Publications by authors named "Manuela Minguzzi"

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IKKα affects the susceptibility of primary human osteoarthritis chondrocytes to oxidative stress-induced DNA damage by tuning autophagy.
Simona Neri, Serena Guidotti, Veronica Panichi, Manuela Minguzzi, Luca Cattini

Free Radic Biol Med· November 2024

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Basal and IL-1β enhanced chondrocyte chemotactic activity on monocytes are co-dependent on both IKKα and IKKβ NF-κB activating kinases.
Eleonora Olivotto, Manuela Minguzzi, Stefania D'Adamo, Annalisa Astolfi, Spartaco Santi

Sci Rep· November 2021

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Pleiotropic Roles of NOTCH1 Signaling in the Loss of Maturational Arrest of Human Osteoarthritic Chondrocytes.
Manuela Minguzzi, Veronica Panichi, Stefania D'Adamo, Silvia Cetrullo, Luca Cattini

Int J Mol Sci· November 2021

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Oxidative stress-induced DNA damage and repair in primary human osteoarthritis chondrocytes: focus on IKKα and the DNA Mismatch Repair System.
Simona Neri, Serena Guidotti, Carla Bini, Susi Pelotti, Stefania D'Adamo, Manuela Minguzzi

Free Radic Biol Med· April 2021

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Spermidine rescues the deregulated autophagic response to oxidative stress of osteoarthritic chondrocytes.
Stefania D'Adamo, Silvia Cetrullo, Serena Guidotti, Ylenia Silvestri, Manuela Minguzzi

Free Radic Biol Med· June 2020

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Polyamine supplementation reduces DNA damage in adipose stem cells cultured in 3-D.
Manuela Minguzzi, Serena Guidotti, Daniela Platano, Stefania D'Adamo, Silvia Cetrullo

Sci Rep· October 2019

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The N-Acetyl Phenylalanine Glucosamine Derivative Attenuates the Inflammatory/Catabolic Environment in a Chondrocyte-Synoviocyte Co-Culture System.
Stefania Pagani, Manuela Minguzzi, Laura Sicuro, Francesca Veronesi, Spartaco Santi

Sci Rep· September 2019

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"Spermidine restores dysregulated autophagy and polyamine synthesis in aged and osteoarthritic chondrocytes via EP300".
Rosa Maria Borzì, Silvia Cetrullo, Stefania D'Adamo, Manuela Minguzzi, Flavio Flamigni

Exp Mol Med· March 2019

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Emerging Players at the Intersection of Chondrocyte Loss of Maturational Arrest, Oxidative Stress, Senescence and Low-Grade Inflammation in Osteoarthritis.
Manuela Minguzzi, Silvia Cetrullo, Stefania D'Adamo, Ylenia Silvestri, Flavio Flamigni

Oxid Med Cell Longev· September 2018

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MicroRNAs and Autophagy: Fine Players in the Control of Chondrocyte Homeostatic Activities in Osteoarthritis.
Stefania D'Adamo, Silvia Cetrullo, Manuela Minguzzi, Ylenia Silvestri, Rosa Maria Borzì

Oxid Med Cell Longev· April 2018

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Short-term treatment with eicosapentaenoic acid improves inflammation and affects colonic differentiation markers and microbiota in patients with ulcerative colitis.
Anna Prossomariti, Eleonora Scaioli, Giulia Piazzi, Chiara Fazio, Matteo Bellanova, Manuela Minguzzi

Sci Rep· August 2017

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Lithium Chloride Dependent Glycogen Synthase Kinase 3 Inactivation Links Oxidative DNA Damage, Hypertrophy and Senescence in Human Articular Chondrocytes and Reproduces Chondrocyte Phenotype of Obese Osteoarthritis Patients.
Serena Guidotti, Manuela Minguzzi, Daniela Platano, Luca Cattini, Giovanni Trisolino

PLoS One· July 2016

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Molecular and proteomic insight into Notch1 characterization in hepatocellular carcinoma.
Catia Giovannini, Manuela Minguzzi, Filippo Genovese, Michele Baglioni, Alessandra Gualandi

Oncotarget· June 2016

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Hydroxytyrosol prevents increase of osteoarthritis markers in human chondrocytes treated with hydrogen peroxide or growth-related oncogene α.
Annalisa Facchini, Silvia Cetrullo, Stefania D'Adamo, Serena Guidotti, Manuela Minguzzi

PLoS One· January 2016

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Suppression of p53 by Notch3 is mediated by Cyclin G1 and sustained by MDM2 and miR-221 axis in hepatocellular carcinoma.
Catia Giovannini, Manuela Minguzzi, Michele Baglioni, Francesca Fornari, Ferdinando Giannone

Oncotarget· November 2014

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Polyamine delivery as a tool to modulate stem cell differentiation in skeletal tissue engineering.
Rosa Maria Borzì, Serena Guidotti, Manuela Minguzzi, Annalisa Facchini, Daniela Platano

Amino Acids· March 2014

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Enhanced osteoblastogenesis of adipose-derived stem cells on spermine delivery via β-catenin activation.
Serena Guidotti, Annalisa Facchini, Daniela Platano, Eleonora Olivotto, Manuela Minguzzi

Stem Cells Dev· May 2013

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CDKN1C/P57 is regulated by the Notch target gene Hes1 and induces senescence in human hepatocellular carcinoma.
Catia Giovannini, Laura Gramantieri, Manuela Minguzzi, Francesca Fornari, Pasquale Chieco

Am J Pathol· August 2012

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Design, synthesis and biological evaluation of pyrazole derivatives as potential multi-kinase inhibitors in hepatocellular carcinoma.
Elena Strocchi, Francesca Fornari, Manuela Minguzzi, Laura Gramantieri, Maddalena Milazzo

Eur J Med Chem· February 2012

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Selective ablation of Notch3 in HCC enhances doxorubicin's death promoting effect by a p53 dependent mechanism.
Catia Giovannini, Laura Gramantieri, Pasquale Chieco, Manuela Minguzzi, Federica Lago

J Hepatol· May 2009

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