Publications by authors named "Mannkyu Hong"

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Scalable Thiol Reactivity Profiling Identifies Azetidinyl Oxadiazoles as Cysteine-Targeting Electrophiles.
Fereshte Ghorbani, Shaochen You, Gennadii A Grabovyi, Mannkyu Hong, Garrett Lindsey

J Am Chem Soc· November 2024

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Discovery of N-(1-(2-hydroxyethyl)quinolin-2-one)-N'-(1-phenyl-1H-pyrazol-5-yl)methyl) urea as Mode-Selective TRPV1 antagonist.
Dongxu Zuo, Mannkyu Hong, Aeran Jung, Sunho Lee, Nayeon Do, Hongryul Yoon

Bioorg Med Chem Lett· March 2024

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Designing multi-target-directed flavonoids: a strategic approach to Alzheimer's disease.
Seongmin Park, Mingeun Kim, Yuxi Lin, Mannkyu Hong, Geewoo Nam

Chem Sci· September 2023

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S-lactoyl modification of KEAP1 by a reactive glycolytic metabolite activates NRF2 signaling.
Yeonjin Ko, Mannkyu Hong, Seungbeom Lee, Manoj Kumar, Lara Ibrahim

Proc Natl Acad Sci U S A· May 2023

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Unveiling the impact of oxidation-driven endogenous protein interactions on the dynamics of amyloid-β aggregation and toxicity.
Zhi Du, Eunju Nam, Yuxi Lin, Mannkyu Hong, Tamás Molnár

Chem Sci· May 2023

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Excited-State Intramolecular Hydrogen Transfer of Compact Molecules Controls Amyloid Aggregation Profiles.
Mannkyu Hong, Mingeun Kim, Jiwon Yoon, Seung-Hee Lee, Mu-Hyun Baik

JACS Au· September 2022

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Understanding the mechanism of direct visible-light-activated [2 + 2] cycloadditions mediated by Rh and Ir photocatalysts: combined computational and spectroscopic studies.
Hoimin Jung, Mannkyu Hong, Marianna Marchini, Marco Villa, Philipp S Steinlandt

Chem Sci· July 2021

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Multiple reactivities of flavonoids towards pathological elements in Alzheimer's disease: structure-activity relationship.
Geewoo Nam, Mannkyu Hong, Juri Lee, Hyuck Jin Lee, Yonghwan Ji

Chem Sci· September 2020

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Design and Optimization of Catalysts Based on Mechanistic Insights Derived from Quantum Chemical Reaction Modeling.
Seihwan Ahn, Mannkyu Hong, Mahesh Sundararajan, Daniel H Ess, Mu-Hyun Baik

Chem Rev· June 2019

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Investigation of B,C-ring truncated deguelin derivatives as heat shock protein 90 (HSP90) inhibitors for use as anti-breast cancer agents.
Ho Shin Kim, Van-Hai Hoang, Mannkyu Hong, Kyung Chul Kim, Jihyae Ann, Jae Hong Seo

Bioorg Med Chem· April 2019

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Scorpionate Catalysts for Coupling CO and Epoxides to Cyclic Carbonates: A Rational Design Approach for Organocatalysts.
Mannkyu Hong, Yoseph Kim, Hyejin Kim, Hee Jin Cho, Mu-Hyun Baik

J Org Chem· August 2018

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Understanding the Origin of the Regioselectivity in Cyclopolymerizations of Diynes and How to Completely Switch It.
Hoimin Jung, Kijung Jung, Mannkyu Hong, Seongyeon Kwon, Kunsoon Kim, Soon Hyeok Hong

J Am Chem Soc· January 2018

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Mechanistic Investigation of Bis(imino)pyridine Manganese Catalyzed Carbonyl and Carboxylate Hydrosilylation.
Tufan K Mukhopadhyay, Christopher L Rock, Mannkyu Hong, Daniel C Ashley, Thomas L Groy

J Am Chem Soc· April 2017

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Synthesis and biological evaluation of C-ring truncated deguelin derivatives as heat shock protein 90 (HSP90) inhibitors.
Ho Shin Kim, Mannkyu Hong, Jihyae Ann, Suyoung Yoon, Cong-Truong Nguyen

Bioorg Med Chem· November 2016

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Ring-truncated deguelin derivatives as potent Hypoxia Inducible Factor-1α (HIF-1α) inhibitors.
Ho Shin Kim, Mannkyu Hong, Su-Chan Lee, Ho-Young Lee, Young-Ger Suh

Eur J Med Chem· November 2015

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α-Substituted 2-(3-fluoro-4-methylsulfonamidophenyl)acetamides as potent TRPV1 antagonists.
Phuong-Thao Tran, Ho Shin Kim, Jihyae Ann, Sung-Eun Kim, Changhoon Kim, Mannkyu Hong, Sunhye Hong

Bioorg Med Chem Lett· June 2015

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Pyridine C-region analogs of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as potent TRPV1 antagonists.
HyungChul Ryu, Sejin Seo, Jee-Young Lee, Tae-Hwan Ha, Sunho Lee, Mannkyu Hong

Eur J Med Chem· March 2015

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