Publications by authors named "Manlio Ferrarini"

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Chronic lymphocytic leukemia often arises by a multiclonal selection process.
Davide Bagnara, Andrea N Mazzarello, Niccolò Cardente, Stefano Vergani, Siddha Kasar, Manlio Ferrarini

Haematologica· August 2025

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MicroRNA Profiling as a Predictive Indicator for Time to First Treatment in Chronic Lymphocytic Leukemia: Insights from the O-CLL1 Prospective Study.
Ennio Nano, Francesco Reggiani, Adriana Agnese Amaro, Paola Monti, Monica Colombo, Manlio Ferrarini

Noncoding RNA· August 2024

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Genes selection using deep learning and explainable artificial intelligence for chronic lymphocytic leukemia predicting the need and time to therapy.
Fortunato Morabito, Carlo Adornetto, Paola Monti, Adriana Amaro, Francesco Reggiani, Manlio Ferrarini

Front Oncol· August 2023

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The time to first treatment is an independent predictor of overall survival in chronic lymphocytic leukemia.
Fortunato Morabito, Giovanni Tripepi, Francesca Romana Mauro, Luca Laurenti, Gianluigi Reda, Manlio Ferrarini

Am J Hematol· July 2023

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Editorial: Role of the antigen receptor in the pathogenesis of B-cell lymphoid malignancies.
Andreas Agathangelidis, Manlio Ferrarini, Franco Fais

Front Oncol· March 2023

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The spectrum of subclonal TP53 mutations in chronic lymphocytic leukemia: A next generation sequencing retrospective study.
Giuseppa De Luca, Giannamaria Cerruti, Sonia Lastraioli, Romana Conte, Adalberto Ibatici, Manlio Ferrarini

Hematol Oncol· December 2022

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A High Percentage of CD16+ Monocytes Correlates with the Extent of Bone Erosion in Chronic Lymphocytic Leukemia Patients: The Impact of Leukemic B Cells in Monocyte Differentiation and Osteoclast Maturation.
Paolo Giannoni, Cecilia Marini, Giovanna Cutrona, Katia Todoerti, Antonino Neri, Manlio Ferrarini

Cancers (Basel)· December 2022

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Old and New Facts and Speculations on the Role of the B Cell Receptor in the Origin of Chronic Lymphocytic Leukemia.
Davide Bagnara, Andrea Nicola Mazzarello, Fabio Ghiotto, Monica Colombo, Giovanna Cutrona, Manlio Ferrarini

Int J Mol Sci· November 2022

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MiR-146b-5p regulates IL-23 receptor complex expression in chronic lymphocytic leukemia cells.
Serena Matis, Anna Grazia Recchia, Monica Colombo, Martina Cardillo, Marina Fabbi, Manlio Ferrarini

Blood Adv· October 2022

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Characterizing Features of Human Circulating B Cells Carrying CLL-Like Stereotyped Immunoglobulin Rearrangements.
Davide Bagnara, Monica Colombo, Daniele Reverberi, Serena Matis, Rosanna Massara, Manlio Ferrarini

Front Oncol· June 2022

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Chronic lymphocytic leukemia cells impair osteoblastogenesis and promote osteoclastogenesis: role of TNFα, IL-6 and IL-11 cytokines.
Paolo Giannoni, Cecilia Marini, Giovanna Cutrona, Serena Matis, Maria Cristina Capra, Manlio Ferrarini

Haematologica· October 2021

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Effectiveness of ibrutinib as first-line therapy for chronic lymphocytic leukemia patients and indirect comparison with rituximab-bendamustine: Results of study on 486 cases outside clinical trials.
Fortunato Morabito, Giovanni Tripepi, Giovanni Del Poeta, Francesca Romana Mauro, Gianluigi Reda, Manlio Ferrarini

Am J Hematol· August 2021

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TP53 disruption as a risk factor in the era of targeted therapies: A multicenter retrospective study of 525 chronic lymphocytic leukemia cases.
Fortunato Morabito, Giovanni Del Poeta, Francesca Romana Mauro, Gianluigi Reda, Paolo Sportoletti, Manlio Ferrarini

Am J Hematol· August 2021

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Lymphocyte Doubling Time As A Key Prognostic Factor To Predict Time To First Treatment In Early-Stage Chronic Lymphocytic Leukemia.
Fortunato Morabito, Giovanni Tripepi, Riccardo Moia, Anna Grazia Recchia, Paola Boggione, Manlio Ferrarini

Front Oncol· August 2021

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Validation of the Alternative International Prognostic Score-E (AIPS-E): Analysis of Binet stage A chronic lymphocytic leukemia patients enrolled into the O-CLL1-GISL protocol.
Fortunato Morabito, Giovanni Tripepi, Ernesto Vigna, Sabrina Bossio, Graziella D'Arrigo, Manlio Ferrarini

Eur J Haematol· June 2021

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Assessment of the 4-factor score: Retrospective analysis of 586 CLL patients receiving ibrutinib. A campus CLL study.
Fortunato Morabito, Giovanni Tripepi, Giovanni Del Poeta, Francesca Romana Mauro, Gianluigi Reda, Manlio Ferrarini

Am J Hematol· May 2021

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Comparison of ibrutinib and idelalisib plus rituximab in real-life relapsed/resistant chronic lymphocytic leukemia cases.
Fortunato Morabito, Giovanni Tripepi, Giovanni Del Poeta, Francesca Romana Mauro, Gianluigi Reda, Manlio Ferrarini

Eur J Haematol· April 2021

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Human pluripotent stem cells identify molecular targets of trisomy 12 in chronic lymphocytic leukemia patients.
Jennifer C Reid, Diana Golubeva, Allison L Boyd, Cameron G Hollands, Charisa Henly, Manlio Ferrarini

Cell Rep· March 2021

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Antitumor Effects of PRIMA-1 and PRIMA-1 (APR246) in Hematological Malignancies: Still a Mutant P53-Dependent Affair?
Paola Menichini, Paola Monti, Andrea Speciale, Giovanna Cutrona, Serena Matis, Manlio Ferrarini

Cells· January 2021

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Time to first treatment and P53 dysfunction in chronic lymphocytic leukaemia: results of the O-CLL1 study in early stage patients.
Paola Monti, Marta Lionetti, Giuseppa De Luca, Paola Menichini, Anna Grazia Recchia, Manlio Ferrarini

Sci Rep· October 2020

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Heterogeneity of Mutations and P53 Protein Residual Function in Cancer: Does It Matter?
Paola Monti, Paola Menichini, Andrea Speciale, Giovanna Cutrona, Franco Fais, Manlio Ferrarini

Front Oncol· October 2020

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Validation of a survival-risk score (SRS) in relapsed/refractory CLL patients treated with idelalisib-rituximab.
Massimo Gentile, Enrica Antonia Martino, Andrea Visentin, Marta Coscia, Gianluigi Reda, Manlio Ferrarini

Blood Cancer J· September 2020

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TP53 dysfunction in chronic lymphocytic leukemia: clinical relevance in the era of B-cell receptors and BCL-2 inhibitors.
Fortunato Morabito, Massimo Gentile, Paola Monti, Anna Grazia Recchia, Paola Menichini, Manlio Ferrarini

Expert Opin Investig Drugs· August 2020

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Optimization of a WGA-Free Molecular Tagging-Based NGS Protocol for CTCs Mutational Profiling.
Giuseppa De Luca, Barbara Cardinali, Lucia Del Mastro, Sonia Lastraioli, Franca Carli, Manlio Ferrarini

Int J Mol Sci· June 2020

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International prognostic score for asymptomatic early-stage chronic lymphocytic leukemia.
Adalgisa Condoluci, Lodovico Terzi di Bergamo, Petra Langerbeins, Manuela A Hoechstetter, Carmen D Herling, Manlio Ferrarini

Blood· May 2020

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