Publications by authors named "Marawan Elbaset"

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Sotagliflozin Modulation of SIRT1/Nrf2 and PI3K/AKT Signaling Pathway Ameliorates Experimental Liver Fibrosis in Rats.
Hossein M Elbadawy, Mohannad A Almikhlafi, Mohammed H Alsubhi, Aya A Shokry, Hany M Fayed, Marawan A Elbaset

Oxid Med Cell Longev· January 2026

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Linagliptin attenuates kidney cancer in rats via AMPK activation and suppression of YAP/TAZ/HIF-1α signaling.
Tahani Saeedi, Mohannad Almikhlafi, Hossein M Elbadawy, Muayad S Albadrani, Rehab F Abdel-Rahman, Marawan A Elbaset

Eur J Pharm Sci· December 2025

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Unveiling phytoconstituents and the anti-inflammatory potential of Crassula tetragona L. in ulcerative colitis: A focus on the PPARγ/SIRT1 axis.
Mona A Raslan, Rehab F Abdel-Rahman, Hany M Fayed, Marawan A Elbaset, Rehab F Taher

Inflammopharmacology· December 2025

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Therapeutic efficacy of canagliflozin against hepatocarcinogenesis induced by CDD/DEN/TAA in a rat model: regulation of AMPK/HIF-1α/YAP-1/TAZ signaling pathways.
Hany M Fayed, Gihan F Asaad, Marawan A Elbaset, Ola A Sharaf, Sawsan S Mahmoud

Naunyn Schmiedebergs Arch Pharmacol· November 2025

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Cilostazol ameliorates Cisplatin-induced nephrotoxicity via modulation of PI3K/AKT/mTOR signaling pathway and autophagy in rats.
Salma A El-Marasy, Nesma M E Abo El-Nasr, Dina E ElMosbah, Marawan Elbaset

Toxicol Mech Methods· November 2025

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Short-term effects of sertraline against depressive-like behaviors in a rat model of neonatal hypoxic encephalopathy.
Marie-Michèle Serghani, Sondos Kassem-Moussa, Rawan Makki, Abdallah Kurdi, Marawan Elbaset

Neurosci Lett· November 2025

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Therapeutic potential of canagliflozin in DEN/TAA-induced renal cancer: mechanistic insights into NLRP3/IL-6/STAT3 and AMPK signaling and oxidative stress regulation.
Rehab F Abdel-Rahman, Mahdi H Alsugoor, Naif ALSuhaymi, Hany M Fayed, Sawsan S Mahmoud, Marawan A Elbaset

Saudi Pharm J· October 2025

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Repositioning gemigliptin for the alleviation of thioacetamide-induced liver fibrosis in rats: Targeting TLR4/MAPK, SIRT1/AMPK/Nrf2, PI3K/AKT/mTOR axis and apoptosis.
Riyadh S Almalki, Malaz Gazzaz, Samar F Miski, Hany M Fayed, Bassim M S A Mohamed, Marawan A Elbaset

Eur J Pharm Sci· September 2025

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Design, Synthesis, Biological Evaluation, and Computational Studies of Novel 1,4-Diketopiperazines as GABA Agonist.
Mostafa Abd El-Mohsen Anwar, Eman R Mohammed, Samir M El Moghazy, Nesma M E Abo El Nasr, Marawan A Elbaset

Drug Dev Res· August 2025

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Role of rosuvastatin and pitavastatin in alleviating diabetic cardiomyopathy in rats: Targeting of RISK, NF-κB/ NLRP3 inflammasome and TLR4/ NF-κB signaling cascades.
Dalia O Saleh, Nesma M E Abo El Nasr, Marawan A Elbaset, Marwa E Shabana, Tuba Esatbeyoglu

PLoS One· July 2025

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Design and synthesis of novel cyclohexanecarboxamides with anticonvulsant effect by activating Nrf2-ARE pathway.
Walaa H Abd-Allah, Mohammed S Abdel-Maksoud, Marawan A Elbaset, Reda M S Korany, Ibrahim M Ibrahim

Bioorg Chem· June 2025

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Chrysin mitigates cyclophosphamide-triggered cardiotoxicity in rats: Insights into cardioprotection via Treg expression modulation and iNOS downregulation.
Dalia O Saleh, Marawan A Elbaset, Kawkab A Ahmed, Ahmed A Sedik

Toxicol Rep· June 2025

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Astaxanthin mitigates diabetic cardiomyopathy and nephropathyin HF/HFr/STZ diabetic rats via modulating NOX4, fractalkine, Nrf2, and AP-1 pathways.
Nesma M E Abo El-Nasr, Yosra A Hussien, Marawan Abd El-Baset, Marwa E Shabana, Dalia O Saleh

Sci Rep· June 2025

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Protective role of remogliflozin against experimental liver fibrosis by activating AMPK/SIRT1/Nrf2 and suppressing NF-κB pathways.
Naif ALSuhaymi, Mahdi H Alsugoor, Aya A Shokry, Hany M Fayed, Bassim M S A Mohamed, Marawan A Elbaset

Front Pharmacol· June 2025

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Hepatoprotective action of Sonchus oleraceus against paracetamol-induced toxicity via Nrf2/KEAP-1/HO-1 pathway in relation to its metabolite fingerprint and in silico studies.
Mohamed F Abdelhameed, Marawan A El-Baset, Amira R Khattab, Rehab F Taher, Mohamed A El-Saied

PLoS One· June 2025

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Cyclophosphamide-induced testicular injury: the role of chrysin in mitigating iron overload and ferroptosis.
Dalia O Saleh, Nesma M E Abo El Nasr, Yosra A Hussien, Marawan Abd El-Baset, Kawkab A Ahmed

Naunyn Schmiedebergs Arch Pharmacol· May 2025

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Unveiling the potency of ZnO and CuO nanocomposites in combating hepatocellular carcinoma by inducing cell death and suppressing migration.
Rasha M Allam, Nesma M E Abo El-Nasr, Marawan A Elbaset, Dalia O Saleh, Ahmed M A El-Seidy

Sci Rep· May 2025

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Zinc sulphate attenuates metabolic dysfunctions induced by olanzapine via the reduction of insulin resistance, hepatic oxidative stress, and inflammation in albino rats.
Samir A E Bashandy, Rasha E Mostafa, Marawan A El-Baset, Fatma A A Ibrahim, Fatma A Morsy

BMC Pharmacol Toxicol· April 2025

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, with (-)-Pseudosemiglabrin as the Major Constituent, Alleviates Severe Acute Pancreatitis-Mediated Acute Lung Injury by Modulating HMGB1 and IL-22.
Gamal A Soliman, Mohammed A Alamri, Rehab F Abdel-Rahman, Marawan A Elbaset, Hanan A Ogaly

Int J Mol Sci· March 2025

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Baicalin nanoemulsion mitigates cisplatin-induced hepatotoxicity by alleviating oxidative stress, inflammation, and restoring cellular integrity.
Hadir Farouk, Maha Nasr, Marawan Abd Elbaset, Marwa E Shabana, Omar A H Ahmed-Farid

Toxicol Appl Pharmacol· February 2025

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Deferiprone ameliorates cisplatin induced peripheral neurotoxicity via ferritinophagy adjustment.
Hanan Seddiek, Mira Hanna, Amany Elsayed Mohamed Hamoud, Marawan Abd Elbaset, Ahmed M A Akabawy

Sci Rep· February 2025

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Management of cardiovascular disease by cerium oxide nanoparticles via alleviating oxidative stress and adipokine abnormalities.
Samir A E Bashandy, Marawan A Elbaset, Fatma A A Ibrahim, Sahar S Abdelrahman, Sherif A Abdelmottaleb Moussa

Sci Rep· February 2025

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Intracellular iron accumulation throughout the progression of sepsis influences the phenotype and function of activated macrophages in renal tissue damage.
Mira Hanna, Ahmed M A Akabawy, Mohamed Mansour Khalifa, Marawan Abd Elbaset, Reda Abdelnasser Imam

Front Physiol· January 2025

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Neuroprotective Effects of Trimetazidine against Cisplatin-Induced Peripheral Neuropathy: Involvement of AMPK-Mediated PI3K/mTOR, Nrf2, and NF-B Signaling Axes.
Marawan A Elbaset, Sherif M Afifi, Tuba Esatbeyoglu, Sahar S Abdelrahman, Dalia O Saleh

Oxid Med Cell Longev· November 2024

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Efficacy of goldenberry in improving obesity-induced hemoglobin conformational structure changes in wistar rats: A biophysical perspective.
Sherif A Abdelmottaleb Moussa, Samir W Aziz, Samir A Bashandy, Marawan Abd Elbaset, Noha A Abd El-Latif

Heliyon· November 2024

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