Publications by authors named "Marc Pascal"

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Differential Virtual Screening (DVS) with Active and Inactive Molecular Models for Finding and Profiling GPCR Modulators: Case of the CCK1 Receptor.
Constantino Diaz, Pascal Leplatois, Patricia Angelloz-Nicoud, Marinette Lecomte, Annick Josse, Marc Pascal

Mol Inform· April 2011

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Proinflammatory role of vasopressin through V1b receptors in hapten-induced experimental colitis in rodents: implication in IBD.
Laurent Ferrier, Claudine Serradeil-Le Gal, Anke M Schulte, Valentina Vasina, Eric Gaultier, Marc Pascal

Am J Physiol Gastrointest Liver Physiol· December 2010

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Biological characterization of rodent and human vasopressin V1b receptors using SSR-149415, a nonpeptide V1b receptor ligand.
Claudine Serradeil-Le Gal, Danièle Raufaste, Sylvain Derick, Jörg Blankenstein, John Allen, Marc Pascal

Am J Physiol Regul Integr Comp Physiol· August 2007

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In vitro and in vivo pharmacological characterization of ethyl-4-[trans-4-[((2S)-2-hydroxy-3-[4-hydroxy-3[(methylsulfonyl)amino]-phenoxy]propyl) amino]cyclohexyl]benzoate hydrochloride (SAR150640), a new potent and selective human beta3-adrenoceptor agonist for the treatment of preterm labor.
Tiziano Croci, Roberto Cecchi, Pietro Marini, Céline Rouget, Nunzia Viviani, Marc Pascal

J Pharmacol Exp Ther· June 2007

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SSR126768A (4-chloro-3-[(3R)-(+)-5-chloro-1-(2,4-dimethoxybenzyl)-3-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl]-N-ethyl-N-(3-pyridylmethyl)-benzamide, hydrochloride): a new selective and orally active oxytocin receptor antagonist for the prevention of preterm labor.
Claudine Serradeil-Le Gal, Gérard Valette, Loïc Foulon, Guy Germain, Charles Advenier, Marc Pascal

J Pharmacol Exp Ther· April 2004

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Pancreatic vasopressin V1b receptors: characterization in In-R1-G9 cells and localization in human pancreas.
Viviane Folny, Danielle Raufaste, Ludovit Lukovic, Brigitte Pouzet, Pierrick Rochard, Marc Pascal

Am J Physiol Endocrinol Metab· September 2003

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SSR240600 [(R)-2-(1-[2-[4-[2-[3,5-bis(trifluoromethyl)phenyl]acetyl]-2-(3,4-dichlorophenyl)-2-morpholinyl]ethyl]- 4-piperidinyl)-2-methylpropanamide], a centrally active nonpeptide antagonist of the tachykinin neurokinin-1 receptor: I. biochemical and pharmacological characterization.
Xavier Emonds-Alt, Vincenzo Proietto, Régis Steinberg, Florence Oury-Donat, Xavier Vigé, Marc Pascal

J Pharmacol Exp Ther· December 2002

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Structure and stereochemistry of the active metabolite of clopidogrel.
Jean-Marie Pereillo, Mohamed Maftouh, Alain Andrieu, Marie-Francoise Uzabiaga, Olivier Fedeli, Marc Pascal

Drug Metab Dispos· November 2002

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Biochemical and pharmacological activities of SSR 146977, a new potent nonpeptide tachykinin NK3 receptor antagonist.
Xavier Emonds-Alt, Vincenzo Proietto, Régis Steinberg, Charles Advenier, Samira Daoui, Marc Pascal

Can J Physiol Pharmacol· May 2002

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4-(2-Chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]5-methyl-N-(2-propynyl)-1,3-thiazol-2-amine hydrochloride (SSR125543A): a potent and selective corticotrophin-releasing factor(1) receptor antagonist. I. Biochemical and pharmacological characterization.
Danielle Gully, Michel Geslin, Laurence Serva, Evelyne Fontaine, Pierre Roger, Marc Pascal

J Pharmacol Exp Ther· April 2002

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Anxiolytic- and antidepressant-like effects of the non-peptide vasopressin V1b receptor antagonist, SSR149415, suggest an innovative approach for the treatment of stress-related disorders.
Guy Griebel, Jacques Simiand, Claudine Serradeil-Le Gal, Jean Wagnon, Marc Pascal

Proc Natl Acad Sci U S A· April 2002

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Characterization of (2S,4R)-1-[5-chloro-1-[(2,4-dimethoxyphenyl)sulfonyl]-3-(2-methoxy-phenyl)-2-oxo-2,3-dihydro-1H-indol-3-yl]-4-hydroxy-N,N-dimethyl-2-pyrrolidine carboxamide (SSR149415), a selective and orally active vasopressin V1b receptor antagonist.
Claudine Serradeil-Le Gal, Jean Wagnon, Jacques Simiand, Guy Griebel, Colette Lacour, Marc Pascal

J Pharmacol Exp Ther· March 2002

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