Publications by authors named "Mann-Jen Hour"

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Design and Synthesis of Holu-7, a Quinazolinone Derivative With an Active Stereo Geometry and Polar 2,4-Dihydroxyphenyl Group, as a Selective Anticancer Agent.
Kuo-Chu Lai, Hui-Hsia Hsieh, Yi-Liang Lu, Shin-Yi Liu, Hai-Anh Ha, Mann-Jen Hour

Chem Biol Drug Des· December 2025

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Effect of antihypertensive drugs on survival in patients with non-small cell lung cancer on epidermal growth factor receptor inhibitors.
Hui-Hsia Hsieh, Tien-Yuan Wu, Wan-Yi Lee, Chi-Hua Chen, Yu-Hung Kuo, Mann-Jen Hour

Am J Cancer Res· November 2025

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Assessing the inhibitory effects of some secondary amines, thioureas and 1,3-dimethyluracil conjugates of (-)-cytisine and thermopsine on the RNA-dependent RNA polymerase of SARS-CoV-1 and SARS-CoV-2.
Yeh Chen, Mann-Jen Hour, Chen-Sheng Lin, Young-Sheng Chang, Zan-Yu Chen

Bioorg Med Chem Lett· November 2024

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Efficacy of HMJ-38, a new quinazolinone analogue, against the gemcitabine-resistant MIA-PaCa-2 pancreatic cancer cells.
Mann-Jen Hour, Fuu-Jen Tsai, I-Lu Lai, Je-Wei Tsao, Jo-Hua Chiang

Biomedicine (Taipei)· December 2023

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Survival Outcomes of Calcium Channel Blocker Therapy in Patients With Non-Small Cell Lung Cancer Treated With Epidermal Growth Factor Receptor Inhibitors: A Retrospective Study.
Hui-Hsia Hsieh, Tien-Yuan Wu, Chi-Hua Chen, Yu-Hung Kuo, Mann-Jen Hour

Integr Cancer Ther· June 2023

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Survival outcomes of beta-blocker usage in HER2-positive advanced breast cancer patients: a retrospective cohort study.
Hui-Hsia Hsieh, Tien-Yuan Wu, Chi-Hua Chen, Yu-Hung Kuo, Mann-Jen Hour

Ther Adv Drug Saf· June 2023

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Clinical impact of tetracyclines and/or proton pump inhibitors on the efficacy of epidermal growth factor receptor inhibitors in non-small cell lung cancer: a retrospective cohort study.
Hui-Hsia Hsieh, Tien-Yuan Wu, Chi-Hua Chen, Yu-Hung Kuo, Mann-Jen Hour

BMC Cancer· February 2023

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Glycyrrhizic Acid Derivatives Bearing Amino Acid Residues in the Carbohydrate Part as Dengue Virus E Protein Inhibitors: Synthesis and Antiviral Activity.
Mann-Jen Hour, Yeh Chen, Chen-Sheng Lin, Lidia A Baltina, Ju-Ying Kan

Int J Mol Sci· September 2022

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Cost-effectiveness and clinical outcomes of intermittent/continuous proton pump inhibitors infusion in high bleeding risk of ulcers: A retrospective observational cohort study.
Hui-Hsia Hsieh, Tien-Yuan Wu, Chi-Hua Chen, Mann-Jen Hour

Medicine (Baltimore)· December 2021

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Glycyrrhetinic acid derivatives as Zika virus inhibitors: Synthesis and antiviral activity in vitro.
Lidia A Baltina, Hsueh-Chou Lai, Ya-Chi Liu, Su-Hua Huang, Mann-Jen Hour

Bioorg Med Chem· July 2021

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Establishment of a Novel Temozolomide Resistant Subline of Glioblastoma Multiforme Cells and Comparative Transcriptome Analysis With Parental Cells.
Hai-Anh Ha, Jai-Sing Yang, Fuu-Jen Tsai, Chang-Wei Li, Yih-Dih Cheng, Mann-Jen Hour

Anticancer Res· May 2021

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Antiviral activity of glycyrrhizic acid conjugates with amino acid esters against Zika virus.
Lidia A Baltina, Mann-Jen Hour, Ya-Chi Liu, Young-Sheng Chang, Su-Hua Huang

Virus Res· March 2021

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Analysis of COVID-19 prevention and treatment in Taiwan.
Yu-Jen Chiu, Jo-Hua Chiang, Chih-Wei Fu, Mann-Jen Hour, Hai-Anh Ha

Biomedicine (Taipei)· March 2021

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Novel quinazolinone MJ‑33 induces AKT/mTOR‑mediated autophagy‑associated apoptosis in 5FU‑resistant colorectal cancer cells.
Hai-Anh Ha, Jo-Hua Chiang, Fuu-Jen Tsai, Da-Tian Bau, Yu-Ning Juan, Mann-Jen Hour

Oncol Rep· February 2021

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Antitumor Effects of the Novel Quinazolinone Holu-12: Induction of Mitotic Arrest and Apoptosis in Human Oral Squamous Cell Carcinoma CAL27 Cells.
Kuo-Chu Lai, Yi-Ting Chia, Ling-Huei Yih, Yi-Liang Lu, Shih-Ting Chang, Mann-Jen Hour

Anticancer Res· January 2021

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Quercetin depletes intracellular Ca stores and blunts ATP-triggered Ca signaling in bEnd.3 endothelial cells.
Cing-Yu Chen, Mann-Jen Hour, Lian-Ru Shiao, Kar-Lok Wong, Yuk-Man Leung

Fundam Clin Pharmacol· April 2020

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Antagonism of Ca-sensing receptors by NPS 2143 is transiently masked by p38 activation in mouse brain bEND.3 endothelial cells.
Cing-Yu Chen, Mann-Jen Hour, Wen-Chuan Lin, Kar-Lok Wong, Lian-Ru Shiao

Naunyn Schmiedebergs Arch Pharmacol· July 2019

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Fenofibrate induces human hepatoma Hep3B cells apoptosis and necroptosis through inhibition of thioesterase domain of fatty acid synthase.
Bang-Jau You, Mann-Jen Hour, Li-Yun Chen, Shu-Ching Luo, Po-Hsiang Hsu

Sci Rep· March 2019

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hydroxycinnamoyl Ursolic Acid Induced ROS-Dependent p53-Mediated Mitochondrial Apoptosis in Oral Cancer Cells.
Ching-Ying Wang, Chen-Sheng Lin, Chun-Hung Hua, Yu-Jen Jou, Chi-Ren Liao, Mann-Jen Hour

Biomol Ther (Seoul)· January 2019

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Epigallocatechin-3-gallate inhibits the early stages of Japanese encephalitis virus infection.
Ching-Ying Wang, Mann-Jen Hour, Hsueh-Chou Lai, Chao-Hsien Chen, Pei-Jung Chang

Virus Res· July 2018

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Disruption of IGF‑1R signaling by a novel quinazoline derivative, HMJ‑30, inhibits invasiveness and reverses epithelial-mesenchymal transition in osteosarcoma U‑2 OS cells.
Yu-Jen Chiu, Mann-Jen Hour, Yi-An Jin, Chi-Cheng Lu, Fuu-Jen Tsai

Int J Oncol· May 2018

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SARS coronavirus papain-like protease up-regulates the collagen expression through non-Samd TGF-β1 signaling.
Ching-Ying Wang, Chien-Yi Lu, Shih-Wen Li, Chien-Chen Lai, Chun-Hung Hua, Mann-Jen Hour

Virus Res· May 2017

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Tubacin, an HDAC6 Selective Inhibitor, Reduces the Replication of the Japanese Encephalitis Virus via the Decrease of Viral RNA Synthesis.
Chien-Yi Lu, Yi-Chih Chang, Chun-Hung Hua, Chieh Chuang, Su-Hua Huang, Mann-Jen Hour

Int J Mol Sci· May 2017

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Single-Round Infectious Particle Antiviral Screening Assays for the Japanese Encephalitis Virus.
Chien-Yi Lu, Mann-Jen Hour, Ching-Ying Wang, Su-Hua Huang, Wen-Xiang Mu

Viruses· April 2017

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Antiviral Potential of a Novel Compound CW-33 against Enterovirus A71 via Inhibition of Viral 2A Protease.
Ching-Ying Wang, An-Cheng Huang, Mann-Jen Hour, Su-Hua Huang, Szu-Hao Kung

Viruses· June 2015

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