Sayan Chakraborty, Beiying Qiu, Surender Arumugam, Anandhkumar Raju, Manikandan Lakshmanan

Cell Rep· July 2019

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Germ Cell Tumor Ovary: an Institutional Experience of Treatment and Survival Outcomes.
Manikandan Lakshmanan, Sameer Gupta, Vijay Kumar, Naseem Akhtar, Arun Chaturvedi

Indian J Surg Oncol· June 2018

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Correction: Role of novel histone modifications in cancer.
Muthu K Shanmugam, Frank Arfuso, Surendar Arumugam, Arunachalam Chinnathambi, Jinsong Bian, Manikandan Lakshmanan

Oncotarget· April 2018

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