Publications by authors named "Marc Beal"

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Impacts of Inorganic Arsenic Exposure on Genetic Stability of Human Mesenchymal Stromal Cells.
Marc A Beal, Melanie Coughlan, Andrée Nunnikhoven, Reena Corbane, Cathy Cummings-Lorbetskie

J Appl Toxicol· August 2025

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In vitro to in vivo extrapolation modeling to facilitate the integration of transcriptomics data into genotoxicity assessment.
Anouck Thienpont, Eunnara Cho, Andrew Williams, Matthew J Meier, Carole L Yauk, Marc A Beal

Toxicology· August 2025

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Applying New Approach Methods for Toxicokinetics for Chemical Risk Assessment.
John F Wambaugh, Katie Paul Friedman, Marc A Beal, Ivy Moffat, Michael F Hughes

Chem Res Toxicol· August 2025

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Benchmark Response (BMR) Values for In Vivo Mutagenicity Endpoints.
Paul A White, Guangchao Chen, Nikolai Chepelev, Madison A Bell, Lauren R Gallant, Marc A Beal

Environ Mol Mutagen· April 2025

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High-throughput transcriptomics toxicity assessment of eleven data-poor bisphenol A alternatives.
Marc A Beal, Melanie C Coughlan, Andrée Nunnikhoven, Matthew Gagné, Tara S Barton-Maclaren

Environ Pollut· November 2024

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Human next-generation risk assessment of trichothecene toxicity.
Marc A Beal, Denis Habauzit, Laure Khoury, Marc Audebert

Food Chem Toxicol· October 2024

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Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT).
Barbara L Parsons, Marc A Beal, Kerry L Dearfield, George R Douglas, Min Gi

Environ Mol Mutagen· June 2024

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The functional mutational landscape of the gene.
Marc A Beal, Matthew J Meier, Angela Dykes, Carole L Yauk, Iain B Lambert

iScience· December 2023

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Interpretation of in vitro concentration-response data for risk assessment and regulatory decision-making: Report from the 2022 IWGT quantitative analysis expert working group meeting.
Marc A Beal, Guangchao Chen, Kerry L Dearfield, Min Gi, Bhaskar Gollapudi

Environ Mol Mutagen· December 2023

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Editorial: toxicogenomics (TGx) in hazard and risk assessment.
Marc A Beal, Logan J Everett

Front Toxicol· September 2023

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Quantitative in vitro to in vivo extrapolation of genotoxicity data provides protective estimates of in vivo dose.
Marc A Beal, Marc Audebert, Tara Barton-Maclaren, Hannah Battaion, Jeffrey C Bemis

Environ Mol Mutagen· February 2023

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In vitro transcriptomic analyses reveal pathway perturbations, estrogenic activities, and potencies of data-poor BPA alternative chemicals.
Geronimo Matteo, Karen Leingartner, Andrea Rowan-Carroll, Matthew Meier, Andrew Williams, Marc A Beal

Toxicol Sci· February 2023

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Establishing a quantitative framework for regulatory interpretation of genetic toxicity dose-response data: Margin of exposure case study of 48 compounds with both in vivo mutagenicity and carcinogenicity dose-response data.
Nikolai Chepelev, Alexandra S Long, Marc Beal, Tara Barton-Maclaren, George Johnson

Environ Mol Mutagen· January 2023

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Comprehensive interpretation of in vitro micronucleus test results for 292 chemicals: from hazard identification to risk assessment application.
Byron Kuo, Marc A Beal, John W Wills, Paul A White, Francesco Marchetti

Arch Toxicol· July 2022

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Phthalates and alternative plasticizers differentially affect phenotypic parameters in gonadal somatic and germ cell lines†.
Abishankari Rajkumar, Trang Luu, Marc A Beal, Tara S Barton-Maclaren, Barbara F Hales

Biol Reprod· March 2022

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The Effects of Organophosphate Esters Used as Flame Retardants and Plasticizers on Granulosa, Leydig, and Spermatogonial Cells Analyzed Using High-Content Imaging.
Xiaotong Wang, Trang Luu, Marc A Beal, Tara S Barton-Maclaren, Bernard Robaire

Toxicol Sci· March 2022

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Implementing in vitro bioactivity data to modernize priority setting of chemical inventories.
Marc A Beal, Matthew Gagne, Sunil A Kulkarni, Grace Patlewicz, Russell S Thomas

ALTEX· January 2022

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Canadian Regulatory Perspective on Next Generation Risk Assessments for Pest Control Products and Industrial Chemicals.
Yadvinder Bhuller, Deborah Ramsingh, Marc Beal, Sunil Kulkarni, Matthew Gagne

Front Toxicol· November 2021

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Approaches In Carcinogenicity Hazard Assessment: Current Status and Future Needs.
Raymond R Tice, Arianna Bassan, Alexander Amberg, Lennart T Anger, Marc A Beal

Comput Toxicol· November 2021

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Elucidation of the Effects of Bisphenol A and Structural Analogs on Germ and Steroidogenic Cells Using Single Cell High-Content Imaging.
Abishankari Rajkumar, Trang Luu, Marc A Beal, Tara S Barton-Maclaren, Bernard Robaire

Toxicol Sci· April 2021

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Chemically induced mutations in a MutaMouse reporter gene inform mechanisms underlying human cancer mutational signatures.
Marc A Beal, Matthew J Meier, Danielle P LeBlanc, Clotilde Maurice, Jason M O'Brien

Commun Biol· August 2020

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Paternal exposure to benzo(a)pyrene induces genome-wide mutations in mouse offspring.
Marc A Beal, Matthew J Meier, Andrew Williams, Andrea Rowan-Carroll, Rémi Gagné

Commun Biol· April 2020

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Whole Genome Sequencing of the Mutamouse Model Reveals Strain- and Colony-Level Variation, and Genomic Features of the Transgene Integration Site.
Matthew J Meier, Marc A Beal, Andrew Schoenrock, Carole L Yauk, Francesco Marchetti

Sci Rep· September 2019

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In Utero Exposure to Benzo[a]pyrene Induces Ovarian Mutations at Doses That Deplete Ovarian Follicles in Mice.
Ulrike Luderer, Matthew J Meier, Gregory W Lawson, Marc A Beal, Carole L Yauk

Environ Mol Mutagen· June 2019

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From sperm to offspring: Assessing the heritable genetic consequences of paternal smoking and potential public health impacts.
Marc A Beal, Carole L Yauk, Francesco Marchetti

Mutat Res Rev Mutat Res· July 2017

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