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Publications by authors named "Manon Kiry"

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Discovery, synthesis and SAR of 3-aryl pyrazolidines, novel dual orexin receptor antagonists for the treatment of sleep disorders.
Jean-Philippe Surivet, Melanie Kessler, Catherine Vaillant, Jean-Christophe Gauvin, Manon Kiry

Bioorg Med Chem· November 2025


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Discovery of IDOR-1117-1680, a dual orexin receptor antagonist with fast onset and short duration of action for the treatment of insomnia.
Jean-Philippe Surivet, Elise M Jacob, Melanie Kessler, Christopher Kohl, Catherine Vaillant, Manon Kiry

Bioorg Med Chem· May 2025


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Discovery, synthesis and SAR of 2-acyl-1-biarylmethyl pyrazolidines, dual orexin receptor antagonists designed as fast and short-acting sleeping drugs.
Jean-Philippe Surivet, Melanie Kessler, Catherine Vaillant, Hamed Aissaoui, Olivier Bezençon, Manon Kiry

Bioorg Med Chem· October 2024


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