Publications by authors named "Manoharan Ravi"

Claim this Profile
E
Enhanced Cytotoxicity of Half-Sandwich Ruthenium(II) Complex Containing -Substituted Salicyllimidazo[1,5-]pyridine toward Hormone-Independent Triple-Negative Breast Cancer Cells.
Ibanpynhunlang Passi, Liji Muthirakalayil Abraham, Acily Skadon Worral Wilfred Raj, Manikandan Varadhan, Surya Muthuraman, Ravi Manoharan

Inorg Chem· July 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
NUAKs facilitate mTOR-mediated NSCLC proliferation and metastasis by modulating glucose metabolism and inhibiting p53 activity.
Jaithanya Yesupogu Moorthy Babu, Ravi Manoharan

Biochim Biophys Acta Mol Cell Res· March 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
NUAKs promote mTOR/c-Myc-induced glucose and glutamine reprogramming for cell growth and metastasis in breast cancer cells.
Acily Skadon Worral Wilfred Raj, Ravi Manoharan

Biochim Biophys Acta Mol Basis Dis· January 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Salt-inducible kinases (SIKs) in cancer: mechanisms of action and therapeutic prospects.
Ravi Manoharan

Drug Discov Today· January 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Task-sharing spinal anaesthesia care in three rural Indian hospitals: a non-inferiority randomised controlled clinical trial.
Nandakumar Menon, Regi George, Raman Kataria, Ravi Manoharan, Meredith B Brooks

BMJ Glob Health· August 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Organosulfur Compound Identified from Striga angustifolia (D. Don) C.J. Saldanha Inhibits Lung Cancer Growth and Induces Apoptosis via p53/mTOR Signaling Pathway.
Kannan Raja, Arumugam Vignesh, Ponnusamy Lavanya, Manoharan Ravi, Subramaniam Selvakumar

Appl Biochem Biotechnol· December 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
MARK2/4 promotes Warburg effect and cell growth in non-small cell lung carcinoma through the AMPKα1/mTOR/HIF-1α signaling pathway.
Sathan Raj Natarajan, Lavanya Ponnusamy, Ravi Manoharan

Biochim Biophys Acta Mol Cell Res· July 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
MARK2 potentiate aerobic glycolysis-mediated cell growth in breast cancer through regulating mTOR/HIF-1α and p53 pathways.
Lavanya Ponnusamy, Sathan Raj Natarajan, Ravi Manoharan

J Cell Biochem· April 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
DAXX ameliorates metabolic dysfunction in mice with diet-induced obesity by activating the AMP-activated protein kinase-related kinase MPK38/MELK.
Hyun-A Seong, Ravi Manoharan, Hyunjung Ha

Biochem Biophys Res Commun· October 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Distinctive role of SIK1 and SIK3 isoforms in aerobic glycolysis and cell growth of breast cancer through the regulation of p53 and mTOR signaling pathways.
Lavanya Ponnusamy, Ravi Manoharan

Biochim Biophys Acta Mol Cell Res· April 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
MELK/MPK38 in cancer: from mechanistic aspects to therapeutic strategies.
Karthik Thangaraj, Lavanya Ponnusamy, Sathan Raj Natarajan, Ravi Manoharan

Drug Discov Today· December 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Berberine and Emodin abrogates breast cancer growth and facilitates apoptosis through inactivation of SIK3-induced mTOR and Akt signaling pathway.
Lavanya Ponnusamy, Gugan Kothandan, Ravi Manoharan

Biochim Biophys Acta Mol Basis Dis· November 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
U
Understanding the dual mechanism of bioactive peptides targeting the enzymes involved in Renin Angiotensin System (RAS): An approach.
Seshan Gunalan, Kanagasabai Somarathinam, Jayanti Bhattacharya, Shantkriti Srinivasan, S M Jaimohan, Ravi Manoharan

J Biomol Struct Dyn· October 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Therapeutic aspects of AMPK in breast cancer: Progress, challenges, and future directions.
Lavanya Ponnusamy, Sathan Raj Natarajan, Karthik Thangaraj, Ravi Manoharan

Biochim Biophys Acta Rev Cancer· August 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Dual Roles of Serine-Threonine Kinase Receptor-Associated Protein (STRAP) in Redox-Sensitive Signaling Pathways Related to Cancer Development.
Ravi Manoharan, Hyun-A Seong, Hyunjung Ha

Oxid Med Cell Longev· October 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Smad proteins differentially regulate obesity-induced glucose and lipid abnormalities and inflammation via class-specific control of AMPK-related kinase MPK38/MELK activity.
Hyun-A Seong, Ravi Manoharan, Hyunjung Ha

Cell Death Dis· May 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
Z
Zinc finger protein ZPR9 functions as an activator of AMPK-related serine/threonine kinase MPK38/MELK involved in ASK1/TGF-β/p53 signaling pathways.
Hyun-A Seong, Ravi Manoharan, Hyunjung Ha

Sci Rep· February 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Coordinate Activation of Redox-Dependent ASK1/TGF-β Signaling by a Multiprotein Complex (MPK38, ASK1, SMADs, ZPR9, and TRX) Improves Glucose and Lipid Metabolism in Mice.
Hyun-A Seong, Ravi Manoharan, Hyunjung Ha

Antioxid Redox Signal· March 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A crucial role for the phosphorylation of STRAP at Ser(188) by MPK38 in STRAP-dependent cell death through ASK1, TGF-β, p53, and PI3K/PDK1 signaling pathways.
Hyun-A Seong, Ravi Manoharan, Hyunjung Ha

Cell Cycle· July 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Thioredoxin inhibits MPK38-induced ASK1, TGF-β, and p53 function in a phosphorylation-dependent manner.
Ravi Manoharan, Hyun-A Seong, Hyunjung Ha

Free Radic Biol Med· October 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
PDK1 protein phosphorylation at Thr354 by murine protein serine-threonine kinase 38 contributes to negative regulation of PDK1 protein activity.
Hyun-A Seong, Haiyoung Jung, Ravi Manoharan, Hyunjung Ha

J Biol Chem· June 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Positive regulation of apoptosis signal-regulating kinase 1 signaling by ZPR9 protein, a zinc finger protein.
Hyun-A Seong, Haiyoung Jung, Ravi Manoharan, Hyunjung Ha

J Biol Chem· September 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
B-MYB positively regulates serine-threonine kinase receptor-associated protein (STRAP) activity through direct interaction.
Hyun-A Seong, Ravi Manoharan, Hyunjung Ha

J Biol Chem· March 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Serine-threonine kinase receptor-associated protein inhibits apoptosis signal-regulating kinase 1 function through direct interaction.
Haiyoung Jung, Hyun-A Seong, Ravi Manoharan, Hyunjung Ha

J Biol Chem· January 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis