Publications by authors named "Manuela Cominelli"

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Didox, a ribonucleotide reductase inhibitor with iron chelator properties, counteracts the in vitro and in vivo growth of rhabdomyosarcoma cells.
Luca Cantamessa, Michela Asperti, Magdalena Gryzik, Silvia Codenotti, Leonardo Sandrini, Manuela Cominelli

Biochem Pharmacol· December 2025

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Non-invasive identification of mesenchymal glioblastoma using quantitative radiomic features from advanced diffusion MRI: a preclinical-to-clinical transfer learning strategy.
Alberto L Gallotti, Nicolò Pecco, Valentina Pieri, Manuela Cominelli, Gianluca Brugnara

Eur Radiol Exp· November 2025

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Concurrent RB1 and P53 pathway disruption predisposes to the development of a primitive neuronal component in high-grade gliomas depending on MYC-driven EBF3 transcription.
Francesca Pagani, Francesca Orzan, Sara Lago, Francesca De Bacco, Marta Prelli, Manuela Cominelli

Acta Neuropathol· January 2025

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Tumor heterogeneity and tumor-microglia interactions in primary and recurrent IDH1-mutant gliomas.
Enrique Blanco-Carmona, Ashwin Narayanan, Inmaculada Hernandez, Juan C Nieto, Marc Elosua-Bayes, Manuela Cominelli

Cell Rep Med· November 2023

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Coexisting cancer stem cells with heterogeneous gene amplifications, transcriptional profiles, and malignancy are isolated from single glioblastomas.
Francesca De Bacco, Francesca Orzan, Giovanni Crisafulli, Marta Prelli, Claudio Isella, Manuela Cominelli

Cell Rep· August 2023

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Human iPSC-Derived 3D Hepatic Organoids in a Miniaturized Dynamic Culture System.
Serena Calamaio, Marialaura Serzanti, Jennifer Boniotti, Annamaria Fra, Emirena Garrafa, Manuela Cominelli

Biomedicines· July 2023

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Exceptionally rare IDH1-mutant adult medulloblastoma with concurrent GNAS mutation revealed by in vivo magnetic resonance spectroscopy and deep sequencing.
Roberto Liserre, Francesca Branzoli, Francesca Pagani, Magdalena Gryzik, Manuela Cominelli

Acta Neuropathol Commun· March 2023

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Lactotroph PitNET/adenoma associated to granulomatous hypophysitis in a patient with Crohn's disease: A case report.
Alberto Pietrantoni, Simona Serioli, Manuela Cominelli, Giovanni Lodoli, Roberto Stefini

Neuropathology· February 2023

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Targeting mTOR Pathway in PTEN Deleted Newly Isolated Chordoma Cell Line.
Francesca Pagani, Magdalena Gryzik, Elena Somenza, Manuela Cominelli, Piera Balzarini

J Pers Med· February 2023

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Aberrant L-Fucose Accumulation and Increased Core Fucosylation Are Metabolic Liabilities in Mesenchymal Glioblastoma.
Valentina Pieri, Alberto L Gallotti, Denise Drago, Manuela Cominelli, Ilaria Pagano

Cancer Res· January 2023

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β-Galactosylceramidase Deficiency Causes Upregulation of Long Pentraxin-3 in the Central Nervous System of Krabbe Patients and Mice.
Daniela Coltrini, Adwaid Manu Krishna Chandran, Mirella Belleri, Pietro L Poliani, Manuela Cominelli

Int J Mol Sci· August 2022

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Sellar metastasis from clear cell sarcoma: Description of the first case.
Francesco Doglietto, Linda Daffini, Elena Fazzari, Manuela Cominelli, Francesca Pagani

Clin Neuropathol· May 2022

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Cytotoxic Effect of Progesterone, Tamoxifen and Their Combination in Experimental Cell Models of Human Adrenocortical Cancer.
Elisa Rossini, Mariangela Tamburello, Andrea Abate, Silvia Beretta, Martina Fragni, Manuela Cominelli

Front Endocrinol (Lausanne)· December 2021

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mTORC1 promotes malignant large cell/anaplastic histology and is a targetable vulnerability in SHH-TP53 mutant medulloblastoma.
Valentina Conti, Manuela Cominelli, Valentina Pieri, Alberto L Gallotti, Ilaria Pagano

JCI Insight· December 2021

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EBF1 is expressed in pericytes and contributes to pericyte cell commitment.
Francesca Pagani, Elisa Tratta, Patrizia Dell'Era, Manuela Cominelli, Pietro Luigi Poliani

Histochem Cell Biol· October 2021

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Leptomeningeal dissemination of anaplastic medullary cone astrocytoma: an unexpected findings in a patient with leptomeningeal enhancement and clinical history of multiple myeloma.
Linda Daffini, Francesca Pagani, Manuela Cominelli, Giovanni Lodoli, Andrea Tironi

Pathologica· August 2021

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A simplified integrated molecular and immunohistochemistry-based algorithm allows high accuracy prediction of glioblastoma transcriptional subtypes.
Francesca Orzan, Francesca Pagani, Manuela Cominelli, Luca Triggiani, Stefano Calza

Lab Invest· October 2020

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Author Correction: Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer's disease.
Yingyue Zhou, Wilbur M Song, Prabhakar S Andhey, Amanda Swain, Tyler Levy, Manuela Cominelli

Nat Med· June 2020

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Enhanced SPARCL1 expression in cancer stem cells improves preclinical modeling of glioblastoma by promoting both tumor infiltration and angiogenesis.
Filippo Gagliardi, Ashwin Narayanan, Alberto Luigi Gallotti, Valentina Pieri, Stefania Mazzoleni, Manuela Cominelli

Neurobiol Dis· February 2020

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Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer's disease.
Yingyue Zhou, Wilbur M Song, Prabhakar S Andhey, Amanda Swain, Tyler Levy, Manuela Cominelli

Nat Med· January 2020

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The proneural gene ASCL1 governs the transcriptional subgroup affiliation in glioblastoma stem cells by directly repressing the mesenchymal gene NDRG1.
Ashwin Narayanan, Filippo Gagliardi, Alberto L Gallotti, Stefania Mazzoleni, Manuela Cominelli

Cell Death Differ· September 2019

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Altered function of the glutamate-aspartate transporter GLAST, a potential therapeutic target in glioblastoma.
Cristina Corbetta, Natalia Di Ianni, Maria Grazia Bruzzone, Monica Patanè, Bianca Pollo, Manuela Cominelli

Int J Cancer· May 2019

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Tuberous sclerosis complex-associated CNS abnormalities depend on hyperactivation of mTORC1 and Akt.
Paola Zordan, Manuela Cominelli, Federica Cascino, Elisa Tratta, Pietro L Poliani

J Clin Invest· April 2018

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Cavin-2 is a specific marker for detection of well-differentiated liposarcoma.
Silvia Codenotti, Marika Vezzoli, Pietro Luigi Poliani, Manuela Cominelli, Eugenio Monti

Biochem Biophys Res Commun· November 2017

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Treatment with anti-FcεRIα antibody exacerbates EAE and T-cell immunity against myelin.
Silvia Musio, Massimo Costanza, Pietro Luigi Poliani, Elena Fontana, Manuela Cominelli

Neurol Neuroimmunol Neuroinflamm· May 2017

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