Publications by authors named "Manuela Simonetti"

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Neuron-astrocyte metabolic coupling facilitates spinal plasticity and maintenance of inflammatory pain.
Sebastián Marty-Lombardi, Shiying Lu, Wojciech Ambroziak, Katrin Schrenk-Siemens, Jialin Wang, Manuela Simonetti

Nat Metab· March 2024

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Cellular and Molecular Mechanisms Underlying Pain Chronicity.
Manuela Simonetti, Daniela Mauceri

Cells· April 2023

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Activation of β2-Adrenergic Receptors in Microglia Alleviates Neuropathic Hypersensitivity in Mice.
Elisa Damo, Amit Agarwal, Manuela Simonetti

Cells· January 2023

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Axon Guidance Molecules and Pain.
Elisa Damo, Manuela Simonetti

Cells· October 2022

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The Macrophage Iron Signature in Health and Disease.
Christina Mertens, Oriana Marques, Natalie K Horvat, Manuela Simonetti, Martina U Muckenthaler

Int J Mol Sci· August 2021

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Locus revealed: Painlessness via loss of Na1.7 at central terminals of sensory neurons.
Manuela Simonetti, Rohini Kuner

Neuron· May 2021

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The impact of Semaphorin 4C/Plexin-B2 signaling on fear memory via remodeling of neuronal and synaptic morphology.
Manuela Simonetti, Eszter Paldy, Christian Njoo, Kiran Kumar Bali, Thomas Worzfeld

Mol Psychiatry· April 2021

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CXCL10 and CCL21 Promote Migration of Pancreatic Cancer Cells Toward Sensory Neurons and Neural Remodeling in Tumors in Mice, Associated With Pain in Patients.
Michael Hirth, Jagadeesh Gandla, Christiane Höper, Matthias M Gaida, Nitin Agarwal, Manuela Simonetti

Gastroenterology· August 2020

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Spinal Wnt5a Plays a Key Role in Spinal Dendritic Spine Remodeling in Neuropathic and Inflammatory Pain Models and in the Proalgesic Effects of Peripheral Wnt3a.
Manuela Simonetti, Rohini Kuner

J Neurosci· August 2020

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Semaphorin 4C Plexin-B2 signaling in peripheral sensory neurons is pronociceptive in a model of inflammatory pain.
Eszter Paldy, Manuela Simonetti, Thomas Worzfeld, Kiran Kumar Bali, Lucas Vicuña

Nat Commun· August 2017

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WNT signaling mechanisms in nociception and sensitization of afferent neurons.
Manuela Simonetti

Springerplus· July 2016

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The serine protease inhibitor SerpinA3N attenuates neuropathic pain by inhibiting T cell-derived leukocyte elastase.
Lucas Vicuña, David E Strochlic, Alban Latremoliere, Kiran Kumar Bali, Manuela Simonetti

Nat Med· May 2015

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Neuronal calcium signaling in chronic pain.
Anna M Hagenston, Manuela Simonetti

Cell Tissue Res· August 2014

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Wnt-Fzd signaling sensitizes peripheral sensory neurons via distinct noncanonical pathways.
Manuela Simonetti, Nitin Agarwal, Sebastian Stösser, Kiran Kumar Bali, Emil Karaulanov

Neuron· July 2014

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Mutated CaV2.1 channels dysregulate CASK/P2X3 signaling in mouse trigeminal sensory neurons of R192Q Cacna1a knock-in mice.
Aswini Gnanasekaran, Tanja Bele, Swathi Hullugundi, Manuela Simonetti, Michael D Ferrari

Mol Pain· December 2013

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Nuclear calcium signaling in spinal neurons drives a genomic program required for persistent inflammatory pain.
Manuela Simonetti, Anna M Hagenston, Daniel Vardeh, H Eckehard Freitag, Daniela Mauceri

Neuron· January 2013

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Cystic fibrosis transmembrane conductance regulator modulates synaptic chloride homeostasis in motoneurons of the rat spinal cord during neonatal development.
Alexey Ostroumov, Manuela Simonetti, Andrea Nistri

Dev Neurobiol· March 2011

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Familial hemiplegic migraine Ca(v)2.1 channel mutation R192Q enhances ATP-gated P2X3 receptor activity of mouse sensory ganglion neurons mediating trigeminal pain.
Asha Nair, Manuela Simonetti, Nicol Birsa, Michel D Ferrari, Arn M J M van den Maagdenberg

Mol Pain· August 2010

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The Cdk5 kinase downregulates ATP-gated ionotropic P2X3 receptor function via serine phosphorylation.
Asha Nair, Manuela Simonetti, Elsa Fabbretti, Andrea Nistri

Cell Mol Neurobiol· May 2010

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Mechanisms mediating the enhanced gene transcription of P2X3 receptor by calcitonin gene-related peptide in trigeminal sensory neurons.
Manuela Simonetti, Rashid Giniatullin, Elsa Fabbretti

J Biol Chem· July 2008

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Neutralization of nerve growth factor induces plasticity of ATP-sensitive P2X3 receptors of nociceptive trigeminal ganglion neurons.
Marianna D'Arco, Rashid Giniatullin, Manuela Simonetti, Alessandra Fabbro, Asha Nair

J Neurosci· August 2007

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Delayed upregulation of ATP P2X3 receptors of trigeminal sensory neurons by calcitonin gene-related peptide.
Elsa Fabbretti, Marianna D'Arco, Alessandra Fabbro, Manuela Simonetti, Andrea Nistri

J Neurosci· June 2006

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Comparison of P2X and TRPV1 receptors in ganglia or primary culture of trigeminal neurons and their modulation by NGF or serotonin.
Manuela Simonetti, Alessandra Fabbro, Marianna D'Arco, Marina Zweyer, Andrea Nistri

Mol Pain· March 2006

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