Publications by authors named "Manuel Portero-Otin"

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Genetic determinism of fatty acid composition in liver, muscle, backfat and plasma and its link to immunocompetence and performance in pigs.
Carles Hernández-Banqué, Junhui Liu, Teodor Jové-Juncà, Olga González-Rodríguez, Manuel Portero-Otín

Sci Rep· December 2025

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Mission cholesterol: Uncovering its hidden role in ALS neurodegeneration.
Anna Fernàndez-Bernal, Natàlia Mota, Reinald Pamplona, Estela Area-Gómez, Manuel Portero-Otin

Biochim Biophys Acta Mol Basis Dis· November 2025

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Mitochondrial lipidome's fatty acid profile and peroxidation index are programmed tissue-specific traits.
Natàlia Mota-Martorell, Anna Fernàndez-Bernal, Joaquim Sol, Marta Santacreu-Vilaseca, Alba Juanes-Casado

Redox Biol· October 2025

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Exploring platelet metabolomics and fatty acid profiles for ALS prognosis and diagnosis.
Pascual Torres, Irene Pradas, Anna Fernàndez-Bernal, Mònica Povedano, Raul Dominguez, Manuel Portero-Otin

Sci Rep· October 2025

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Ether lipids and sphingolipids drive sex-specific human aging dynamics.
Joaquim Sol, Anna Fernàndez-Bernal, Natalia Mota-Martorell, Meritxell Martín-Garí, Èlia Obis

Redox Biol· September 2025

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Non-enzymatic modification of aminophospholipids induces angiogenesis, inflammation, and insulin signaling dysregulation in human renal glomerular endothelial cells in vitro.
Reyna Rodríguez-Mortera, Pascual Torres, Anna Fernàndez-Bernal, Rebeca Berdún, Omar Ramírez-Núñez, Manuel Portero-Otin

Free Radic Biol Med· August 2025

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TDP-43 loss-of-function triggers mitochondrial dysfunction and metabolic imbalance.
Miriam Ceron-Codorniu, Anna Fernàndez-Bernal, Reinald Pamplona, Manuel Portero-Otín

Neural Regen Res· July 2025

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Examining the complex Interplay between gut microbiota abundance and short-chain fatty acid production in amyotrophic lateral sclerosis patients shortly after onset of disease.
Laia Fontdevila, Mònica Povedano, Raúl Domínguez, Jordi Boada, José Ce Serrano

Sci Rep· October 2024

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TDP-43 dysfunction leads to bioenergetic failure and lipid metabolic rewiring in human cells.
Miriam Ceron-Codorniu, Pascual Torres, Anna Fernàndez-Bernal, Santiago Rico-Rios, José Ce Serrano

Redox Biol· September 2024

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TDP-43 regulates LC3ylation in neural tissue through ATG4B cryptic splicing inhibition.
Pascual Torres, Santiago Rico-Rios, Miriam Ceron-Codorniu, Marta Santacreu-Vilaseca, David Seoane-Miraz, Manuel Portero-Otin

Acta Neuropathol· September 2024

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Glycogen accumulation modulates life span in a mouse model of amyotrophic lateral sclerosis.
M Kathryn Brewer, Pascual Torres, Victòria Ayala, Manuel Portero-Otin, Reinald Pamplona

J Neurochem· May 2024

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Human lifespan and sex-specific patterns of resilience to disease: a retrospective population-wide cohort study.
Joaquim Sol, Marta Ortega-Bravo, Manuel Portero-Otín, Gerard Piñol-Ripoll, Vicent Ribas-Ripoll

BMC Med· January 2024

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High-Fat Diet-Induced Obesity Increases Brain Mitochondrial Complex I and Lipoxidation-Derived Protein Damage.
Rebeca Berdún, Èlia Obis, Natàlia Mota-Martorell, Anna Bassols, Daniel Valent

Antioxidants (Basel)· January 2024

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Phenotypic molecular features of long-lived animal species.
Mariona Jové, Natàlia Mota-Martorell, Anna Fernàndez-Bernal, Manuel Portero-Otin, Gustavo Barja

Free Radic Biol Med· November 2023

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Lipidomic Alterations in the Cerebral Cortex and White Matter in Sporadic Alzheimer's Disease.
Elia Obis, Joaquim Sol, Pol Andres-Benito, Meritxell Martín-Gari, Natàlia Mota-Martorell, Manuel Portero-Otin

Aging Dis· October 2023

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Cell senescence, loss of splicing, and lipid metabolism in TDP-43-related neurodegenerative processes.
Pascual Torres, Reinald Pamplona, Manuel Portero-Otin

Neural Regen Res· August 2023

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Hakuna MAM-Tata: Investigating the role of mitochondrial-associated membranes in ALS.
Anna Fernàndez Bernal, Natàlia Mota, Reinald Pamplona, Estela Area-Gomez, Manuel Portero-Otin

Biochim Biophys Acta Mol Basis Dis· August 2023

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Antihypertensive Effects of an Optimized Aged Garlic Extract in Subjects with Grade I Hypertension and Antihypertensive Drug Therapy: A Randomized, Triple-Blind Controlled Trial.
José C E Serrano, Eva Castro-Boqué, Alicia García-Carrasco, María Inés Morán-Valero, Daniel González-Hedström

Nutrients· August 2023

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Plasma acylcarnitines and gut-derived aromatic amino acids as sex-specific hub metabolites of the human aging metabolome.
Joaquim Sol, Èlia Obis, Natalia Mota-Martorell, Irene Pradas, Jose Daniel Galo-Licona, Manuel Portero-Otin

Aging Cell· June 2023

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Dietary Advanced Glycation End Products: Their Role in the Insulin Resistance of Aging.
Manuel Portero-Otin, M Pia de la Maza, Jaime Uribarri

Cells· June 2023

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Cyanovirin-N binds to select SARS-CoV-2 spike oligosaccharides outside of the receptor binding domain and blocks infection by SARS-CoV-2.
Jordana Muñoz-Basagoiti, Fábio Luís Lima Monteiro, Lauren R H Krumpe, Victoria Armario-Najera, Shilpa R Shenoy, Manuel Portero-Otin

Proc Natl Acad Sci U S A· March 2023

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Lipid Adaptations against Oxidative Challenge in the Healthy Adult Human Brain.
Mariona Jové, Natàlia Mota-Martorell, Èlia Obis, Joaquim Sol, Meritxell Martín-Garí

Antioxidants (Basel)· January 2023

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Ether Lipid-Mediated Antioxidant Defense in Alzheimer's Disease.
Mariona Jové, Natàlia Mota-Martorell, Èlia Obis, Joaquim Sol, Meritxell Martín-Garí, Manuel Portero-Otin

Antioxidants (Basel)· January 2023

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DPP9 as a Potential Novel Mediator in Gastrointestinal Virus Infection.
Ángela Del Castillo-Izquierdo, José María Moreno-Navarrete, Jessica Latorre, María Arnoriaga-Rodríguez, Marta Ballanti

Antioxidants (Basel)· November 2022

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A motor neuron disease mouse model reveals a non-canonical profile of senescence biomarkers.
Pascual Torres, Carlos Anerillas, Omar Ramírez-Núñez, Anna Fernàndez, Mario Encinas

Dis Model Mech· August 2022

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