Publications by authors named "Manolis Kellis"

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Gamma entrainment using audiovisual stimuli alleviates chemobrain pathology and cognitive impairment induced by chemotherapy in mice.
TaeHyun Kim, Benjamin T James, Martin C Kahn, Cristina Blanco-Duque, Fatema Abdurrob, Md Rezaul Islam, Nicolas S Lavoie, Manolis Kellis, Li-Huei Tsai

Sci Transl Med· March 2024

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New approaches for understanding the potential role of microbes in Alzheimer's disease.
Heather E Whitson, William A Banks, Monica M Diaz, Bess Frost, Manolis Kellis, Richard Lathe, Kenneth E Schmader, Serena S Spudich, Rudolph Tanzi, Gwenn Garden

Brain Behav Immun Health· March 2024

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Human Primordial Germ Cells Are Specified from Lineage-Primed Progenitors.
Di Chen, Na Sun, Lei Hou, Rachel Kim, Jared Faith, Marianna Aslanyan, Yu Tao, Yi Zheng, Jianping Fu, Wanlu Liu

Cell Rep· December 2019

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Proteogenomics in cerebrospinal fluid and plasma reveals new biological fingerprint of cerebral small vessel disease.
Ilana Caro, Daniel Western, Shinichi Namba, Na Sun, Shuji Kawaguchi, Manolis Kellis

Nat Aging· December 2025

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Epigenetic control of metabolic identity across cell types.
Maria Pires Pacheco, Déborah Gerard, Riley J Mangan, Alec R Chapman, Dennis Hecker, Manolis Kellis

BMC Genomics· December 2025

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ABCA7 variants impact phosphatidylcholine and mitochondria in neurons.
Djuna von Maydell, Shannon E Wright, Ping-Chieh Pao, Colin Staab, Oisín King, Manolis Kellis

Nature· November 2025

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Multi-omics analysis of a pig-to-human decedent kidney xenotransplant.
Eloi Schmauch, Brian D Piening, Alexa K Dowdell, Maedeh Mohebnasab, Simon H Williams, Manolis Kellis

Nature· November 2025

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The hidden risk of round numbers and sharp thresholds in clinical practice.
Benjamin J Lengerich, Rich Caruana, Mark E Nunnally, Manolis Kellis

NPJ Digit Med· November 2025

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A chromatin fiber model explains cell-free DNA fragmentation signatures of active regulatory elements.
Alexis Yang, Garyoung Gary Lee, Surya Chhetri, Razane El Hajj Chehade, Gunsagar Gulati, Manolis Kellis

bioRxiv· November 2025

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ProCyon: A multimodal foundation model for protein phenotypes.
Owen Queen, Yepeng Huang, Robert Calef, Valentina Giunchiglia, Tianlong Chen, Manolis Kellis

bioRxiv· November 2025

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Melanoma to rhabdomyosarcoma plasticity in the setting of immunotherapy.
Andrew D Knight, Emily J Robitschek, Jia-Ren Lin, Dennie T Frederick, Alvin Shi, Manolis Kellis

medRxiv· November 2025

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PRISM: ancestry-aware integration of tissue-specific genomic annotations enhances the transferability of polygenic scores.
Xiaohe Tian, Tabassum Fabiha, William F Li, Kushal K Dey, Manolis Kellis

bioRxiv· November 2025

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CONCERT predicts niche-aware perturbation responses in spatial transcriptomics.
Xiang Lin, Zhenglun Kong, Soumya Ghosh, Manolis Kellis, Marinka Zitnik

bioRxiv· November 2025

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sc4D: spatio-temporal single-cell transcriptomics analysis through embedded optimal transport identifies joint glial response to Alzheimer's disease pathology.
Ishir Rao, Manolis Kellis, Yosuke Tanigawa

bioRxiv· November 2025

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Translon: a single term for translated regions.
Michał I Świrski, Jack A S Tierney, M Mar Albà, Dmitry E Andreev, Julie L Aspden, Manolis Kellis

Nat Methods· October 2025

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Molecular hallmarks of excitatory and inhibitory neuronal resilience to Alzheimer's disease.
Isabel Castanho, Pourya Naderi Yeganeh, Carles A Boix, Sarah L Morgan, Hansruedi Mathys, Manolis Kellis

Mol Neurodegener· October 2025

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Engineered 3D immuno-glial-neurovascular human miBrain model.
Alice E Stanton, Adele Bubnys, Emre Agbas, Benjamin James, Dong Shin Park, Manolis Kellis

Proc Natl Acad Sci U S A· October 2025

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Programmed ribosomal frameshifting during mRNA decoding generates a constitutively active proteoform that supports myocardial function.
Gary Loughran, Raffaella De Pace, Ningyu Ding, Jianchao Zhang, Irwin Jungreis, Manolis Kellis

Sci Adv· October 2025

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Integrating single-cell RNA-seq datasets with substantial batch effects.
Karin Hrovatin, Amir Ali Moinfar, Luke Zappia, Shrey Parikh, Alejandro Tejada Lapuerta, Manolis Kellis

BMC Genomics· October 2025

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Intraspecific sequence variation and complete genomes refine the identification of rapidly evolved regions in humans.
Yanting Luo, Riley J Mangan, Seth Weaver, Sarah A Zhao, Federica Mosti, Manolis Kellis

bioRxiv· October 2025

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Type 2 Diabetes and Obesity Alter Exercise Training-Induced Transcriptional Adaptations to Subcutaneous White Adipose Tissue.
Roeland J W Middelbeek, Jiekun Yang, Pasquale Nigro, Benjamin James, Danaé Papadopoulos, Manolis Kellis

bioRxiv· October 2025

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Single-cell multiregion epigenomic rewiring in Alzheimer's disease progression and cognitive resilience.
Zunpeng Liu, Shanshan Zhang, Benjamin T James, Kyriaki Galani, Riley J Mangan, Manolis Kellis

Cell· September 2025

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Mature and migratory dendritic cells promote immune infiltration and response to anti-PD-1 checkpoint blockade in metastatic melanoma.
Jiekun Yang, Cassia Wang, Doris Fu, Li-Lun Ho, Kyriakitsa Galani, Manolis Kellis

Nat Commun· September 2025

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An expanded reference catalog of translated open reading frames for biomedical research.
Sonia Chothani, Jorge Ruiz-Orera, Jack A S Tierney, Jim Clauwaert, Eric W Deutsch, Manolis Kellis

bioRxiv· July 2025

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Context-dependent regulatory variants in Alzheimer's disease.
Ziheng Chen, Yaxuan Liu, Ashley R Brown, Heather H Sestili, Easwaran Ramamurthy, Manolis Kellis

bioRxiv· July 2025

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Specific oncogene activation of the cell of origin in mucosal melanoma.
Swathy Babu, Jiajia Chen, Chloé S Baron, Kaiwen Sun, Emily Robitschek, Manolis Kellis

Nat Commun· July 2025

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Proteogenomics-enabled discovery of novel small open reading frame (sORF)-encoded polypeptides in human and mouse tissues.
Mei Yang, Yuting Xie, Lingshuo Wang, Irwin Jungreis, Tong Ou, Manolis Kellis

Nucleic Acids Res· July 2025

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A multimodal approach of microglial CSF1R inhibition and GENUS provides therapeutic effects in Alzheimer's disease mice.
Chinnakkaruppan Adaikkan, Md Rezaul Islam, P Lorenzo Bozzelli, Matt Sears, Cameron Parro, Manolis Kellis

bioRxiv· July 2025

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