Publications by authors named "Marc Huisman"

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Zr-mAb uptake interpretation requires the use of tissue to plasma ratios corrected for antibody catabolism.
Marc C Huisman, Johanna E E Pouw, Sandeep S V Golla, Damien Huglo, Franck Morschhauser

EJNMMI Res· September 2025

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A minimal physiologically-based pharmacokinetic modeling platform to predict intratumor exposure and receptor occupancy of an anti-LAG-3 monoclonal antibody.
Robin Michelet, Klas Petersson, Marc C Huisman, C Willemien Menke-van der Houven van Oordt, Iris H C Miedema

CPT Pharmacometrics Syst Pharmacol· March 2025

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Exploring the predictive potential of programmed death ligand 1 expression in healthy organs and lymph nodes as measured by F-BMS986-192 PET: pooled analysis of data from four solid tumor types.
Iris H C Miedema, Johanna E E Pouw, Anne Kwakman, Gerben J C Zwezerijnen, Marc C Huisman

J Immunother Cancer· June 2024

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The development process of 'fit-for-purpose' imaging biomarkers to characterize the tumor microenvironment.
Jakoba J Eertink, Idris Bahce, John C Waterton, Marc C Huisman, Ronald Boellaard

Front Med (Lausanne)· May 2024

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First exploration of the on-treatment changes in tumor and organ uptake of a radiolabeled anti PD-L1 antibody during chemoradiotherapy in patients with non-small cell lung cancer using whole body PET.
Johanna E E Pouw, Sayed M S Hashemi, Marc C Huisman, Jessica E Wijngaarden, Maarten Slebe

J Immunother Cancer· February 2024

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How to obtain the image-derived blood concentration from Zr-immuno-PET scans.
Jessica E Wijngaarden, Amina Ahbari, Johanna E E Pouw, Henri N J M Greuter, Idris Bahce, Marc C Huisman

EJNMMI Phys· February 2024

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Non-specific irreversible Zr-mAb uptake in tumours: evidence from biopsy-proven target-negative tumours using Zr-immuno-PET.
Jessica E Wijngaarden, Yvonne W S Jauw, Gerben J C Zwezerijnen, Berlinda J de Wit-van der Veen, Daniëlle J Vugts, Marc C Huisman

EJNMMI Res· February 2024

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Zr-Immuno-PET with Immune Checkpoint Inhibitors: Measuring Target Engagement in Healthy Organs.
Iris H C Miedema, Jessica E Wijngaarden, Johanna E E Pouw, Gerben J C Zwezerijnen, Hylke J Sebus, Marc C Huisman

Cancers (Basel)· November 2023

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Clinical validation of translational antibody PBPK model using tissue distribution data generated with Zr-immuno-PET imaging.
Shufang Liu, Zhe Li, Marc Huisman, Dhaval K Shah

J Pharmacokinet Pharmacodyn· October 2023

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Community Survey Results Show that Standardisation of Preclinical Imaging Techniques Remains a Challenge.
Adriana A S Tavares, Laura Mezzanotte, Wendy McDougald, Monique R Bernsen, Christian Vanhove, Marc C Huisman

Mol Imaging Biol· June 2023

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Validation of simplified uptake measures against dynamic Patlak K for quantification of lesional Zr-Immuno-PET antibody uptake.
Jessica E Wijngaarden, Marc C Huisman, Yvonne W S Jauw, Guus A M S van Dongen, Henri N J M Greuter

Eur J Nucl Med Mol Imaging· June 2023

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Zr-immuno-PET using the anti-LAG-3 tracer [Zr]Zr-BI 754111: demonstrating target specific binding in NSCLC and HNSCC.
Iris H C Miedema, Marc C Huisman, Gerben J C Zwezerijnen, Rolf Grempler, Alejandro Perez Pitarch

Eur J Nucl Med Mol Imaging· June 2023

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Characterizing the Bone Marrow Environment in Advanced-Stage Myelofibrosis during Ruxolitinib Treatment Using PET/CT and MRI: A Pilot Study.
Stefanie Slot, Cristina Lavini, Gerben J C Zwezerijnen, Bouke J H Boden, J Tim Marcus, Marc C Huisman

Tomography· February 2023

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Optimal imaging time points considering accuracy and precision of Patlak linearization for Zr-immuno-PET: a simulation study.
Jessica E Wijngaarden, Marc C Huisman, Johanna E E Pouw, C Willemien Menke-van der Houven van Oordt, Yvonne W S Jauw

EJNMMI Res· September 2022

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PD-L1 PET/CT Imaging with Radiolabeled Durvalumab in Patients with Advanced-Stage Non-Small Cell Lung Cancer.
Jasper Smit, Frank J Borm, Anna-Larissa N Niemeijer, Marc C Huisman, Otto S Hoekstra

J Nucl Med· May 2022

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Praluzatamab Ravtansine, a CD166-Targeting Antibody-Drug Conjugate, in Patients with Advanced Solid Tumors: An Open-Label Phase I/II Trial.
Valentina Boni, Mary J Fidler, Hendrik-Tobias Arkenau, Alexander Spira, Funda Meric-Bernstam, Marc C Huisman

Clin Cancer Res· May 2022

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PET-CT Imaging of Polymeric Nanoparticle Tumor Accumulation in Patients.
Iris H C Miedema, Gerben J C Zwezerijnen, Marc C Huisman, Ellen Doeleman, Ron H J Mathijssen

Adv Mater· May 2022

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Study of Zr-Pembrolizumab PET/CT in Patients With Advanced-Stage Non-Small Cell Lung Cancer.
Anna-Larissa N Niemeijer, Daniela E Oprea-Lager, Marc C Huisman, Otto S Hoekstra, Ronald Boellaard

J Nucl Med· March 2022

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Noise sensitivity of Zr-Immuno-PET radiomics based on count-reduced clinical images.
Ananthi Somasundaram, David Vállez García, Elisabeth Pfaehler, Yvonne W S Jauw, Josée M Zijlstra, Marc C Huisman

EJNMMI Phys· March 2022

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3D Convolutional Neural Network-Based Denoising of Low-Count Whole-Body F-Fluorodeoxyglucose and Zr-Rituximab PET Scans.
Bart M de Vries, Sandeep S V Golla, Gerben J C Zwezerijnen, Otto S Hoekstra, Yvonne W S Jauw, Marc C Huisman

Diagnostics (Basel)· February 2022

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Potential and pitfalls of Zr-immuno-PET to assess target status: Zr-trastuzumab as an example.
Marc C Huisman, C Willemien Menke-van der Houven van Oordt, Josée M Zijlstra, Otto S Hoekstra, Ronald Boellaard

EJNMMI Res· August 2021

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Performance of nanoScan PET/CT and PET/MR for quantitative imaging of F and Zr as compared with ex vivo biodistribution in tumor-bearing mice.
Marion Chomet, Maxime Schreurs, Ricardo Vos, Mariska Verlaan, Esther J Kooijman, Marc C Huisman

EJNMMI Res· June 2021

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Application of [18F]FLT-PET in pulmonary arterial hypertension: a clinical study in pulmonary arterial hypertension patients and unaffected bone morphogenetic protein receptor type 2 mutation carriers.
Liza Botros, Samara M A Jansen, Ali Ashek, Onno A Spruijt, Jelco Tramper, Marc C Huisman

Pulm Circ· June 2021

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The Role of Zr-Immuno-PET in Navigating and Derisking the Development of Biopharmaceuticals.
Guus A M S van Dongen, Wissam Beaino, Albert D Windhorst, Gerben J C Zwezerijnen, Daniela E Oprea-Lager, Marc C Huisman

J Nucl Med· April 2021

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Value of CMR and PET in Predicting Ventricular Arrhythmias in Ischemic Cardiomyopathy Patients Eligible for ICD.
Mischa T Rijnierse, Anne-Lotte C J van der Lingen, Stefan de Haan, Marthe A J Becker, Hendrik J Harms, Marc C Huisman

JACC Cardiovasc Imaging· August 2020

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