Publications by authors named "Manjunath Ghate"

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In-silico identification and exploration of small molecule coumarin-1,2,3-triazole hybrids as potential EGFR inhibitors for targeting lung cancer.
Sunil Kumar, Iqra Ali, Faheem Abbas, Faiza Shafiq, Ashok Kumar Yadav, Manjunath D Ghate

Mol Divers· December 2024

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The fusion of microfluidics and artificial intelligence: a novel alliance for medical advancements.
Priyanka A Shah, Pranav S Shrivastav, Manjunath Ghate, Vishwajit Chavda

Bioanalysis· October 2024

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Structure-guided discovery of adenosine triphosphate-competitive casein kinase 2 inhibitors.
Shivani Patel, Vivek K Vyas, Manmohan Sharma, Manjunath Ghate

Future Med Chem· June 2023

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Structure- and ligand-based drug design methods for the modeling of antimalarial agents: a review of updates from 2012 onwards.
Vivek K Vyas, Sapna Bhati, Shivani Patel, Manjunath Ghate

J Biomol Struct Dyn· December 2022

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Discovery of novel tetrahydrobenzo[b]thiophene-3-carbonitriles as histone deacetylase inhibitors.
Piyush Gediya, Vivek K Vyas, Vincenzo Carafa, Nikum Sitwala, Laura Della Torre, Manjunath D Ghate

Bioorg Chem· May 2021

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Histone deacetylase 2: A potential therapeutic target for cancer and neurodegenerative disorders.
Piyush Gediya, Palak K Parikh, Vivek K Vyas, Manjunath D Ghate

Eur J Med Chem· April 2021

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Medicinal chemistry strategies for the development of phosphodiesterase 10A (PDE10A) inhibitors - An update of recent progress.
Harsh S Amin, Palak K Parikh, Manjunath D Ghate

Eur J Med Chem· March 2021

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Medicinal Chemistry of Potassium Channel Modulators: An Update of Recent Progress (2011-2017).
Vivek K Vyas, Palak Parikh, Jonali Ramani, Manjunath Ghate

Curr Med Chem· July 2019

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Design of 2-Nitroimidazooxazine Derivatives as Deazaflavin-Dependent Nitroreductase (Ddn) Activators as Anti-Mycobacterial Agents Based on 3D QSAR, HQSAR, and Docking Study with In Silico Prediction of Activity and Toxicity.
Nirzari Gupta, Vivek K Vyas, Bhumika D Patel, Manjunath Ghate

Interdiscip Sci· June 2019

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3D QSAR-based design and liquid phase combinatorial synthesis of 1,2-disubstituted benzimidazole-5-carboxylic acid and 3-substituted-5-benzimidazo[1,2-][1,4]benzodiazepin-6(7)-one derivatives as anti-mycobacterial agents.
Nikum D Sitwala, Vivek K Vyas, Piyush Gedia, Kinjal Patel, Rania Bouzeyen, Manjunath D Ghate

Medchemcomm· May 2019

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Synthesis of 2-,4,-6-, and/or 7-substituted quinoline derivatives as human dihydroorotate dehydrogenase (hDHODH) inhibitors and anticancer agents: 3D QSAR-assisted design.
Vivek K Vyas, Gulamnizami Qureshi, Drashti Oza, Hardik Patel, Krupali Parmar, Manjunath D Ghate

Bioorg Med Chem Lett· April 2019

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Recent advances in the discovery of small molecule c-Met Kinase inhibitors.
Palak K Parikh, Manjunath D Ghate

Eur J Med Chem· January 2018

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Liquid phase combinatorial synthesis of 1,2,5-trisubstituted benzimidazole derivatives as human DHODH inhibitors.
Nikum D Sitwala, Vivek K Vyas, Bhavesh C Variya, Snehal S Patel, Chirag C Mehta, Manjunath D Ghate

Bioorg Chem· December 2017

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Molecular modeling study for the design of novel acetyl-CoA carboxylase inhibitors using 3D QSAR, molecular docking and dynamic simulations.
Vivek K Vyas, Mohini Dabasia, Gulamnizami Qureshi, Palak Patel, Manjunath Ghate

J Biomol Struct Dyn· July 2017

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Design, synthesis and anti-diabetic activity of triazolotriazine derivatives as dipeptidyl peptidase-4 (DPP-4) inhibitors.
Bhumika D Patel, Shraddha V Bhadada, Manjunath D Ghate

Bioorg Chem· June 2017

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Synthesis, anti-inflammatory, analgesic, 5-lipoxygenase (5-LOX) inhibition activities, and molecular docking study of 7-substituted coumarin derivatives.
Pavan Srivastava, Vivek K Vyas, Bhavesh Variya, Palak Patel, Gulamnizami Qureshi, Manjunath Ghate

Bioorg Chem· August 2016

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Homology modeling, binding site identification and docking study of human angiotensin II type I (Ang II-AT1) receptor.
Vivek K Vyas, Manjunath Ghate, Kinjal Patel, Gulamnizami Qureshi, Surmil Shah

Biomed Pharmacother· August 2015

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Liquid-phase combinatorial library synthesis: recent advances and future perspectives.
Kuldipsinh P Barot, Stoyanka Nikolova, Illiyan Ivanov, Manjunath D Ghate

Comb Chem High Throughput Screen· April 2015

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Ligand and structure-based approaches for the identification of SIRT1 activators.
Vivek K Vyas, Ashutosh Goel, Manjunath Ghate, Palak Patel

Chem Biol Interact· February 2015

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Design, synthesis and docking studies of some novel (R)-2-(4'-chlorophenyl)-3-(4'-nitrophenyl)-1,2,3,5-tetrahydrobenzo[4,5] imidazo [1,2-c]pyrimidin-4-ol derivatives as antitubercular agents.
Kuldipsinh P Barot, Shailesh V Jain, Nirzari Gupta, Laurent Kremer, Shubhra Singh, Manjunath D Ghate

Eur J Med Chem· August 2014

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Design, synthesis and pharmacological evaluation of novel substituted quinoline-2-carboxamide derivatives as human dihydroorotate dehydrogenase (hDHODH) inhibitors and anticancer agents.
Vivek K Vyas, Bhavesh Variya, Manjunath D Ghate

Eur J Med Chem· July 2014

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Recent approaches to medicinal chemistry and therapeutic potential of dipeptidyl peptidase-4 (DPP-4) inhibitors.
Bhumika D Patel, Manjunath D Ghate

Eur J Med Chem· March 2014

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Antitubercular drug development: current status and research strategies.
Kuldipsinh P Barot, Stoyanka Nikolova, Illiyan Ivanov, Manjunath D Ghate

Mini Rev Med Chem· October 2013

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Benzopyran derivatives as cardio-selective ATP-sensitive potassium channel openers: a review.
Mohsina Bano, Kuldipsinh P Barot, Shaik Miftah Ahmed, Stoyanka Nikolova, Illiyan Ivanov, Manjunath D Ghate

Mini Rev Med Chem· October 2013

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3D QSAR studies on substituted benzimidazole derivatives as angiotensin II-AT1 receptor antagonist.
Vivek K Vyas, Manjunath Ghate, Chetan Chintha, Paresh Patel

Curr Comput Aided Drug Des· September 2013

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