Publications by authors named "Marc Lemonnier"

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Meropenem-ANT3310, a unique β-lactam-β-lactamase inhibitor combination with expanded antibacterial spectrum against Gram-negative pathogens including carbapenem-resistant .
Magdalena Zalacain, Pauline Achard, Agustina Llanos, Ian Morrissey, Stephen Hawser, Marc Lemonnier

Antimicrob Agents Chemother· March 2024

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Higher levels of Pseudomonas aeruginosa LasB elastase expression are associated with early-stage infection in cystic fibrosis patients.
Agustina Llanos, Pauline Achard, Justine Bousquet, Clarisse Lozano, Magdalena Zalacain, Marc Lemonnier

Sci Rep· August 2023

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Chemical Optimization of Selective LasB Elastase Inhibitors and Their Impact on LasB-Mediated Activation of IL-1β in Cellular and Animal Infection Models.
Martin J Everett, David T Davies, Simon Leiris, Nicolas Sprynski, Agustina Llanos, Marc Lemonnier

ACS Infect Dis· February 2023

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Novel Specific Metallo-β-Lactamase Inhibitor ANT2681 Restores Meropenem Activity to Clinically Effective Levels against NDM-Positive .
Magdalena Zalacain, Clarisse Lozano, Agustina Llanos, Nicolas Sprynski, Thomas Valmont, Marc Lemonnier

Antimicrob Agents Chemother· May 2021

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Virtual Screening Approach to Identifying a Novel and Tractable Series of Elastase Inhibitors.
Simon Leiris, David T Davies, Nicolas Sprynski, Jérôme Castandet, Lilha Beyria, Marc Lemonnier

ACS Med Chem Lett· February 2021

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Discovery of , a Novel Broad-Spectrum Serine β-Lactamase Inhibitor of the Diazabicyclooctane Class, Which Strongly Potentiates Meropenem Activity against Carbapenem-Resistant Enterobacterales and .
David T Davies, Simon Leiris, Magdalena Zalacain, Nicolas Sprynski, Jérôme Castandet, Marc Lemonnier

J Med Chem· December 2020

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ANT2681: SAR Studies Leading to the Identification of a Metallo-β-lactamase Inhibitor with Potential for Clinical Use in Combination with Meropenem for the Treatment of Infections Caused by NDM-Producing .
David T Davies, Simon Leiris, Nicolas Sprynski, Jérôme Castandet, Clarisse Lozano, Marc Lemonnier

ACS Infect Dis· September 2020

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SAR Studies Leading to the Identification of a Novel Series of Metallo-β-lactamase Inhibitors for the Treatment of Carbapenem-Resistant Enterobacteriaceae Infections That Display Efficacy in an Animal Infection Model.
Simon Leiris, Alicia Coelho, Jérôme Castandet, Maëlle Bayet, Clarisse Lozano, Marc Lemonnier

ACS Infect Dis· January 2019

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Discovery of a Novel Metallo-β-Lactamase Inhibitor That Potentiates Meropenem Activity against Carbapenem-Resistant Enterobacteriaceae.
Martin Everett, Nicolas Sprynski, Alicia Coelho, Jérôme Castandet, Maëlle Bayet, Marc Lemonnier

Antimicrob Agents Chemother· May 2018

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A common origin for the bacterial toxin-antitoxin systems parD and ccd, suggested by analyses of toxin/target and toxin/antitoxin interactions.
Andrew B Smith, Juan López-Villarejo, Elizabeth Diago-Navarro, Lesley A Mitchenall, Arjan Barendregt, Marc Lemonnier

PLoS One· February 2013

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Escherichia coli producing CNF1 toxin hijacks Tollip to trigger Rac1-dependent cell invasion.
Orane Visvikis, Laurent Boyer, Stéphanie Torrino, Anne Doye, Marc Lemonnier

Traffic· May 2011

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parD toxin-antitoxin system of plasmid R1--basic contributions, biotechnological applications and relationships with closely-related toxin-antitoxin systems.
Elizabeth Diago-Navarro, Ana M Hernandez-Arriaga, Juan López-Villarejo, Ana J Muñoz-Gómez, Monique B Kamphuis, Marc Lemonnier

FEBS J· August 2010

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Generational coexistence and ancestor's inhibition in bacterial populations.
Fernando Baquero, Marc Lemonnier

FEMS Microbiol Rev· September 2009

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Novel Escherichia coli RF1 mutants with decreased translation termination activity and increased sensitivity to the cytotoxic effect of the bacterial toxins Kid and RelE.
Elizabeth Diago-Navarro, Liliana Mora, Richard H Buckingham, Ramón Díaz-Orejas, Marc Lemonnier

Mol Microbiol· January 2009

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The evolution of contact-dependent inhibition in non-growing populations of Escherichia coli.
Marc Lemonnier, Bruce R Levin, Tony Romeo, Kim Garner, María-Rosario Baquero

Proc Biol Sci· January 2008

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Rho GTPase-activating bacterial toxins: from bacterial virulence regulation to eukaryotic cell biology.
Marc Lemonnier, Luce Landraud, Emmanuel Lemichez

FEMS Microbiol Rev· September 2007

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Interactions between the toxin Kid of the bacterial parD system and the antitoxins Kis and MazE.
Monique B Kamphuis, Maria Chiara Monti, Robert H H van den Heuvel, Sandra Santos-Sierra, Gert E Folkers, Marc Lemonnier

Proteins· April 2007

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Model for RNA binding and the catalytic site of the RNase Kid of the bacterial parD toxin-antitoxin system.
Monique B Kamphuis, Alexandre M J J Bonvin, Maria Chiara Monti, Marc Lemonnier, Ana Muñoz-Gómez

J Mol Biol· March 2006

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RNase/anti-RNase activities of the bacterial parD toxin-antitoxin system.
Ana J Muñoz-Gómez, Marc Lemonnier, Sandra Santos-Sierra, Alfredo Berzal-Herranz, Ramón Díaz-Orejas

J Bacteriol· May 2005

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Insights into the specificity of RNA cleavage by the Escherichia coli MazF toxin.
Ana J Muñoz-Gómez, Sandra Santos-Sierra, Alfredo Berzal-Herranz, Marc Lemonnier, Ramón Díaz-Orejas

FEBS Lett· June 2004

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Identification of residues of the kid toxin involved in autoregulation of the parD system.
Marc Lemonnier, Sandra Santos-Sierra, Consolación Pardo-Abarrio, Ramón Díaz-Orejas

J Bacteriol· January 2004

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Non-cytotoxic variants of the Kid protein that retain their auto-regulatory activity.
Sandra Santos-Sierra, Marc Lemonnier, Belen Nuñez, David Hargreaves, John Rafferty

Plasmid· September 2003

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Bacteriophage P1 Ban protein is a hexameric DNA helicase that interacts with and substitutes for Escherichia coli DnaB.
Marc Lemonnier, Günter Ziegelin, Tobias Reick, Ana Muñoz Gómez, Ramón Díaz-Orejas

Nucleic Acids Res· July 2003

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Differential effects of Kid toxin on two modes of replication of lambdoid plasmids suggest that this toxin acts before, but not after, the assembly of the replication complex.
Katarzyna Potrykus, Sandra Santos, Marc Lemonnier, Ramon Diaz-Orejas, Grzegorz Węgrzyn

Microbiology (Reading)· August 2002

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Expression of the second lysine decarboxylase gene of Escherichia coli.
Marc Lemonnier, David Lane

Microbiology (Reading)· March 1998

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