Publications by authors named "Manojit Pal"

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Towards next-generation 5-hydroxytryptamine 2C receptor modulators: Greener synthesis and evaluation of novel isocoumarin derivatives as PAAMs of 5-HTR.
Kaushik Sarkar, Deepesh Biswas, B Yogi Sreenivas, Rapaka Naimisha, Navneet Bung, Manojit Pal

Bioorg Chem· November 2025

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Early preclinical development of amino acid biosynthesis pathway inhibitor DRILS-1398 as a potential anti-TB drug.
Deepesh Biswas, Rebecca Kristina Edwin, K Shiva Kumar, Anwar Alam, Dhiraj Kumar, Gopalakrishnan Bulusu, Manojit Pal

iScience· June 2025

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Organic Chemistry-Biology interface research activities in India.
Rambabu Dandela, Manojit Pal

Bioorg Chem· January 2025

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Targeting next-generation PDE4 inhibitors in search of potential management of rheumatoid arthritis and psoriasis.
Harshavardhan Bhuktar, B Thirupataiah, Guntipally Mounika, Snigdha Samarpita, Arulkumaran Rithvik, Manojit Pal

Bioorg Chem· October 2024

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Design, synthesis and evaluation of 2-aryl quinoline derivatives against 12R-lipoxygenase (12R-LOX): Discovery of first inhibitor of 12R-LOX.
Harshavardhan Bhuktar, Sharda Shukla, Kumar Reddy Kakularam, Srikanth Battu, Manupati Srikanth, Pallu Reddanna, Manojit Pal

Bioorg Chem· September 2023

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Ultrasound assisted Cu-catalyzed Ullmann-Goldberg type coupling-cyclization in a single pot: Synthesis and evaluation of 11-pyrido[2,1-]quinazolin-11-ones against SARS-CoV-2 RdRp.
Matta Manikanttha, Kolli Deepti, Mandava Bhuvan Tej, Mandava Bhagya Tej, A Gopi Reddy, Manojit Pal

J Mol Struct· May 2023

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Wang resin catalysed sonochemical synthesis of pyrazolo[4,3-d]pyrimidinones and 2,3-dihydroquinazolin-4(1H)-ones: Identification of chorismate mutase inhibitors having effects on Mycobacterium tuberculosis cell viability.
Sharda Shukla, R Nishanth Rao, Harshavardhan Bhuktar, Rebecca Kristina Edwin, Trinath Jamma, Manojit Pal

Bioorg Chem· May 2023

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Synthesis and characterization of two known and one new impurities of dolutegravir: evaluation of certain intermediates against SARS CoV-2 O-ribose methyltransferase (OMTase).
Sailaja Garrepalli, Ramesh Gudipati, Ravikumar Kapavarapu, Kunta Ravindhranath, Manojit Pal

J Mol Struct· January 2023

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De novo design of anti-tuberculosis agents using a structure-based deep learning method.
Sowmya Ramaswamy Krishnan, Navneet Bung, Siladitya Padhi, Gopalakrishnan Bulusu, Parimal Misra, Manojit Pal, Rajgopal Srinivasan

J Mol Graph Model· January 2023

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Sonochemical synthesis and biological evaluation of isoquinolin-1(2H)-one/isoindolin-1-one derivatives: Discovery of a positive ago-allosteric modulator (PAAM) of 5HTR.
Jetta Sandeep Kumar, Rapaka Naimisha, B Thirupataiah, Gangireddy Sujeevan Reddy, Navneet Bung, Gopalakrishnan Bulusu, Manojit Pal

Bioorg Chem· December 2022

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Recent advances in transition metal-catalyzed reactions of chloroquinoxalines: Applications in bioorganic chemistry.
Gangireddy Sujeevan Reddy, Jetta Sandeep Kumar, B Thirupataiah, Harshavardhan Bhuktar, Sharda Shukla, Manojit Pal

Bioorg Chem· December 2022

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Pd/Cu-catalyzed access to novel 3-(benzofuran-2-ylmethyl) substituted (pyrazolo/benzo)triazinone derivatives: their / evaluation as inhibitors of chorismate mutase (CM).
Gangireddy Sujeevan Reddy, Sharda Shukla, Harshavardhan Bhuktar, Kazi Amirul Hossain, Rebecca Kristina Edwin, Manojit Pal

RSC Adv· September 2022

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Ultrasound assisted one-pot synthesis of rosuvastatin based novel azaindole derivatives via coupling-cyclization strategy under Pd/Cu-catalysis: Their evaluation as potential cytotoxic agents.
Jetta Sandeep Kumar, Gangireddy Sujeevan Reddy, Raghavender Medishetti, Kazi Amirul Hossain, B Thirupataiah, Manojit Pal

Bioorg Chem· July 2022

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Fe(III)-catalyzed regioselective and faster synthesis of isocoumarins with 3-oxoalkyl moiety at C-4: Identification of new inhibitors of PDE4.
B Thirupataiah, Harshavardhan Bhuktar, Guntipally Mounika, Gangireddy Sujeevan Reddy, Jetta Sandeep Kumar, Manojit Pal

Bioorg Chem· April 2022

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Amberlyst-15 catalysed synthesis of novel indole derivatives under ultrasound irradiation: Their evaluation as serotonin 5-HT receptor agonists.
Gangireddy Sujeevan Reddy, Rajamanikkam Kamaraj, Kazi Amirul Hossain, Jetta Sandeep Kumar, B Thirupataiah, Manojit Pal

Bioorg Chem· November 2021

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PdCl-catalyzed synthesis of a new class of isocoumarin derivatives containing aminosulfonyl / aminocarboxamide moiety: First identification of a isocoumarin based PDE4 inhibitor.
B Thirupataiah, Guntipally Mounika, Gangireddy Sujeevan Reddy, Jetta Sandeep Kumar, Kazi Amirul Hossain, Manojit Pal

Eur J Med Chem· October 2021

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CuCl-catalyzed inexpensive, faster and ligand/additive free synthesis of isoquinolin-1(2H)-one derivatives via the coupling-cyclization strategy: Evaluation of a new class of compounds as potential PDE4 inhibitors.
B Thirupataiah, Guntipally Mounika, Gangireddy Sujeevan Reddy, Jetta Sandeep Kumar, Ravikumar Kapavarapu, Manojit Pal

Bioorg Chem· October 2021

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Pd-catalysed general access to 7-membered N/O-heterocyclic compounds as potential agents against inflammation.
B Thirupataiah, Gangireddy Sujeevan Reddy, Guntipally Mounika, Jetta Sandeep Kumar, Kazi Amirul Hossain, Manojit Pal

Chem Commun (Camb)· September 2021

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Indole Derivatives as Anti-Tubercular Agents: An Overview on their Synthesis and Biological Activities.
Gangireddy Sujeevan Reddy, Manojit Pal

Curr Med Chem· August 2021

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Lemon Juice as a Biocatalyst Under Ultrasound Irradiation: Synthesis and Pharmacological Evaluation of 2-amino 1,3,4-thiadiazoles.
Malavattu G Prasad, Chapala V Lakshmi, Naresh K Katari, Manojit Pal

Anticancer Agents Med Chem· May 2021

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assessment and sonochemical synthesis of 2-alkynyl 3-chloropyrazines as prospective ligands for SARS-CoV-2.
M V Satyanarayana, Alugubelli Gopi Reddy, M Yedukondalu, Mandava Bhuvan Tej, Kazi Amirul Hossain, Manojit Pal

J Mol Struct· May 2021

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Pyrrolo[2,3]quinoxalines in attenuating cytokine storm in COVID-19: their sonochemical synthesis and / assessment.
Raviteja Chemboli, Ravikumar Kapavarapu, K Deepti, K R S Prasad, Alugubelli Gopi Reddy, Manojit Pal

J Mol Struct· April 2021

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Ultrasound assisted synthesis of 3-alkynyl substituted 2-chloroquinoxaline derivatives: Their assessment as potential ligands for N-protein of SARS-CoV-2.
Shaik Shahinshavali, Kazi Amirul Hossain, Abbaraju Venkata Durga Nagendra Kumar, Alugubelli Gopi Reddy, Deepti Kolli, Manojit Pal

Tetrahedron Lett· October 2020

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Rosuvastatin based novel 3-substituted isocoumarins / 3-alkylidenephthalides: Ultrasound assisted synthesis and identification of new anticancer agents.
Jetta Sandeep Kumar, B Thirupataiah, Raghavender Medishetti, Aramita Ray, Shilpak Dilip Bele, Manojit Pal

Eur J Med Chem· September 2020

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Ultrasound assisted rapid synthesis of mefenamic acid based indole derivatives under ligand free Cu-catalysis: Their pharmacological evaluation.
Rapolu Venkateshwarlu, Shambhu Nath Singh, Vidavalur Siddaiah, Hindupur Ramamohan, Rambabu Dandela, Manojit Pal

Bioorg Med Chem Lett· May 2020

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