Publications by authors named "Manuela Iezzi"

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Liver-specific BAG3 knockout delays chemically induced hepatocellular carcinoma development.
Verena Damiani, Erika Pizzinato, Federica Di Marco, Alessia Lamolinara, Francesco Del Pizzo, Manuela Iezzi

FEBS J· January 2026

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Systematic Phenotyping and Molecular Analysis of the Woozy Mouse: A Preclinical Model of Cerebellar Ataxia.
Fabio Bellia, Laura Amodei, Anna Giulia Ruggieri, Francesca Potenza, Marianna Viele, Manuela Iezzi

Mol Neurobiol· December 2025

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IL-7 promotes the formation of DNA double strand breaks and DNA repair in murine pro-B cells.
Alessia Lamolinara, Chiara Di Lisio, Julie A Hixon, Pasquale Simeone, Antonella De Cola, Manuela Iezzi

Front Immunol· October 2025

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17(R)-Resolvin D1 protects against sickle cell-related inflammatory cardiomyopathy in humanized mice.
Enrica Federti, Domenico Mattoscio, Antonio Recchiuti, Alessandro Matte, Maria Monti, Manuela Iezzi

Blood· April 2025

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LGALS3BP antibody-drug conjugate enhances tumor-infiltrating lymphocytes and synergizes with immunotherapy to restrain neuroblastoma growth.
Ilaria Cela, Emily Capone, Asia Pece, Giulio Lovato, Pasquale Simeone, Manuela Iezzi

J Transl Med· April 2025

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Enhancing PDAC therapy: Decitabine-olaparib synergy targets KRAS-dependent tumors.
Giorgia Anastasio, Michela Felaco, Alessia Lamolinara, Francesco Del Pizzo, Elisa Cacciagrano, Manuela Iezzi

iScience· February 2025

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EV20/Omomyc: A novel dual MYC/HER3 targeting immunoconjugate.
Sandra Bibbò, Emily Capone, Giulio Lovato, Sara Ponziani, Alessia Lamolinara, Manuela Iezzi

J Control Release· October 2024

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Pancreatic beta-cell specific BAG3 knockout results in chronic hyperinsulinemia inducing insulin resistance.
Verena Damiani, Alessia Lamolinara, Ilaria Cicalini, Maria Concetta Cufaro, Francesco Del Pizzo, Manuela Iezzi

Mol Metab· August 2023

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The 2EF Antibody Targets a Unique N-Terminal Epitope of Trop-2 and Enhances the In Vivo Activity of the Cancer-Selective 2G10 Antibody.
Emanuela Guerra, Marco Trerotola, Valeria Relli, Rossano Lattanzio, Martina Ceci, Manuela Iezzi

Cancers (Basel)· July 2023

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3D-Informed Targeting of the Trop-2 Signal-Activation Site Drives Selective Cancer Vulnerability.
Emanuela Guerra, Marco Trerotola, Valeria Relli, Rossano Lattanzio, Romina Tripaldi, Manuela Iezzi

Mol Cancer Ther· June 2023

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Duality of Nrf2 in iron-overload cardiomyopathy.
Enrica Federti, Francesca Vinchi, Iana Iatcenko, Alessandra Ghigo, Alessandro Matte, Manuela Iezzi

Haematologica· May 2023

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p140Cap inhibits β-Catenin in the breast cancer stem cell compartment instructing a protective anti-tumor immune response.
Vincenzo Salemme, Mauro Vedelago, Alessandro Sarcinella, Federico Moietta, Alessio Piccolantonio, Manuela Iezzi

Nat Commun· May 2023

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CAR-T-Derived Extracellular Vesicles: A Promising Development of CAR-T Anti-Tumor Therapy.
Sara Pagotto, Pasquale Simeone, Davide Brocco, Giulia Catitti, Domenico De Bellis, Manuela Iezzi

Cancers (Basel)· February 2023

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HER2-Displaying M13 Bacteriophages induce Therapeutic Immunity against Breast Cancer.
Junbiao Wang, Alessia Lamolinara, Laura Conti, Mara Giangrossi, Lishan Cui, Manuela Iezzi

Cancers (Basel)· August 2022

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Blood Circulating CD133+ Extracellular Vesicles Predict Clinical Outcomes in Patients with Metastatic Colorectal Cancer.
Davide Brocco, Pasquale Simeone, Davide Buca, Pietro Di Marino, Michele De Tursi, Manuela Iezzi

Cancers (Basel)· March 2022

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Fatal cytokine release syndrome by an aberrant FLIP/STAT3 axis.
Chiara Musiu, Simone Caligola, Alessandra Fiore, Alessia Lamolinara, Cristina Frusteri, Piera Amelia Iezzi, Manuela Iezzi

Cell Death Differ· February 2022

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Interrupting the nitrosative stress fuels tumor-specific cytotoxic T lymphocytes in pancreatic cancer.
Francesco De Sanctis, Alessia Lamolinara, Federico Boschi, Chiara Musiu, Simone Caligola, Manuela Iezzi

J Immunother Cancer· January 2022

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Role of ADCC, CDC, and CDCC in Vaccine-Mediated Protection against Her2 Mammary Carcinogenesis.
Marco Macagno, Silvio Bandini, Elisabetta Bolli, Amanda Bello, Federica Riccardo, Manuela Iezzi

Biomedicines· January 2022

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Arginase 1-Based Immune Modulatory Vaccines Induce Anticancer Immunity and Synergize with Anti-PD-1 Checkpoint Blockade.
Mia Aaboe Jørgensen, Stefano Ugel, Mie Linder Hübbe, Marco Carretta, Maria Perez-Penco, Manuela Iezzi

Cancer Immunol Res· November 2021

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Resolvin D1 and D2 reduce SARS-CoV-2-induced inflammatory responses in cystic fibrosis macrophages.
Antonio Recchiuti, Sara Patruno, Domenico Mattoscio, Elisa Isopi, Antonella Pomilio, Manuela Iezzi

FASEB J· April 2021

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Resolvin D1 reduces cancer growth stimulating a protective neutrophil-dependent recruitment of anti-tumor monocytes.
Domenico Mattoscio, Elisa Isopi, Alessia Lamolinara, Sara Patruno, Alessandro Medda, Manuela Iezzi

J Exp Clin Cancer Res· April 2021

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Deciphering the state of immune silence in fatal COVID-19 patients.
Pierre Bost, Francesco De Sanctis, Stefania Canè, Stefano Ugel, Katia Donadello, Manuela Iezzi

Nat Commun· March 2021

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Improvement of urinary tract symptoms and quality of life in benign prostate hyperplasia patients associated with consumption of a newly developed whole tomato-based food supplement: a phase II prospective, randomized double-blinded, placebo-controlled study.
Luigi Cormio, Beppe Calò, Ugo Falagario, Manuela Iezzi, Alessia Lamolinara

J Transl Med· January 2021

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Enhanced Expression of in B Cells of CLL Improves the Anti-Tumor Cytotoxic T Cell Response.
Mirco Di Marco, Serena Veschi, Paola Lanuti, Alice Ramassone, Stefania Pacillo, Manuela Iezzi

Cancers (Basel)· January 2021

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Targeting Vesicular LGALS3BP by an Antibody-Drug Conjugate as Novel Therapeutic Strategy for Neuroblastoma.
Emily Capone, Alessia Lamolinara, Fabio Pastorino, Roberta Gentile, Sara Ponziani, Manuela Iezzi

Cancers (Basel)· October 2020

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